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Beauvericin inhibits melanogenesis by regulating cAMP/PKA/CREB and LXR-α/p38 MAPK-mediated pathways.

Lee SE, Park SH, Oh SW, Yoo JA, Kwon K, Park SJ, Kim J, Lee HS, Cho JY, Lee J.

Sci Rep. 2018 Oct 8;8(1):14958. doi: 10.1038/s41598-018-33352-8.


Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.

Gao X, Tao Y, Lamas V, Huang M, Yeh WH, Pan B, Hu YJ, Hu JH, Thompson DB, Shu Y, Li Y, Wang H, Yang S, Xu Q, Polley DB, Liberman MC, Kong WJ, Holt JR, Chen ZY, Liu DR.

Nature. 2018 Jan 11;553(7687):217-221. doi: 10.1038/nature25164. Epub 2017 Dec 20.


Wisp2 disruption represses Cxcr4 expression and inhibits BMSCs homing to injured liver.

Qin D, Yan Y, Hu B, Zhang W, Li H, Li X, Liu S, Dai D, Hu X, Huang X, Zhang L.

Oncotarget. 2017 Oct 24;8(58):98823-98836. doi: 10.18632/oncotarget.22006. eCollection 2017 Nov 17.


Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy.

Barkal AA, Weiskopf K, Kao KS, Gordon SR, Rosental B, Yiu YY, George BM, Markovic M, Ring NG, Tsai JM, McKenna KM, Ho PY, Cheng RZ, Chen JY, Barkal LJ, Ring AM, Weissman IL, Maute RL.

Nat Immunol. 2018 Jan;19(1):76-84. doi: 10.1038/s41590-017-0004-z. Epub 2017 Nov 27.


Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance.

Li Z, Chan K, Qi Y, Lu L, Ning F, Wu M, Wang H, Wang Y, Cai S, Du J.

Cancer Res Treat. 2018 Jul;50(3):894-907. doi: 10.4143/crt.2017.356. Epub 2017 Sep 18.


Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway.

Zhou L, Dong X, Wang L, Shan L, Li T, Xu W, Ding Y, Lai M, Lin X, Dai M, Bai X, Jia C, Zheng H.

Oncotarget. 2017 Apr 27;8(34):56267-56280. doi: 10.18632/oncotarget.17453. eCollection 2017 Aug 22.


Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring.

Yates CC, Rodrigues M, Nuschke A, Johnson ZI, Whaley D, Stolz D, Newsome J, Wells A.

Stem Cell Res Ther. 2017 Sep 5;8(1):193. doi: 10.1186/s13287-017-0644-9.


Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

Martínez-Sánchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buqué X, Aurrekoetxea I, Delgado TC, Vázquez-Martínez R, González-García I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Martínez de Morentin PB, López-González T, Liñares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-Gómez G, Davis RJ, Casals N, Orešič M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malagón MM, Diéguez C, Martínez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, López M.

Cell Metab. 2017 Jul 5;26(1):212-229.e12. doi: 10.1016/j.cmet.2017.06.014.


Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model.

Mohsen Z, Sim H, Garcia-Galiano D, Han X, Bellefontaine N, Saunders TL, Elias CF.

Brain Struct Funct. 2017 Dec;222(9):4111-4129. doi: 10.1007/s00429-017-1456-5. Epub 2017 Jun 14.


Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis.

Sridharan H, Ragan KB, Guo H, Gilley RP, Landsteiner VJ, Kaiser WJ, Upton JW.

EMBO Rep. 2017 Aug;18(8):1429-1441. doi: 10.15252/embr.201743947. Epub 2017 Jun 12.


Sequencing on the SOLiD 5500xl System - in-depth characterization of the GC bias.

Roeh S, Weber P, Rex-Haffner M, Deussing JM, Binder EB, Jakovcevski M.

Nucleus. 2017 Jul 4;8(4):370-380. doi: 10.1080/19491034.2017.1320461. Epub 2017 Apr 27.


Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteins.

Liu J, Li X, Zhang H, Gu R, Wang Z, Gao Z, Xing L.

Bone Joint Res. 2017 Mar;6(3):154-161. doi: 10.1302/2046-3758.63.BJR-2016-0237.R1.


Simplified qPCR method for detecting excessive mtDNA damage induced by exogenous factors.

Gureev AP, Shaforostova EA, Starkov AA, Popov VN.

Toxicology. 2017 May 1;382:67-74. doi: 10.1016/j.tox.2017.03.010. Epub 2017 Mar 9.


Ablation of RNA interference and retrotransposons accompany acquisition and evolution of transposases to heterochromatin protein CENPB.

Upadhyay U, Srivastava S, Khatri I, Nanda JS, Subramanian S, Arora A, Singh J.

Mol Biol Cell. 2017 Apr 15;28(8):1132-1146. doi: 10.1091/mbc.E16-07-0485. Epub 2017 Feb 22.


Astragalus polysaccharides attenuate PCV2 infection by inhibiting endoplasmic reticulum stress in vivo and in vitro.

Xue H, Gan F, Qian G, Hu J, Hao S, Xu J, Chen X, Huang K.

Sci Rep. 2017 Jan 10;7:40440. doi: 10.1038/srep40440.


Gi-DREADD Expression in Peripheral Nerves Produces Ligand-Dependent Analgesia, as well as Ligand-Independent Functional Changes in Sensory Neurons.

Saloman JL, Scheff NN, Snyder LM, Ross SE, Davis BM, Gold MS.

J Neurosci. 2016 Oct 19;36(42):10769-10781.


Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans.

Lossow K, Hübner S, Roudnitzky N, Slack JP, Pollastro F, Behrens M, Meyerhof W.

J Biol Chem. 2016 Jul 15;291(29):15358-77. doi: 10.1074/jbc.M116.718544. Epub 2016 May 20.


MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.

Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R.

Autophagy. 2015;11(7):1081-98. doi: 10.1080/15548627.2015.1040970.


Stimulation of Proliferation and Migration of Mouse Macrophages by Type B CpG-ODNs Is F-Spondin and IL-1Ra Dependent.

Chen TA, Liao CC, Cheng YC, Chen YP, Hsu YF, Liang CM, Liang SM.

PLoS One. 2015 Jun 4;10(6):e0128926. doi: 10.1371/journal.pone.0128926. eCollection 2015.

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