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Cyclin-dependent kinase 5 activity is required for allogeneic T-cell responses after hematopoietic cell transplantation in mice.

Askew D, Pareek TK, Eid S, Ganguly S, Tyler M, Huang AY, Letterio JJ, Cooke KR.

Blood. 2017 Jan 12;129(2):246-256. doi: 10.1182/blood-2016-05-702738.


IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells.

Yang R, Masters AR, Fortner KA, Champagne DP, Yanguas-Casás N, Silberger DJ, Weaver CT, Haynes L, Rincon M.

J Exp Med. 2016 Oct 17;213(11):2281-2291.


High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium.; Jackson Laboratory.; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS).; Charles River Laboratories.; MRC Harwell.; Toronto Centre for Phenogenomics.; Wellcome Trust Sanger Institute.; RIKEN BioResource Center., MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14.


[Down-regulation of TIPE2 promotes the proliferation and immune activity of T lymphocytes].

Huang L, Chen J, Hong B.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016 Jul;32(7):886-90. Chinese.


The Antitumor Effect of Gekko Sulfated Glycopeptide by Inhibiting bFGF-Induced Lymphangiogenesis.

Ding XL, Man YN, Hao J, Zhu CH, Liu C, Yang X, Wu XZ.

Biomed Res Int. 2016;2016:7396392. doi: 10.1155/2016/7396392.


EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells.

Li J, Lu E, Yi T, Cyster JG.

Nature. 2016 May 5;533(7601):110-4. doi: 10.1038/nature17947.


Interleukin-21 expression in hippocampal astrocytes is enhanced following kainic acid-induced seizures.

Xiong XY, Wang TG, Yang MH, Meng ZY, Yang QW, Wang FX.

Neurol Res. 2016 Feb;38(2):151-7. doi: 10.1080/01616412.2015.1135557.


Interleukin-21 administration leads to enhanced antigen-specific T cell responses and natural killer cells in HIV-1 vaccinated mice.

Ju B, Li D, Ji X, Liu J, Peng H, Wang S, Liu Y, Hao Y, Yee C, Liang H, Shao Y.

Cell Immunol. 2016 May;303:55-65. doi: 10.1016/j.cellimm.2016.03.006.


Different Concentrations of FGF Ligands, FGF2 or FGF8 Determine Distinct States of WNT-Induced Presomitic Mesoderm.

Sudheer S, Liu J, Marks M, Koch F, Anurin A, Scholze M, Senft AD, Wittler L, Macura K, Grote P, Herrmann BG.

Stem Cells. 2016 Jul;34(7):1790-800. doi: 10.1002/stem.2371.


Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.

Smith GA, Uchida K, Weiss A, Taunton J.

Nat Chem Biol. 2016 May;12(5):373-9. doi: 10.1038/nchembio.2056.


[Regulatory T-cells in systemic lupus erythematosus. IL-2 is decisive for loss of tolerance].

Ohl K, Tenbrock K.

Z Rheumatol. 2016 Apr;75(3):253-64. doi: 10.1007/s00393-016-0060-z. Review. German.


Modulation of intracellular expression of IFNγ and IL-2 in culture of splenic T lymphocytes by some flavonoid glycosides of Alchornea floribunda.

Okoye FB, Odimegwu DC, Nworu CS, Agbo MO, Esimone CO, Osadebe PO, Proksch P.

Pharm Biol. 2016 Sep;54(9):1873-80. doi: 10.3109/13880209.2015.1133659.


FGF-2 deficiency causes dysregulation of Arhgef6 and downstream targets in the cerebral cortex accompanied by altered neurite outgrowth and dendritic spine morphology.

Baum P, Vogt MA, Gass P, Unsicker K, von Bohlen und Halbach O.

Int J Dev Neurosci. 2016 May;50:55-64. doi: 10.1016/j.ijdevneu.2016.03.002.


A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

Xin A, Masson F, Liao Y, Preston S, Guan T, Gloury R, Olshansky M, Lin JX, Li P, Speed TP, Smyth GK, Ernst M, Leonard WJ, Pellegrini M, Kaech SM, Nutt SL, Shi W, Belz GT, Kallies A.

Nat Immunol. 2016 Apr;17(4):422-32. doi: 10.1038/ni.3410.


A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets.

Tian Y, Cox MA, Kahan SM, Ingram JT, Bakshi RK, Zajac AJ.

J Immunol. 2016 Mar 1;196(5):2153-66. doi: 10.4049/jimmunol.1401236.


Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.

Chien SY, Huang CY, Tsai CH, Wang SW, Lin YM, Tang CH.

Clin Sci (Lond). 2016 May;130(9):667-81. doi: 10.1042/CS20150622.


CTL-Promoting Effects of IL-21 Counteract Murine Lupus in the Parent→F1 Graft-versus-Host Disease Model.

Nguyen V, Rus H, Chen C, Rus V.

J Immunol. 2016 Feb 15;196(4):1529-40. doi: 10.4049/jimmunol.1501824.


Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z.

Biol Reprod. 2016 Feb;94(2):41. doi: 10.1095/biolreprod.115.136358.


Expression of FGFs during early mouse tongue development.

Du W, Prochazka J, Prochazkova M, Klein OD.

Gene Expr Patterns. 2016 Mar;20(2):81-7. doi: 10.1016/j.gep.2015.12.003.


Role of epithelial ion transports in inflammatory bowel disease.

Magalhães D, Cabral JM, Soares-da-Silva P, Magro F.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G460-76. doi: 10.1152/ajpgi.00369.2015. Review.


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