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Items: 1 to 20 of 29

1.

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

Jonsson A, Isomaa B, Tuomi T, Taneera J, Salehi A, Nilsson P, Groop L, Lyssenko V.

Diabetes. 2009 Oct;58(10):2409-13. doi: 10.2337/db09-0246. Epub 2009 Jul 7.

2.

Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?

Towart R, Linders JT, Hermans AN, Rohrbacher J, van der Linde HJ, Ercken M, Cik M, Roevens P, Teisman A, Gallacher DJ.

J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):1-10. doi: 10.1016/j.vascn.2009.04.197. Epub 2009 May 9. Review.

PMID:
19439185
3.

In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.

Namkung W, Song Y, Mills AD, Padmawar P, Finkbeiner WE, Verkman AS.

J Biol Chem. 2009 Jun 5;284(23):15916-26. doi: 10.1074/jbc.M808021200. Epub 2009 Apr 13.

4.

Supramolecular assemblies and localized regulation of voltage-gated ion channels.

Dai S, Hall DD, Hell JW.

Physiol Rev. 2009 Apr;89(2):411-52. doi: 10.1152/physrev.00029.2007. Review.

5.

Neural KCNQ (Kv7) channels.

Brown DA, Passmore GM.

Br J Pharmacol. 2009 Apr;156(8):1185-95. doi: 10.1111/j.1476-5381.2009.00111.x. Epub 2009 Mar 9. Review.

6.

Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2.

Delpire E, Days E, Lewis LM, Mi D, Kim K, Lindsley CW, Weaver CD.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5383-8. doi: 10.1073/pnas.0812756106. Epub 2009 Mar 11.

7.

Chemical tools for K(+) channel biology.

Ahern CA, Kobertz WR.

Biochemistry. 2009 Jan 27;48(3):517-26. doi: 10.1021/bi8018515. Review.

8.

Structure, function, and modification of the voltage sensor in voltage-gated ion channels.

Börjesson SI, Elinder F.

Cell Biochem Biophys. 2008;52(3):149-74. doi: 10.1007/s12013-008-9032-5. Epub 2008 Nov 7. Review.

PMID:
18989792
9.

The domain and conformational organization in potassium voltage-gated ion channels.

Pischalnikova AV, Sokolova OS.

J Neuroimmune Pharmacol. 2009 Mar;4(1):71-82. doi: 10.1007/s11481-008-9130-6. Epub 2008 Oct 3. Review.

PMID:
18836841
10.

Cardiovascular KCNQ (Kv7) potassium channels: physiological regulators and new targets for therapeutic intervention.

Mackie AR, Byron KL.

Mol Pharmacol. 2008 Nov;74(5):1171-9. doi: 10.1124/mol.108.049825. Epub 2008 Aug 6. Review.

11.

KCNQ-encoded channels regulate Na+ transport across H441 lung epithelial cells.

Greenwood IA, Yeung SY, Hettiarachi S, Andersson M, Baines DL.

Pflugers Arch. 2009 Feb;457(4):785-94. doi: 10.1007/s00424-008-0557-7. Epub 2008 Jul 29.

PMID:
18663467
12.

K+ channel modulators for the treatment of neurological disorders and autoimmune diseases.

Wulff H, Zhorov BS.

Chem Rev. 2008 May;108(5):1744-73. doi: 10.1021/cr078234p. Review. No abstract available.

13.

Multiple KCNQ potassium channel subtypes mediate basal anion secretion from the human airway epithelial cell line Calu-3.

Moser SL, Harron SA, Crack J, Fawcett JP, Cowley EA.

J Membr Biol. 2008 Feb;221(3):153-63. doi: 10.1007/s00232-008-9093-9. Epub 2008 Feb 9.

PMID:
18264812
14.

Nervous system KV7 disorders: breakdown of a subthreshold brake.

Maljevic S, Wuttke TV, Lerche H.

J Physiol. 2008 Apr 1;586(7):1791-801. doi: 10.1113/jphysiol.2008.150656. Epub 2008 Jan 31. Review.

15.

Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.

Hernandez CC, Zaika O, Tolstykh GP, Shapiro MS.

J Physiol. 2008 Apr 1;586(7):1811-21. doi: 10.1113/jphysiol.2007.148304. Epub 2008 Jan 31. Review.

16.

Kv7.1 (KCNQ1) properties and channelopathies.

Peroz D, Rodriguez N, Choveau F, Baró I, Mérot J, Loussouarn G.

J Physiol. 2008 Apr 1;586(7):1785-9. doi: 10.1113/jphysiol.2007.148254. Epub 2008 Jan 3. Review.

17.

A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.

Niswender CM, Johnson KA, Luo Q, Ayala JE, Kim C, Conn PJ, Weaver CD.

Mol Pharmacol. 2008 Apr;73(4):1213-24. doi: 10.1124/mol.107.041053. Epub 2008 Jan 2.

18.

Physiologic principles underlying ion channelopathies.

Cannon SC.

Neurotherapeutics. 2007 Apr;4(2):174-83. Review.

PMID:
17395127
19.

Role of cholinergic-activated KCa1.1 (BK), KCa3.1 (SK4) and KV7.1 (KCNQ1) channels in mouse colonic Cl- secretion.

Matos JE, Sausbier M, Beranek G, Sausbier U, Ruth P, Leipziger J.

Acta Physiol (Oxf). 2007 Mar;189(3):251-8.

PMID:
17305705
20.

Statistical practice in high-throughput screening data analysis.

Malo N, Hanley JA, Cerquozzi S, Pelletier J, Nadon R.

Nat Biotechnol. 2006 Feb;24(2):167-75.

PMID:
16465162

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