PubMed (GeneRIF) for id: 851099

Year	Number of Results
2004	1
2005	3
2006	3
2007	2
2009	3
2010	3
2011	2
2013	2
2014	3
2015	2
2016	1
2017	2
2018	2
2019	1
2020	2
2021	5
2022	2
2023	1
2024	0

1

The Smc5/6 complex is a DNA loop-extruding motor.

Pradhan B, Kanno T, Umeda Igarashi M, Loke MS, Baaske MD, Wong JSK, Jeppsson K, Björkegren C, Kim E. Pradhan B, et al. Nature. 2023 Apr;616(7958):843-848. doi: 10.1038/s41586-023-05963-3. Epub 2023 Apr 19. Nature. 2023. PMID: 37076626 Free PMC article.

2

Cryo-EM structure of the Smc5/6 holo-complex.

Hallett ST, Campbell Harry I, Schellenberger P, Zhou L, Cronin NB, Baxter J, Etheridge TJ, Murray JM, Oliver AW. Hallett ST, et al. Nucleic Acids Res. 2022 Sep 9;50(16):9505-9520. doi: 10.1093/nar/gkac692. Nucleic Acids Res. 2022. PMID: 35993814 Free PMC article.

3

Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.

Yu Y, Li S, Ser Z, Kuang H, Than T, Guan D, Zhao X, Patel DJ. Yu Y, et al. Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2202799119. doi: 10.1073/pnas.2202799119. Epub 2022 Jun 1. Proc Natl Acad Sci U S A. 2022. PMID: 35648833 Free PMC article.

4

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.

Taschner M, Basquin J, Steigenberger B, Schäfer IB, Soh YM, Basquin C, Lorentzen E, Räschle M, Scheltema RA, Gruber S. Taschner M, et al. EMBO J. 2021 Aug 2;40(15):e107807. doi: 10.15252/embj.2021107807. Epub 2021 Jun 30. EMBO J. 2021. PMID: 34191293 Free PMC article.

5

Smc5/6 in the rDNA modulates lifespan independently of Fob1.

Moradi-Fard S, Mojumdar A, Chan M, Harkness TAA, Cobb JA. Moradi-Fard S, et al. Aging Cell. 2021 Jun;20(6):e13373. doi: 10.1111/acel.13373. Epub 2021 May 12. Aging Cell. 2021. PMID: 33979898 Free PMC article.

6

Integrative analysis reveals unique structural and functional features of the Smc5/6 complex.

Yu Y, Li S, Ser Z, Sanyal T, Choi K, Wan B, Kuang H, Sali A, Kentsis A, Patel DJ, Zhao X. Yu Y, et al. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2026844118. doi: 10.1073/pnas.2026844118. Proc Natl Acad Sci U S A. 2021. PMID: 33941673 Free PMC article.

7

Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex.

Hallett ST, Schellenberger P, Zhou L, Beuron F, Morris E, Murray JM, Oliver AW. Hallett ST, et al. Nucleic Acids Res. 2021 May 7;49(8):4534-4549. doi: 10.1093/nar/gkab234. Nucleic Acids Res. 2021. PMID: 33849072 Free PMC article.

8

Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.

Agashe S, Joseph CR, Reyes TAC, Menolfi D, Giannattasio M, Waizenegger A, Szakal B, Branzei D. Agashe S, et al. Nat Commun. 2021 Apr 8;12(1):2111. doi: 10.1038/s41467-021-22217-w. Nat Commun. 2021. PMID: 33833229 Free PMC article.

9

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction.

Gutierrez-Escribano P, Hormeño S, Madariaga-Marcos J, Solé-Soler R, O'Reilly FJ, Morris K, Aicart-Ramos C, Aramayo R, Montoya A, Kramer H, Rappsilber J, Torres-Rosell J, Moreno-Herrero F, Aragon L. Gutierrez-Escribano P, et al. Mol Cell. 2020 Dec 17;80(6):1039-1054.e6. doi: 10.1016/j.molcel.2020.11.012. Epub 2020 Dec 9. Mol Cell. 2020. PMID: 33301732 Free PMC article.

10

Relocation of Collapsed Forks to the Nuclear Pore Complex Depends on Sumoylation of DNA Repair Proteins and Permits Rad51 Association.

Whalen JM, Dhingra N, Wei L, Zhao X, Freudenreich CH. Whalen JM, et al. Cell Rep. 2020 May 12;31(6):107635. doi: 10.1016/j.celrep.2020.107635. Cell Rep. 2020. PMID: 32402281 Free PMC article.

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