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Items: 1 to 20 of 1199

1.

Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.

Lin Y, Henderson P, Pettersson S, Satsangi J, Hupp T, Stevens C.

FEBS J. 2011 Jan;278(2):354-70. doi: 10.1111/j.1742-4658.2010.07959.x. Epub 2010 Dec 6.

3.

The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition.

Shiono M, Kobayashi T, Takahashi R, Sun G, Abe M, Zhang D, Wang L, Piao X, Takagi Y, Mineki R, Taka H, Tada N, Sonobe S, Momose S, Ueda M, Hino O.

Oncogene. 2008 Nov 6;27(52):6690-7. doi: 10.1038/onc.2008.283. Epub 2008 Aug 11.

PMID:
18695678
4.
5.

Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.

Yoon HS, Ramachandiran S, Chacko MA, Monks TJ, Lau SS.

Am J Physiol Renal Physiol. 2004 Feb;286(2):F417-24. Epub 2003 Nov 11.

6.

The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.

Li Y, Inoki K, Vacratsis P, Guan KL.

J Biol Chem. 2003 Apr 18;278(16):13663-71. Epub 2003 Feb 11.

7.

Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.

Cai S, Everitt JI, Kugo H, Cook J, Kleymenova E, Walker CL.

Am J Pathol. 2003 Feb;162(2):457-68.

8.

Aberrant splicing in several human tumors in the tumor suppressor genes neurofibromatosis type 1, neurofibromatosis type 2, and tuberous sclerosis 2.

Kaufmann D, Leistner W, Kruse P, Kenner O, Hoffmeyer S, Hein C, Vogel W, Messiaen L, Bartelt B.

Cancer Res. 2002 Mar 1;62(5):1503-9.

10.

The tuberous sclerosis 2 gene product can localize to nuclei in a phosphorylation-dependent manner.

Lou D, Griffith N, Noonan DJ.

Mol Cell Biol Res Commun. 2001 Nov;4(6):374-80.

PMID:
11703097
11.
12.

Mutation and polymorphism analysis in the tuberous sclerosis 2 (TSC2) gene.

Gilbert JR, Guy V, Kumar A, Wolpert C, Kandt R, Aylesworth A, Roses AD, Pericak-Vance MA.

Neurogenetics. 1998 Aug;1(4):267-72.

PMID:
10732801
13.

Novel intragenic polymorphisms in the tuberous sclerosis 2 (TSC2) gene. Mutations in brief no. 184. Online.

Astrinidis A, Kouvatsi A, Nahmias J, Povey S, Pandeliadis C, Danzaki A, Schneider M, Triantaphyllidis C.

Hum Mutat. 1998;12(3):217.

PMID:
10660335
14.

Genetic variants of the tuberous sclerosis 2 tumour suppressor gene in mouse t haplotypes.

Kleymenova EV, Declue JE, Walker CL.

Genet Res. 1999 Oct;74(2):139-44.

PMID:
10584558
15.

Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development.

Rennebeck G, Kleymenova EV, Anderson R, Yeung RS, Artzt K, Walker CL.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15629-34.

16.

Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homolog.

Kobayashi T, Urakami S, Cheadle JP, Aspinwall R, Harris P, Sampson JR, Hino O.

Mamm Genome. 1997 Aug;8(8):554-8.

PMID:
9250859
17.

A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas.

Platten M, Meyer-Puttlitz B, Blümcke I, Waha A, Wolf HK, Nöthen MM, Louis DN, Sampson JR, von Deimling A.

J Neuropathol Exp Neurol. 1997 Jul;56(7):806-10.

PMID:
9210877
18.

Expression of the tuberous sclerosis 2 gene product, tuberin, in adult and developing nervous system tissues.

Geist RT, Reddy AJ, Zhang J, Gutmann DH.

Neurobiol Dis. 1996 Apr;3(2):111-20.

PMID:
9173918
19.

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.

Xiao GH, Shoarinejad F, Jin F, Golemis EA, Yeung RS.

J Biol Chem. 1997 Mar 7;272(10):6097-100.

20.

Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.

Kerfoot C, Wienecke R, Menchine M, Emelin J, Maize JC Jr, Welsh CT, Norman MG, DeClue JE, Vinters HV.

Brain Pathol. 1996 Oct;6(4):367-75.

PMID:
8944308

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