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Items: 1 to 20 of 70

1.

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.

Choo HJ, Cutler A, Pavlath GK.

Stem Cells. 2016 Jul 19. doi: 10.1002/stem.2467. [Epub ahead of print]

PMID:
27434733
2.

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.

Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterlé S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L.

EMBO J. 2016 May 17;35(10):1077-97. doi: 10.15252/embj.201592559.

3.

Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes.

Kang K, Nam S, Kim B, Lim JH, Yang Y, Lee MS, Lim JS.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):611-6. doi: 10.1016/j.bbrc.2015.10.167.

PMID:
26546825
4.

The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility.

Tang F, Gill J, Ficht X, Barthlott T, Cornils H, Schmitz-Rohmer D, Hynx D, Zhou D, Zhang L, Xue G, Grzmil M, Yang Z, Hergovich A, Hollaender GA, Stein JV, Hemmings BA, Matthias P.

Sci Signal. 2015 Oct 6;8(397):ra100. doi: 10.1126/scisignal.aab2425.

PMID:
26443704
5.

NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development.

Schmitz-Rohmer D, Probst S, Yang ZZ, Laurent F, Stadler MB, Zuniga A, Zeller R, Hynx D, Hemmings BA, Hergovich A.

PLoS One. 2015 Aug 25;10(8):e0136566. doi: 10.1371/journal.pone.0136566.

6.

The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.

Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.

Cell Signal. 2015 Oct;27(10):2087-98. doi: 10.1016/j.cellsig.2015.07.012.

PMID:
26208882
7.

Uterine NDRG2 expression is increased at implantation sites during early pregnancy in mice, and its down-regulation inhibits decidualization of mouse endometrial stromal cells.

Gu Y, Zhang X, Yang Q, Wang JM, He YP, Sun ZG, Zhang HQ, Wang J.

Reprod Biol Endocrinol. 2015 May 27;13:49. doi: 10.1186/s12958-015-0047-7. Erratum in: Reprod Biol Endocrinol. 2015;13:98.

8.

A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth.

Lin C, Yao E, Chuang PT.

Dev Biol. 2015 Jul 1;403(1):101-13. doi: 10.1016/j.ydbio.2015.04.014.

9.

The E3 ubiquitin ligase TRIM32 regulates myoblast proliferation by controlling turnover of NDRG2.

Mokhonova EI, Avliyakulov NK, Kramerova I, Kudryashova E, Haykinson MJ, Spencer MJ.

Hum Mol Genet. 2015 May 15;24(10):2873-83. doi: 10.1093/hmg/ddv049.

10.

ZIP2 protein, a zinc transporter, is associated with keratinocyte differentiation.

Inoue Y, Hasegawa S, Ban S, Yamada T, Date Y, Mizutani H, Nakata S, Tanaka M, Hirashima N.

J Biol Chem. 2014 Aug 1;289(31):21451-62. doi: 10.1074/jbc.M114.560821.

11.

Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway.

Yang R, Kong E, Jin J, Hergovich A, Püschel AW.

J Cell Sci. 2014 Aug 15;127(Pt 16):3463-76. doi: 10.1242/jcs.146696.

12.

The serine/threonine kinase Ndr2 controls integrin trafficking and integrin-dependent neurite growth.

Rehberg K, Kliche S, Madencioglu DA, Thiere M, Müller B, Meineke BM, Freund C, Budinger E, Stork O.

J Neurosci. 2014 Apr 9;34(15):5342-54. doi: 10.1523/JNEUROSCI.2728-13.2014.

13.

Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury.

Takarada-Iemata M, Kezuka D, Takeichi T, Ikawa M, Hattori T, Kitao Y, Hori O.

J Neurochem. 2014 Aug;130(3):374-87. doi: 10.1111/jnc.12729.

14.

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers.

Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, Manachai N, Yamakawa N, Hamasaki M, Kitabayashi I, Arai Y, Kanai Y, Taki T, Abe T, Kiyonari H, Shimoda K, Ohshima K, Horii A, Shima H, Taniwaki M, Yamaguchi R, Morishita K.

Nat Commun. 2014 Feb 26;5:3393. doi: 10.1038/ncomms4393.

15.

Electroacupuncture attenuates reference memory impairment associated with astrocytic NDRG2 suppression in APP/PS1 transgenic mice.

Wang F, Zhong H, Li X, Peng Y, Kinden R, Liang W, Li X, Shi M, Liu L, Wang Q, Xiong L.

Mol Neurobiol. 2014 Oct;50(2):305-13. doi: 10.1007/s12035-013-8609-1.

PMID:
24390566
16.

Ndrg2 is a PGC-1α/ERRα target gene that controls protein synthesis and expression of contractile-type genes in C2C12 myotubes.

Foletta VC, Brown EL, Cho Y, Snow RJ, Kralli A, Russell AP.

Biochim Biophys Acta. 2013 Dec;1833(12):3112-23. doi: 10.1016/j.bbamcr.2013.08.011.

17.

NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15.

Chiba S, Amagai Y, Homma Y, Fukuda M, Mizuno K.

EMBO J. 2013 Mar 20;32(6):874-85. doi: 10.1038/emboj.2013.32.

18.

FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.

Deuschle U, Schüler J, Schulz A, Schlüter T, Kinzel O, Abel U, Kremoser C.

PLoS One. 2012;7(10):e43044. doi: 10.1371/journal.pone.0043044.

19.

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM.

Front Neurosci. 2012 Sep 12;6:130. doi: 10.3389/fnins.2012.00130.

20.

Ndrg2 regulates vertebral specification in differentiating somites.

Zhu H, Zhao J, Zhou W, Li H, Zhou R, Zhang L, Zhao H, Cao J, Zhu X, Hu H, Ma G, He L, Yao Z, Yao L, Guo X.

Dev Biol. 2012 Sep 15;369(2):308-18. doi: 10.1016/j.ydbio.2012.07.001.

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