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Molecular cloning and characterization of a novel human STE20-like kinase, hSLK.

Yamada E, Tsujikawa K, Itoh S, Kameda Y, Kohama Y, Yamamoto H.

Biochim Biophys Acta. 2000 Feb 28;1495(3):250-62.


A yeast gene that is essential for release from glucose repression encodes a protein kinase.

Celenza JL, Carlson M.

Science. 1986 Sep 12;233(4769):1175-80.


SLK/LOSK kinase regulates cell motility independently of microtubule organization and Golgi polarization.

Fokin AI, Klementeva TS, Nadezhdina ES, Burakov AV.

Cytoskeleton (Hoboken). 2016 Feb;73(2):83-92. doi: 10.1002/cm.21276. Epub 2016 Feb 22.


SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation.

Machicoane M, de Frutos CA, Fink J, Rocancourt M, Lombardi Y, Garel S, Piel M, Echard A.

J Cell Biol. 2014 Jun 23;205(6):791-9. doi: 10.1083/jcb.201401049.


Regulation of the Ste20-like kinase, SLK: involvement of activation segment phosphorylation.

Luhovy AY, Jaberi A, Papillon J, Guillemette J, Cybulsky AV.

J Biol Chem. 2012 Feb 17;287(8):5446-58. doi: 10.1074/jbc.M111.302018. Epub 2011 Dec 27.


The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.

Roovers K, Wagner S, Storbeck CJ, O'Reilly P, Lo V, Northey JJ, Chmielecki J, Muller WJ, Siegel PM, Sabourin LA.

Oncogene. 2009 Aug 6;28(31):2839-48. doi: 10.1038/onc.2009.146. Epub 2009 Jun 15.


Ste20-related protein kinase LOSK (SLK) controls microtubule radial array in interphase.

Burakov AV, Zhapparova ON, Kovalenko OV, Zinovkina LA, Potekhina ES, Shanina NA, Weiss DG, Kuznetsov SA, Nadezhdina ES.

Mol Biol Cell. 2008 May;19(5):1952-61. doi: 10.1091/mbc.E06-12-1156. Epub 2008 Feb 20.


Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform.

Yan Y, Nguyen H, Dalmasso G, Sitaraman SV, Merlin D.

Biochim Biophys Acta. 2007 Feb;1769(2):106-16. Epub 2007 Jan 23.


Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome.

Zhapparova ON, Fokin AI, Vorobyeva NE, Bryantseva SA, Nadezhdina ES.

Mol Biol Cell. 2013 Oct;24(20):3205-14. doi: 10.1091/mbc.E13-03-0137. Epub 2013 Aug 28.


Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells.

Viswanatha R, Ohouo PY, Smolka MB, Bretscher A.

J Cell Biol. 2012 Dec 10;199(6):969-84. doi: 10.1083/jcb.201207047. Epub 2012 Dec 3.


v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II.

Chaar Z, O'reilly P, Gelman I, Sabourin LA.

J Biol Chem. 2006 Sep 22;281(38):28193-9. Epub 2006 Jul 12.


Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region.

Sabourin LA, Tamai K, Seale P, Wagner J, Rudnicki MA.

Mol Cell Biol. 2000 Jan;20(2):684-96. Erratum in: Mol Cell Biol 2000 Apr;20(8):2949.


Identification of Tpr and ╬▒-actinin-4 as two novel SLK-interacting proteins.

Jaberi A, Hooker E, Guillemette J, Papillon J, Kristof AS, Cybulsky AV.

Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2539-52. doi: 10.1016/j.bbamcr.2015.06.005. Epub 2015 Jun 18.


SLK-mediated phosphorylation of paxillin is required for focal adhesion turnover and cell migration.

Quizi JL, Baron K, Al-Zahrani KN, O'Reilly P, Sriram RK, Conway J, Laurin AA, Sabourin LA.

Oncogene. 2013 Sep 26;32(39):4656-63. doi: 10.1038/onc.2012.488. Epub 2012 Nov 5.


Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4.

Baron KD, Al-Zahrani K, Conway J, Labr├Ęche C, Storbeck CJ, Visvader JE, Sabourin LA.

Biochim Biophys Acta. 2015 Jul;1853(7):1683-92. doi: 10.1016/j.bbamcr.2015.04.003. Epub 2015 Apr 14. Erratum in: Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2754.


Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.

Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB.

Cancer Res. 2014 Feb 1;74(3):808-17. doi: 10.1158/0008-5472.CAN-13-1655. Epub 2013 Dec 9.


A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.

Cha PC, Takahashi A, Hosono N, Low SK, Kamatani N, Kubo M, Nakamura Y.

Nat Genet. 2011 May;43(5):447-50. doi: 10.1038/ng.805. Epub 2011 Apr 3.


Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.

Hast BE, Goldfarb D, Mulvaney KM, Hast MA, Siesser PF, Yan F, Hayes DN, Major MB.

Cancer Res. 2013 Apr 1;73(7):2199-210. doi: 10.1158/0008-5472.CAN-12-4400. Epub 2013 Feb 4.


Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.

Pike AC, Rellos P, Niesen FH, Turnbull A, Oliver AW, Parker SA, Turk BE, Pearl LH, Knapp S.

EMBO J. 2008 Feb 20;27(4):704-14. doi: 10.1038/emboj.2008.8. Epub 2008 Jan 31.


Serological detection of cutaneous T-cell lymphoma-associated antigens.

Eichmuller S, Usener D, Dummer R, Stein A, Thiel D, Schadendorf D.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):629-34. Epub 2001 Jan 9.

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