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Items: 1 to 20 of 7116


Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.

Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J.

Nat Cell Biol. 2017 Sep;19(9):1027-1036. doi: 10.1038/ncb3593. Epub 2017 Aug 14.


Comparative analysis of LytS/LytTR-type histidine kinase/response regulator systems in γ-proteobacteria.

Behr S, Brameyer S, Witting M, Schmitt-Kopplin P, Jung K.

PLoS One. 2017 Aug 10;12(8):e0182993. doi: 10.1371/journal.pone.0182993. eCollection 2017.


Metabolic engineering of CHO cells for the development of a robust protein production platform.

Gupta SK, Srivastava SK, Sharma A, Nalage VHH, Salvi D, Kushwaha H, Chitnis NB, Shukla P.

PLoS One. 2017 Aug 1;12(8):e0181455. doi: 10.1371/journal.pone.0181455. eCollection 2017.


Metabolic control of the scaffold protein TKS5 in tissue-invasive, proinflammatory T cells.

Shen Y, Wen Z, Li Y, Matteson EL, Hong J, Goronzy JJ, Weyand CM.

Nat Immunol. 2017 Sep;18(9):1025-1034. doi: 10.1038/ni.3808. Epub 2017 Jul 24.


13 C metabolic flux profiling of Pichia pastoris grown in aerobic batch cultures on glucose revealed high relative anabolic use of TCA cycle and limited incorporation of provided precursors of branched-chain amino acids.

Zhang M, Yu XW, Xu Y, Jouhten P, Swapna GVT, Glaser RW, Hunt JF, Montelione GT, Maaheimo H, Szyperski T.

FEBS J. 2017 Sep;284(18):3100-3113. doi: 10.1111/febs.14180. Epub 2017 Aug 7.


8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle.

Vartanian V, Tumova J, Dobrzyn P, Dobrzyn A, Nakabeppu Y, Lloyd RS, Sampath H.

PLoS One. 2017 Jul 20;12(7):e0181687. doi: 10.1371/journal.pone.0181687. eCollection 2017.


Chrysogine Biosynthesis Is Mediated by a Two-Module Nonribosomal Peptide Synthetase.

Wollenberg RD, Saei W, Westphal KR, Klitgaard CS, Nielsen KL, Lysøe E, Gardiner DM, Wimmer R, Sondergaard TE, Sørensen JL.

J Nat Prod. 2017 Jul 28;80(7):2131-2135. doi: 10.1021/acs.jnatprod.6b00822. Epub 2017 Jul 14.


Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes.

Gibb AA, Lorkiewicz PK, Zheng YT, Zhang X, Bhatnagar A, Jones SP, Hill BG.

Biochem J. 2017 Aug 7;474(16):2785-2801. doi: 10.1042/BCJ20170474.


The comprehensive liver transcriptome of two cattle breeds with different intramuscular fat content.

Wang X, Zhang Y, Zhang X, Wang D, Jin G, Li B, Xu F, Cheng J, Zhang F, Wu S, Rui S, He J, Zhang R, Liu W.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):1018-1025. doi: 10.1016/j.bbrc.2017.06.157. Epub 2017 Jun 29.


Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria.

Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT.

J Biol Chem. 2017 Aug 25;292(34):14176-14187. doi: 10.1074/jbc.M117.786582. Epub 2017 Jun 29.


One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas.

Campilongo R, Fung RKY, Little RH, Grenga L, Trampari E, Pepe S, Chandra G, Stevenson CEM, Roncarati D, Malone JG.

PLoS Genet. 2017 Jun 28;13(6):e1006839. doi: 10.1371/journal.pgen.1006839. eCollection 2017 Jun.


Biological, biochemical and histological features of Bradybaena similaris (Gastropoda: Pulmonata) infected by Heterorabditis indica (Rhabditida: Heterorhabditidae) strain LPP1.

Tunholi VM, Tunholi-Alves VM, Monteiro CO, Silva LCD, Dolinski CM, Castro RN, Bittencourt VREP, Silva JPD, Freire Martins IV.

Exp Parasitol. 2017 Aug;179:28-35. doi: 10.1016/j.exppara.2017.06.004. Epub 2017 Jun 24.


Should Hyperoxia Be Avoided During Sepsis? An Experimental Study in Ovine Peritonitis.

He X, Su F, Xie K, Taccone FS, Donadello K, Vincent JL.

Crit Care Med. 2017 Oct;45(10):e1060-e1067. doi: 10.1097/CCM.0000000000002524.


Kinetic and Thermodynamic Analysis of Acetyl-CoA Activation of Staphylococcus aureus Pyruvate Carboxylase.

Westerhold LE, Bridges LC, Shaikh SR, Zeczycki TN.

Biochemistry. 2017 Jul 11;56(27):3492-3506. doi: 10.1021/acs.biochem.7b00383. Epub 2017 Jun 28.


Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.

Watanabe R, Shirai T, Namkoong H, Zhang H, Berry GJ, Wallis BB, Schaefgen B, Harrison DG, Tremmel JA, Giacomini JC, Goronzy JJ, Weyand CM.

J Clin Invest. 2017 Jun 30;127(7):2725-2738. doi: 10.1172/JCI92167. Epub 2017 Jun 12.


Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice.

Patel DP, Krausz KW, Xie C, Beyoğlu D, Gonzalez FJ, Idle JR.

PLoS One. 2017 May 16;12(5):e0177953. doi: 10.1371/journal.pone.0177953. eCollection 2017.


Properties of Intermediates in the Catalytic Cycle of Oxalate Oxidoreductase and Its Suicide Inactivation by Pyruvate.

Pierce E, Mansoorabadi SO, Can M, Reed GH, Ragsdale SW.

Biochemistry. 2017 Jun 6;56(22):2824-2835. doi: 10.1021/acs.biochem.7b00222. Epub 2017 May 23.


Production of d-lactate using a pyruvate-producing Escherichia coli strain.

Akita H, Nakashima N, Hoshino T.

Biosci Biotechnol Biochem. 2017 Jul;81(7):1452-1455. doi: 10.1080/09168451.2017.1318697. Epub 2017 May 2.


Suppression of the Escherichia coli dnaA46 mutation by changes in the activities of the pyruvate-acetate node links DNA replication regulation to central carbon metabolism.

Tymecka-Mulik J, Boss L, Maciąg-Dorszyńska M, Matias Rodrigues JF, Gaffke L, Wosinski A, Cech GM, Szalewska-Pałasz A, Węgrzyn G, Glinkowska M.

PLoS One. 2017 Apr 27;12(4):e0176050. doi: 10.1371/journal.pone.0176050. eCollection 2017.


A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design.

Ragavan M, Kirpich A, Fu X, Burgess SC, McIntyre LM, Merritt ME.

Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1215-H1223. doi: 10.1152/ajpheart.00016.2017. Epub 2017 Apr 14.


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