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Items: 9


Reconstitution of the augmin complex provides insights into its architecture and function.

Hsia KC, Wilson-Kubalek EM, Dottore A, Hao Q, Tsai KL, Forth S, Shimamoto Y, Milligan RA, Kapoor TM.

Nat Cell Biol. 2014 Sep;16(9):852-63. doi: 10.1038/ncb3030. Epub 2014 Aug 31.


Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.

Tsai CY, Ngo B, Tapadia A, Hsu PH, Wu G, Lee WH.

J Biol Chem. 2011 Aug 26;286(34):30097-106. doi: 10.1074/jbc.M111.266767. Epub 2011 Jun 24.


Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS.

EMBO J. 2011 Apr 20;30(8):1520-35. doi: 10.1038/emboj.2011.63. Epub 2011 Mar 11.


Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.

Wu G, Wei R, Cheng E, Ngo B, Lee WH.

Mol Biol Cell. 2009 Nov;20(22):4686-95. doi: 10.1091/mbc.E08-11-1123. Epub 2009 Sep 23.


HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.

Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L.

Curr Biol. 2009 May 26;19(10):816-26. doi: 10.1016/j.cub.2009.04.033. Epub 2009 May 7.


The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Uehara R, Nozawa RS, Tomioka A, Petry S, Vale RD, Obuse C, Goshima G.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6998-7003. doi: 10.1073/pnas.0901587106. Epub 2009 Apr 14.


Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle.

Goshima G, Mayer M, Zhang N, Stuurman N, Vale RD.

J Cell Biol. 2008 May 5;181(3):421-9. doi: 10.1083/jcb.200711053. Epub 2008 Apr 28.


Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells.

Wu G, Lin YT, Wei R, Chen Y, Shan Z, Lee WH.

Mol Cell Biol. 2008 Jun;28(11):3652-62. doi: 10.1128/MCB.01923-07. Epub 2008 Mar 24.


Immunomic analysis of human sarcoma.

Lee SY, Obata Y, Yoshida M, Stockert E, Williamson B, Jungbluth AA, Chen YT, Old LJ, Scanlan MJ.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2651-6. Epub 2003 Feb 24.

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