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Items: 1 to 20 of 137

1.

Architecture of the human interactome defines protein communities and disease networks.

Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW.

Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.

2.

GAB2 rs2373115 variant contributes to Alzheimer's disease risk specifically in European population.

Hu Y, Zheng L, Cheng L, Zhang Y, Bai W, Zhou W, Wang T, Han Z, Zong J, Jin S, Zhang J, Liu G, Jiang Q.

J Neurol Sci. 2017 Apr 15;375:18-22. doi: 10.1016/j.jns.2017.01.030. Epub 2017 Jan 10.

PMID:
28320126
3.

YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway.

Wang C, Gu C, Jeong KJ, Zhang D, Guo W, Lu Y, Ju Z, Panupinthu N, Yang JY, Gagea MM, Ng PK, Zhang F, Mills GB.

Cancer Res. 2017 Apr 1;77(7):1637-1648. doi: 10.1158/0008-5472.CAN-15-3084. Epub 2017 Feb 15.

PMID:
28202507
4.

Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.

Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP.

Mol Cell Biol. 2017 Mar 17;37(7). pii: e00357-16. doi: 10.1128/MCB.00357-16. Print 2017 Apr 1.

PMID:
28096188
5.

MicroRNA-302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma.

Ma J, Yu J, Liu J, Yang X, Lou M, Liu J, Feng F, Ji P, Wang L.

Oncol Rep. 2017 Feb;37(2):1159-1167. doi: 10.3892/or.2016.5320. Epub 2016 Dec 15.

PMID:
28000880
6.

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B.

Cell Res. 2016 Dec;26(12):1302-1319. doi: 10.1038/cr.2016.125. Epub 2016 Nov 1.

PMID:
27801882
7.

Expression Pattern and Clinical Significance of Gab2 Protein in Hepatocellular Carcinoma.

Hu X, He B, Zhou L, Xie H, Zheng S.

Clin Lab. 2016;62(6):1087-92.

8.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R; UK10K Rare Diseases Group.

Nat Commun. 2016 May 13;7:11491. doi: 10.1038/ncomms11491.

9.

MicroRNA-197 inhibits cell proliferation by targeting GAB2 in glioblastoma.

Tian LQ, Liu EQ, Zhu XD, Wang XG, Li J, Xu GM.

Mol Med Rep. 2016 May;13(5):4279-88. doi: 10.3892/mmr.2016.5076. Epub 2016 Mar 31.

PMID:
27035789
10.

GAB2 promotes cell proliferation by activating the ERK signaling pathway in hepatocellular carcinoma.

Chen Y, Liu Q, Wu M, Li M, Ding H, Shan X, Liu J, Tao T, Ni R, Chen X.

Tumour Biol. 2016 Sep;37(9):11763-11773. Epub 2016 Mar 30.

PMID:
27026230
11.

Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.

Osinalde N, Sánchez-Quiles V, Blagoev B, Kratchmarova I.

Sci Rep. 2016 Mar 30;6:23530. doi: 10.1038/srep23530.

12.

Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer.

Ding C, Luo J, Li L, Li S, Yang L, Pan H, Liu Q, Qin H, Chen C, Feng J.

J Exp Clin Cancer Res. 2016 Jan 12;35:5. doi: 10.1186/s13046-015-0280-0.

13.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

Kırlı K, Karaca S, Dehne HJ, Samwer M, Pan KT, Lenz C, Urlaub H, Görlich D.

Elife. 2015 Dec 17;4. pii: e11466. doi: 10.7554/eLife.11466.

14.

Grb2-associated binder 2 silencing impairs growth and migration of H1975 cells via modulation of PI3K-Akt signaling.

Wang WJ, Mou K, Wu XF, Zhang JZ, Ren G, Qi JD, Xu YF, Yao X.

Int J Clin Exp Pathol. 2015 Sep 1;8(9):10575-84. eCollection 2015.

15.

Identification of four new susceptibility loci for testicular germ cell tumour.

Litchfield K, Holroyd A, Lloyd A, Broderick P, Nsengimana J, Eeles R, Easton DF, Dudakia D, Bishop DT, Reid A, Huddart RA, Grotmol T, Wiklund F, Shipley J, Houlston RS, Turnbull C.

Nat Commun. 2015 Oct 27;6:8690. doi: 10.1038/ncomms9690.

16.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

17.

Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b.

Yang L, Ma Y, Han W, Li W, Cui L, Zhao X, Tian Y, Zhou Z, Wang W, Wang H.

J Biol Chem. 2015 Oct 30;290(44):26627-37. doi: 10.1074/jbc.M115.667717. Epub 2015 Sep 9.

18.

USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2.

Liu C, Wang L, Chen W, Zhao S, Yin C, Lin Y, Jiang A, Zhang P.

Oncotarget. 2015 Sep 29;6(29):27891-906. doi: 10.18632/oncotarget.4451.

19.

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP.

Cell. 2015 Jul 16;162(2):425-40. doi: 10.1016/j.cell.2015.06.043.

20.

Gab2 is a novel prognostic factor for colorectal cancer patients.

Ding C, Luo J, Yu W, Gao S, Yang L, Chen C, Feng J.

Int J Clin Exp Pathol. 2015 Mar 1;8(3):2779-86. eCollection 2015.

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