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Items: 14

1.

Yangonin blocks tumor necrosis factor-α-induced nuclear factor-κB-dependent transcription by inhibiting the transactivation potential of the RelA/p65 subunit.

Ma J, Liang H, Jin HR, Dat NT, Zhang SY, Jiang YZ, Nan JX, Li D, Wu X, Lee JJ, Jin X.

J Pharmacol Sci. 2012;118(4):447-54.

2.

Kavalactones Yangonin and Methysticin induce apoptosis in human hepatocytes (HepG2) in vitro.

Tang J, Dunlop RA, Rowe A, Rodgers KJ, Ramzan I.

Phytother Res. 2011 Mar;25(3):417-23. doi: 10.1002/ptr.3283.

PMID:
20734326
3.

Final report on the safety assessment of Piper methysticum leaf/root/stem extract and Piper methysticum root extract.

Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW; Cosmetic Ingredient Review Expert Panel., Andersen FA.

Int J Toxicol. 2009 Nov-Dec;28(6 Suppl):175S-88S. doi: 10.1177/1091581809350934.

PMID:
19966149
4.

Permeability studies of Kavalactones using a Caco-2 cell monolayer model.

Matthias A, Blanchfield JT, Penman KG, Bone KM, Toth I, Lehmann RP.

J Clin Pharm Ther. 2007 Jun;32(3):233-9.

PMID:
17489874
5.

Kavalactones fail to inhibit alcohol dehydrogenase in vitro.

Anke J, Fu S, Ramzan I.

Phytomedicine. 2006 Feb;13(3):192-5.

PMID:
16428028
6.

Superheated water chromatography-nuclear magnetic resonance spectroscopy of kava lactones.

Chienthavorn O, Smith RM, Wilson ID, Wright B, Lenz EM.

Phytochem Anal. 2005 May-Jun;16(3):217-21.

PMID:
15997856
8.
9.

Kava does not display metabolic toxicity in a homogeneous cellular assay.

Zou L, Harkey MR, Henderson GL, Dike LE.

Planta Med. 2004 Apr;70(4):289-92.

PMID:
15095141
10.

In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones.

Nerurkar PV, Dragull K, Tang CS.

Toxicol Sci. 2004 May;79(1):106-11.

PMID:
14737001
11.

Isolation and synthesis of TNF-alpha release inhibitors from Fijian kawa (Piper methysticum).

Hashimoto T, Suganuma M, Fujiki H, Yamada M, Kohno T, Asakawa Y.

Phytomedicine. 2003 May;10(4):309-17.

PMID:
12809361
12.

Effects of intrinsic fluorescence and quenching on fluorescence-based screening of natural products.

Zou L, Harkey MR, Henderson GL.

Phytomedicine. 2002 Apr;9(3):263-7.

PMID:
12046870
13.

Interaction of various Piper methysticum cultivars with CNS receptors in vitro.

Dinh LD, Simmen U, Bueter KB, Bueter B, Lundstrom K, Schaffner W.

Planta Med. 2001 Jun;67(4):306-11.

PMID:
11458444
14.
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