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Items: 1 to 20 of 78

1.

Derlin-1 promotes ubiquitylation and degradation of the epithelial Na+ channel, ENaC.

You H, Ge Y, Zhang J, Cao Y, Xing J, Su D, Huang Y, Li M, Qu S, Sun F, Liang X.

J Cell Sci. 2017 Mar 15;130(6):1027-1036. doi: 10.1242/jcs.198242. Epub 2017 Jan 30.

2.

Thermodynamics of the Purine Nucleoside Phosphorylase Reaction Revealed by Computer Simulations.

Isaksen GV, Åqvist J, Brandsdal BO.

Biochemistry. 2017 Jan 10;56(1):306-312. doi: 10.1021/acs.biochem.6b00967. Epub 2016 Dec 27.

PMID:
27976868
3.

Computer Simulations Reveal Substrate Specificity of Glycosidic Bond Cleavage in Native and Mutant Human Purine Nucleoside Phosphorylase.

Isaksen GV, Hopmann KH, Åqvist J, Brandsdal BO.

Biochemistry. 2016 Apr 12;55(14):2153-62. doi: 10.1021/acs.biochem.5b01347. Epub 2016 Mar 29.

PMID:
26985580
4.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

5.

Panorama of ancient metazoan macromolecular complexes.

Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, Tillier ER, Wallingford JB, Parkinson J, Marcotte EM, Emili A.

Nature. 2015 Sep 17;525(7569):339-44. doi: 10.1038/nature14877. Epub 2015 Sep 7.

6.

Isotope-specific and amino acid-specific heavy atom substitutions alter barrier crossing in human purine nucleoside phosphorylase.

Suarez J, Schramm VL.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11247-51. doi: 10.1073/pnas.1513956112. Epub 2015 Aug 24.

7.

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

Drissi R, Dubois ML, Douziech M, Boisvert FM.

Mol Cell Proteomics. 2015 Jul;14(7):2002-13. doi: 10.1074/mcp.M115.048991. Epub 2015 May 11.

8.

Phospho-tyrosine dependent protein-protein interaction network.

Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U.

Mol Syst Biol. 2015 Mar 26;11(3):794. doi: 10.15252/msb.20145968.

9.

ABCE1 is a highly conserved RNA silencing suppressor.

Kärblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, Kylsten P, Ekwall K, Swoboda P, Truve E, Sarmiento C.

PLoS One. 2015 Feb 6;10(2):e0116702. doi: 10.1371/journal.pone.0116702. eCollection 2015.

10.

The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning.

Decherchi S, Berteotti A, Bottegoni G, Rocchia W, Cavalli A.

Nat Commun. 2015 Jan 27;6:6155. doi: 10.1038/ncomms7155.

11.

A proteome-scale map of the human interactome network.

Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Trigg SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M.

Cell. 2014 Nov 20;159(5):1212-1226. doi: 10.1016/j.cell.2014.10.050.

12.

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

Kariuki SN, Ghodke-Puranik Y, Dorschner JM, Chrabot BS, Kelly JA, Tsao BP, Kimberly RP, Alarcón-Riquelme ME, Jacob CO, Criswell LA, Sivils KL, Langefeld CD, Harley JB, Skol AD, Niewold TB.

Genes Immun. 2015 Jan-Feb;16(1):15-23. doi: 10.1038/gene.2014.57. Epub 2014 Oct 23.

13.

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

Roy R, Durie D, Li H, Liu BQ, Skehel JM, Mauri F, Cuorvo LV, Barbareschi M, Guo L, Holcik M, Seckl MJ, Pardo OE.

Nucleic Acids Res. 2014 Nov 10;42(20):12483-97. doi: 10.1093/nar/gku953. Epub 2014 Oct 16.

14.

AS3MT, GSTO, and PNP polymorphisms: impact on arsenic methylation and implications for disease susceptibility.

Antonelli R, Shao K, Thomas DJ, Sams R 2nd, Cowden J.

Environ Res. 2014 Jul;132:156-67. doi: 10.1016/j.envres.2014.03.012. Epub 2014 May 8. Review.

PMID:
24792412
15.

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

Lu L, Hu S, Wei R, Qiu X, Lu K, Fu Y, Li H, Xing G, Li D, Peng R, He F, Zhang L.

J Biol Chem. 2013 Dec 13;288(50):35637-50. doi: 10.1074/jbc.M113.472076. Epub 2013 Oct 25.

16.

Functional analysis of purine nucleoside phosphorylase as a key enzyme in ribavirin metabolism.

Furihata T, Kishida S, Sugiura H, Kamiichi A, Iikura M, Chiba K.

Drug Metab Pharmacokinet. 2014;29(2):211-4. Epub 2013 Oct 8.

17.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.

Proteomics. 2013 May;13(10-11):1667-1671. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.

18.

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.

Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S.

J Proteomics. 2013 Apr 26;82:193-229. doi: 10.1016/j.jprot.2013.01.012. Epub 2013 Jan 30.

PMID:
23376485
19.

A census of human soluble protein complexes.

Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A.

Cell. 2012 Aug 31;150(5):1068-81. doi: 10.1016/j.cell.2012.08.011.

20.

A high-throughput approach for measuring temporal changes in the interactome.

Kristensen AR, Gsponer J, Foster LJ.

Nat Methods. 2012 Sep;9(9):907-9. doi: 10.1038/nmeth.2131. Epub 2012 Aug 5.

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