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Items: 1 to 20 of 58

1.

Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.

He P, Lee SJ, Lin S, Seidler U, Lang F, Fejes-Toth G, Naray-Fejes-Toth A, Yun CC.

Mol Biol Cell. 2011 Oct;22(20):3812-25. doi: 10.1091/mbc.E11-04-0328. Epub 2011 Aug 24.

2.

Second AKT: the rise of SGK in cancer signalling.

Bruhn MA, Pearson RB, Hannan RD, Sheppard KE.

Growth Factors. 2010 Dec;28(6):394-408. doi: 10.3109/08977194.2010.518616. Epub 2010 Oct 5. Review.

PMID:
20919962
3.

Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.

Wiemuth D, Lott JS, Ly K, Ke Y, Teesdale-Spittle P, Snyder PM, McDonald FJ.

PLoS One. 2010 Aug 13;5(8):e12163. doi: 10.1371/journal.pone.0012163.

4.

Significance of SGK1 in the regulation of neuronal function.

Lang F, Strutz-Seebohm N, Seebohm G, Lang UE.

J Physiol. 2010 Sep 15;588(Pt 18):3349-54. doi: 10.1113/jphysiol.2010.190926. Epub 2010 Jun 7. Review.

5.

The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.

Böhmer C, Sopjani M, Klaus F, Lindner R, Laufer J, Jeyaraj S, Lang F, Palmada M.

Cell Physiol Biochem. 2010;25(6):723-32. doi: 10.1159/000315092. Epub 2010 May 18.

6.

mTOR complex-2 activates ENaC by phosphorylating SGK1.

Lu M, Wang J, Jones KT, Ives HE, Feldman ME, Yao LJ, Shokat KM, Ashrafi K, Pearce D.

J Am Soc Nephrol. 2010 May;21(5):811-8. doi: 10.1681/ASN.2009111168. Epub 2010 Mar 25.

7.

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M.

Sci Signal. 2010 Jan 12;3(104):ra3. doi: 10.1126/scisignal.2000475.

8.

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

Amato R, D'Antona L, Porciatti G, Agosti V, Menniti M, Rinaldo C, Costa N, Bellacchio E, Mattarocci S, Fuiano G, Soddu S, Paggi MG, Lang F, Perrotti N.

J Mol Med (Berl). 2009 Dec;87(12):1221-39. doi: 10.1007/s00109-009-0525-5. Epub 2009 Sep 11.

PMID:
19756449
9.

Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.

Won M, Park KA, Byun HS, Kim YR, Choi BL, Hong JH, Park J, Seok JH, Lee YH, Cho CH, Song IS, Kim YK, Shen HM, Hur GM.

J Hepatol. 2009 Jul;51(1):67-76. doi: 10.1016/j.jhep.2009.02.027. Epub 2009 Apr 16.

PMID:
19447520
10.

Large-scale proteomics analysis of the human kinome.

Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H.

Mol Cell Proteomics. 2009 Jul;8(7):1751-64. doi: 10.1074/mcp.M800588-MCP200. Epub 2009 Apr 15.

11.

Regulation of a third conserved phosphorylation site in SGK1.

Chen W, Chen Y, Xu BE, Juang YC, Stippec S, Zhao Y, Cobb MH.

J Biol Chem. 2009 Feb 6;284(6):3453-60. doi: 10.1074/jbc.M807502200. Epub 2008 Dec 9.

12.

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).

García-Martínez JM, Alessi DR.

Biochem J. 2008 Dec 15;416(3):375-85. doi: 10.1042/BJ20081668.

PMID:
18925875
13.

An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.

Raikwar NS, Snyder PM, Thomas CP.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1440-8. doi: 10.1152/ajprenal.90239.2008. Epub 2008 Aug 27.

14.

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M.

Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007.

15.

A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.

Arteaga MF, Coric T, Straub C, Canessa CM.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4459-64. doi: 10.1073/pnas.0800958105. Epub 2008 Mar 11.

16.

Regulation Fe65 localization to the nucleus by SGK1 phosphorylation of its Ser566 residue.

Lee EJ, Chun J, Hyun S, Ahn HR, Jeong JM, Hong SK, Hong JT, Chang IK, Jeon HY, Han YS, Auh CK, Park JI, Kang SS.

BMB Rep. 2008 Jan 31;41(1):41-7.

17.

Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3.

Böhmer C, Palmada M, Kenngott C, Lindner R, Klaus F, Laufer J, Lang F.

FEBS Lett. 2007 Dec 11;581(29):5586-90. Epub 2007 Nov 20.

18.

Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP.

Zhao B, Lehr R, Smallwood AM, Ho TF, Maley K, Randall T, Head MS, Koretke KK, Schnackenberg CG.

Protein Sci. 2007 Dec;16(12):2761-9. Epub 2007 Oct 26.

19.

Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4.

Jeyaraj S, Boehmer C, Lang F, Palmada M.

Biochem Biophys Res Commun. 2007 May 11;356(3):629-35. Epub 2007 Mar 12.

PMID:
17382906
20.

Patterns of somatic mutation in human cancer genomes.

Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR.

Nature. 2007 Mar 8;446(7132):153-8.

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