PubMed (cited) for id: 601232

Year	Number of Results
1995	1
2000	5
2001	2
2002	3
2003	3
2004	2
2005	2
2006	1
2007	1
2016	2
2019	1
2020	1
2024	0

1

Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation.

Thian M, Hoeger B, Kamnev A, Poyer F, Köstel Bal S, Caldera M, Jiménez-Heredia R, Huemer J, Pickl WF, Groß M, Ehl S, Lucas CL, Menche J, Hutter C, Attarbaschi A, Dupré L, Boztug K. Thian M, et al. Haematologica. 2020 Oct 1;105(10):e488. doi: 10.3324/haematol.2019.231399. Haematologica. 2020. PMID: 33054089 Free PMC article. No abstract available.

2

Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology.

Takeda AJ, Maher TJ, Zhang Y, Lanahan SM, Bucklin ML, Compton SR, Tyler PM, Comrie WA, Matsuda M, Olivier KN, Pittaluga S, McElwee JJ, Long Priel DA, Kuhns DB, Williams RL, Mustillo PJ, Wymann MP, Koneti Rao V, Lucas CL. Takeda AJ, et al. Nat Commun. 2019 Sep 25;10(1):4364. doi: 10.1038/s41467-019-12311-5. Nat Commun. 2019. PMID: 31554793 Free PMC article.

3

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.

De Henau O, Rausch M, Winkler D, Campesato LF, Liu C, Cymerman DH, Budhu S, Ghosh A, Pink M, Tchaicha J, Douglas M, Tibbitts T, Sharma S, Proctor J, Kosmider N, White K, Stern H, Soglia J, Adams J, Palombella VJ, McGovern K, Kutok JL, Wolchok JD, Merghoub T. De Henau O, et al. Nature. 2016 Nov 17;539(7629):443-447. doi: 10.1038/nature20554. Epub 2016 Nov 9. Nature. 2016. PMID: 27828943 Free PMC article.

4

PI3Kγ is a molecular switch that controls immune suppression.

Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA. Kaneda MM, et al. Nature. 2016 Nov 17;539(7629):437-442. doi: 10.1038/nature19834. Epub 2016 Sep 19. Nature. 2016. PMID: 27642729 Free PMC article.

5

PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasis.

Hawkins PT, Stephens LR. Hawkins PT, et al. Science. 2007 Oct 5;318(5847):64-6. doi: 10.1126/science.1145420. Science. 2007. PMID: 17916723

6

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.

Zhao M, Song B, Pu J, Wada T, Reid B, Tai G, Wang F, Guo A, Walczysko P, Gu Y, Sasaki T, Suzuki A, Forrester JV, Bourne HR, Devreotes PN, McCaig CD, Penninger JM. Zhao M, et al. Nature. 2006 Jul 27;442(7101):457-60. doi: 10.1038/nature04925. Nature. 2006. PMID: 16871217

7

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Camps M, et al. Nat Med. 2005 Sep;11(9):936-43. doi: 10.1038/nm1284. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127437 Free article.

8

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus.

Barber DF, Bartolomé A, Hernandez C, Flores JM, Redondo C, Fernandez-Arias C, Camps M, Rückle T, Schwarz MK, Rodríguez S, Martinez-A C, Balomenos D, Rommel C, Carrera AC. Barber DF, et al. Nat Med. 2005 Sep;11(9):933-5. doi: 10.1038/nm1291. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127435 Free article.

9

Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice.

Del Prete A, Vermi W, Dander E, Otero K, Barberis L, Luini W, Bernasconi S, Sironi M, Santoro A, Garlanda C, Facchetti F, Wymann MP, Vecchi A, Hirsch E, Mantovani A, Sozzani S. Del Prete A, et al. EMBO J. 2004 Sep 1;23(17):3505-15. doi: 10.1038/sj.emboj.7600361. Epub 2004 Aug 19. EMBO J. 2004. PMID: 15318168 Free PMC article.

10

PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.

Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, Silengo L, Altruda F, Wetzker R, Wymann MP, Lembo G, Hirsch E. Patrucco E, et al. Cell. 2004 Aug 6;118(3):375-87. doi: 10.1016/j.cell.2004.07.017. Cell. 2004. PMID: 15294162 Free article.

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