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Items: 1 to 20 of 394

1.

Interactions between 5-Lipoxygenase Polymorphisms and Adipose Tissue Contents of Arachidonic and Eicosapentaenoic Acids Do Not Affect Risk of Myocardial Infarction in Middle-Aged Men and Women in a Danish Case-Cohort Study.

Gammelmark A, Lundbye-Christensen S, Tjønneland A, Schmidt EB, Overvad K, Nielsen MS.

J Nutr. 2017 Jul;147(7):1340-1347. doi: 10.3945/jn.117.247569. Epub 2017 May 31.

PMID:
28566527
2.

Architecture of the human interactome defines protein communities and disease networks.

Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW.

Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.

3.

Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.

Ball AK, Beilstein K, Wittmann S, Sürün D, Saul MJ, Schnütgen F, Flamand N, Capelo R, Kahnt AS, Frey H, Schaefer L, Marschalek R, Häfner AK, Steinhilber D.

Biochim Biophys Acta. 2017 May;1862(5):561-571. doi: 10.1016/j.bbalip.2017.02.015. Epub 2017 Feb 28.

PMID:
28257804
4.

Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.

Li C, Wang D, Lv X, Jing R, Bi B, Chen X, Guo J, Wang F, Sun S, Azadzoi KM, Yang JH.

Cell Cycle. 2017 Apr 3;16(7):649-659. doi: 10.1080/15384101.2017.1281481. Epub 2017 Jan 19.

PMID:
28103160
5.

Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.

Gammelmark A, Nielsen MS, Lundbye-Christensen S, Tjønneland A, Schmidt EB, Overvad K.

PLoS One. 2016 Nov 28;11(11):e0167217. doi: 10.1371/journal.pone.0167217. eCollection 2016.

6.

Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase.

Häfner AK, Beilstein K, Graab P, Ball AK, Saul MJ, Hofmann B, Steinhilber D.

PLoS One. 2016 Nov 17;11(11):e0166591. doi: 10.1371/journal.pone.0166591. eCollection 2016.

7.

The Salmonella Effector SteD Mediates MARCH8-Dependent Ubiquitination of MHC II Molecules and Inhibits T Cell Activation.

Bayer-Santos E, Durkin CH, Rigano LA, Kupz A, Alix E, Cerny O, Jennings E, Liu M, Ryan AS, Lapaque N, Kaufmann SHE, Holden DW.

Cell Host Microbe. 2016 Nov 9;20(5):584-595. doi: 10.1016/j.chom.2016.10.007.

8.

Alox5 Blockade Eradicates JAK2V617F-Induced Polycythemia Vera in Mice.

Chen Y, Shan Y, Lu M, DeSouza N, Guo Z, Hoffman R, Liang A, Li S.

Cancer Res. 2017 Jan 1;77(1):164-174. doi: 10.1158/0008-5472.CAN-15-2933. Epub 2016 Oct 26.

PMID:
27784744
9.

A Novel Inhibitor of 5-Lipoxygenase (5-LOX) Prevents Oxidative Stress-Induced Cell Death of Retinal Pigment Epithelium (RPE) Cells.

Subramanian P, Mendez EF, Becerra SP.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4581-8. doi: 10.1167/iovs.15-19039.

10.

Major Histocompatibility Complex Class II HLA-DRα Is Downregulated by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Lytic Transactivator RTA and MARCH8.

Sun Z, Jha HC, Pei YG, Robertson ES.

J Virol. 2016 Aug 26;90(18):8047-58. doi: 10.1128/JVI.01079-16. Print 2016 Sep 15.

11.

Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase.

Joshi V, Umashankara M, Ramakrishnan C, Nanjaraj Urs AN, Suvilesh KN, Velmurugan D, Rangappa KS, Vishwanath BS.

Arch Biochem Biophys. 2016 May 15;598:28-39. doi: 10.1016/j.abb.2016.04.003. Epub 2016 Apr 6.

PMID:
27060751
12.

5-Lipoxygenase Gene Variants Are Not Associated With Atherosclerosis or Incident Coronary Heart Disease in the Multi-Ethnic Study of Atherosclerosis Cohort.

Tsai MY, Cao J, Steffen BT, Weir NL, Rich SS, Liang S, Guan W.

J Am Heart Assoc. 2016 Mar 29;5(3):e002814. doi: 10.1161/JAHA.115.002814.

13.

Copy number variation in ALOX5 and PTGER1 is associated with NSAIDs-induced urticaria and/or angioedema.

Plaza-Serón Mdel C, Ayuso P, Pérez-Sánchez N, Doña I, Blanca-Lopez N, Flores C, Galindo L, Molina A, Perkins JR, Cornejo-García JA, Agúndez JA, García-Martín E, Campo P, Canto G, Blanca M.

Pharmacogenet Genomics. 2016 Jun;26(6):280-7. doi: 10.1097/FPC.0000000000000216.

PMID:
26959713
14.

Arachidonate 5-lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index.

Šerý O, Hlinecká L, Povová J, Bonczek O, Zeman T, Janout V, Ambroz P, Khan NA, Balcar VJ.

J Neurol Sci. 2016 Mar 15;362:27-32. doi: 10.1016/j.jns.2016.01.022. Epub 2016 Jan 15.

PMID:
26944113
15.

Cell differentiation and the multiple drug resistance phenotype in human erythroleukemic cells.

Carrett-Dias M, Almeida LK, Pereira JL, Almeida DV, Filgueira DM, Marins LF, Votto AP, Trindade GS.

Leuk Res. 2016 Mar;42:13-20. doi: 10.1016/j.leukres.2016.01.008. Epub 2016 Jan 21.

16.

5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation.

Gerstmeier J, Newcomer ME, Dennhardt S, Romp E, Fischer J, Werz O, Garscha U.

FASEB J. 2016 May;30(5):1892-900. doi: 10.1096/fj.201500210R. Epub 2016 Feb 3.

17.

Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro.

Che XH, Chen CL, Ye XL, Weng GB, Guo XZ, Yu WY, Tao J, Chen YC, Chen X.

Oncol Rep. 2016 Mar;35(3):1680-8. doi: 10.3892/or.2015.4506. Epub 2015 Dec 22.

PMID:
26707712
18.

MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins.

Tada T, Zhang Y, Koyama T, Tobiume M, Tsunetsugu-Yokota Y, Yamaoka S, Fujita H, Tokunaga K.

Nat Med. 2015 Dec;21(12):1502-7. doi: 10.1038/nm.3956. Epub 2015 Nov 2.

PMID:
26523972
19.

Genetic polymorphisms in very important pharmacogenomic (VIP) variants in the Tibetan population.

Jin TB, Xun XJ, Shi XG, Yuan DY, Feng T, Geng TT, Kang LL.

Genet Mol Res. 2015 Oct 16;14(4):12497-504. doi: 10.4238/2015.October.16.17.

20.

Identification of the Substrate Access Portal of 5-Lipoxygenase.

Mitra S, Bartlett SG, Newcomer ME.

Biochemistry. 2015 Oct 20;54(41):6333-42. doi: 10.1021/acs.biochem.5b00930. Epub 2015 Oct 8.

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