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Items: 1 to 20 of 498

1.

[Detection of Bruton's tyrosine kinase gene mutations and clinical analysis of 6 patients with X-linked agammaglobulinemia].

Zhang X, Li H, Li Q, Gao J, Shi X.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2014 Feb;31(1):29-33. doi: 10.3760/cma.j.issn.1003-9406.2014.01.007. Chinese.

PMID:
24510558
2.

A novel Bruton's tyrosine kinase gene (BTK) invariant splice site mutation in a Malaysian family with X-linked agammaglobulinemia.

Chear CT, Gill HK, Ramly NH, Dhaliwal JS, Bujang N, Ripen AM, Mohamad SB.

Asian Pac J Allergy Immunol. 2013 Dec;31(4):320-4. doi: 10.12932/AP0304.31.4.2013.

3.

A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis.

Eifert C, Wang X, Kokabee L, Kourtidis A, Jain R, Gerdes MJ, Conklin DS.

Genes Chromosomes Cancer. 2013 Oct;52(10):961-75. doi: 10.1002/gcc.22091. Epub 2013 Aug 3.

4.

The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells.

Nündel K, Busto P, Debatis M, Marshak-Rothstein A.

J Leukoc Biol. 2013 Nov;94(5):865-75. doi: 10.1189/jlb.0313126. Epub 2013 Jun 26.

5.

Cross talk between peritoneal macrophages and B-1 cells in vitro.

Thies FG, Laurindo MF, Perez EC, Novaes e Brito RR, Mariano M, Popi AF.

PLoS One. 2013 May 8;8(5):e62805. doi: 10.1371/journal.pone.0062805. Print 2013.

6.

The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection.

Köprülü AD, Kastner R, Wienerroither S, Lassnig C, Putz EM, Majer O, Reutterer B, Sexl V, Kuchler K, Müller M, Decker T, Ellmeier W.

PLoS One. 2013;8(3):e60476. doi: 10.1371/journal.pone.0060476. Epub 2013 Mar 27.

7.

B1a cells enhance susceptibility to infection with virulent Francisella tularensis via modulation of NK/NKT cell responses.

Crane DD, Griffin AJ, Wehrly TD, Bosio CM.

J Immunol. 2013 Mar 15;190(6):2756-66. doi: 10.4049/jimmunol.1202697. Epub 2013 Feb 1.

8.

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.

Tai YT, Chang BY, Kong SY, Fulciniti M, Yang G, Calle Y, Hu Y, Lin J, Zhao JJ, Cagnetta A, Cea M, Sellitto MA, Zhong MY, Wang Q, Acharya C, Carrasco DR, Buggy JJ, Elias L, Treon SP, Matsui W, Richardson P, Munshi NC, Anderson KC.

Blood. 2012 Aug 30;120(9):1877-87. doi: 10.1182/blood-2011-12-396853. Epub 2012 Jun 11.

9.

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice.

Kil LP, de Bruijn MJ, van Nimwegen M, Corneth OB, van Hamburg JP, Dingjan GM, Thaiss F, Rimmelzwaan GF, Elewaut D, Delsing D, van Loo PF, Hendriks RW.

Blood. 2012 Apr 19;119(16):3744-56. doi: 10.1182/blood-2011-12-397919. Epub 2012 Mar 1.

10.

Consequences of two naturally occurring missense mutations in the structure and function of Bruton agammaglobulinemia tyrosine kinase.

Vargas-Hernández A, López-Herrera G, Maravillas-Montero JL, Vences-Catalán F, Mogica-Martínez D, Rojo-Domínguez A, Espinosa-Rosales FJ, Santos-Argumedo L.

IUBMB Life. 2012 Apr;64(4):346-53. doi: 10.1002/iub.1009. Epub 2012 Feb 29.

11.

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils.

Honda F, Kano H, Kanegane H, Nonoyama S, Kim ES, Lee SK, Takagi M, Mizutani S, Morio T.

Nat Immunol. 2012 Feb 26;13(4):369-78. doi: 10.1038/ni.2234.

PMID:
22366891
12.

Molecular characterization of Bruton's tyrosine kinase deficiency in 12 Iranian patients with presumed X-linked agammaglobulinemia.

Nasseri S, Sorouri R, Pourpak Z, Yeganeh M, Aghamohammadi A, Fiorini M, Shahkarami S, Mosallaei M, Rezaei N, Parvaneh N.

J Investig Allergol Clin Immunol. 2011;21(7):572-4. No abstract available.

13.

Clinical manifestations and BTK gene defect in 4 unrelated Taiwanese families with Bruton's disease.

Lee KH, Shyur SD, Chu SH, Huang LH, Kao YH, Lei WT, Cheng CH, Lo CY, Chen CK, Liu LC.

Asian Pac J Allergy Immunol. 2011 Sep;29(3):260-5.

14.

BTK gene mutation in two non-identical twins with X-linked agammaglobulinemia associated with polyarticular juvenile idiopathic arthritis.

Váncsa A, Tóth B, Szekanecz Z.

Isr Med Assoc J. 2011 Sep;13(9):579-80. No abstract available.

15.

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S, Flynn J, Jones J, Blum KA, Buggy JJ, Hamdy A, Johnson AJ, Byrd JC.

Blood. 2011 Jun 9;117(23):6287-96. doi: 10.1182/blood-2011-01-328484. Epub 2011 Mar 21.

16.

Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures.

Kuglstatter A, Wong A, Tsing S, Lee SW, Lou Y, Villaseñor AG, Bradshaw JM, Shaw D, Barnett JW, Browner MF.

Protein Sci. 2011 Feb;20(2):428-36. doi: 10.1002/pro.575.

17.

Role of Bruton's tyrosine kinase in macrophage apoptosis.

Khare A, Viswanathan B, Gund R, Jain N, Ravindran B, George A, Rath S, Bal V.

Apoptosis. 2011 Apr;16(4):334-46. doi: 10.1007/s10495-010-0569-6.

PMID:
21193961
18.

Neutrophil development and function critically depend on Bruton tyrosine kinase in a mouse model of X-linked agammaglobulinemia.

Fiedler K, Sindrilaru A, Terszowski G, Kokai E, Feyerabend TB, Bullinger L, Rodewald HR, Brunner C.

Blood. 2011 Jan 27;117(4):1329-39. doi: 10.1182/blood-2010-04-281170. Epub 2010 Nov 9.

19.

Clinical characteristics and molecular analysis of 21 Chinese children with congenital agammaglobulinemia.

Zhang ZY, Zhao XD, Jiang LP, Liu EM, Wang M, Yu J, Liu P, Yang XQ.

Scand J Immunol. 2010 Nov;72(5):454-9. doi: 10.1111/j.1365-3083.2010.02457.x.

20.

Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts.

Danks L, Workman S, Webster D, Horwood NJ.

J Bone Miner Res. 2011 Jan;26(1):182-92. doi: 10.1002/jbmr.210.

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