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Items: 1 to 20 of 70

1.

Infantile cerebral and cerebellar atrophy is associated with a mutation in the MED17 subunit of the transcription preinitiation mediator complex.

Kaufmann R, Straussberg R, Mandel H, Fattal-Valevski A, Ben-Zeev B, Naamati A, Shaag A, Zenvirt S, Konen O, Mimouni-Bloch A, Dobyns WB, Edvardson S, Pines O, Elpeleg O.

Am J Hum Genet. 2010 Nov 12;87(5):667-70. doi: 10.1016/j.ajhg.2010.09.016. Epub 2010 Oct 14.

2.

Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries.

Kikuchi Y, Umemura H, Nishitani S, Iida S, Fukasawa R, Hayashi H, Hirose Y, Tanaka A, Sugasawa K, Ohkuma Y.

Genes Cells. 2015 Mar;20(3):191-202. doi: 10.1111/gtc.12210. Epub 2014 Dec 7.

3.

Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor.

Kim GH, Oh GS, Yoon J, Lee GG, Lee KU, Kim SW.

J Clin Invest. 2015 Jan;125(1):183-93. doi: 10.1172/JCI73615. Epub 2014 Dec 1.

4.

Mediator and post-recruitment regulation of RNA polymerase II.

Knuesel MT, Taatjes DJ.

Transcription. 2011 Jan-Feb;2(1):28-31. doi: 10.4161/trns.2.1.13950.

5.

Role of metazoan mediator proteins in interferon-responsive transcription.

Lau JF, Nusinzon I, Burakov D, Freedman LP, Horvath CM.

Mol Cell Biol. 2003 Jan;23(2):620-8.

6.

The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme.

Chiba N, Parvin JD.

Cancer Res. 2002 Aug 1;62(15):4222-8.

7.

Mediator CDK subunits are platforms for interactions with various chromatin regulatory complexes.

Fukasawa R, Tsutsui T, Hirose Y, Tanaka A, Ohkuma Y.

J Biochem. 2012 Sep;152(3):241-9. doi: 10.1093/jb/mvs065. Epub 2012 Jun 4.

PMID:
22668559
8.

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.

Stumpf M, Waskow C, Krötschel M, van Essen D, Rodriguez P, Zhang X, Guyot B, Roeder RG, Borggrefe T.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18504-9. Epub 2006 Nov 28. Erratum in: Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1442.

9.

Redistribution of BRCA1 among four different protein complexes following replication blockage.

Chiba N, Parvin JD.

J Biol Chem. 2001 Oct 19;276(42):38549-54. Epub 2001 Aug 14.

10.

Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.

Tsutsui T, Fukasawa R, Shinmyouzu K, Nakagawa R, Tobe K, Tanaka A, Ohkuma Y.

J Biol Chem. 2013 Jul 19;288(29):20955-65. doi: 10.1074/jbc.M113.486746. Epub 2013 Jun 9.

11.

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

Wallberg AE, Yamamura S, Malik S, Spiegelman BM, Roeder RG.

Mol Cell. 2003 Nov;12(5):1137-49.

12.
13.

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

Fondell JD, Ge H, Roeder RG.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8329-33.

14.

CDK8 is a positive regulator of transcriptional elongation within the serum response network.

Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM.

Nat Struct Mol Biol. 2010 Feb;17(2):194-201. doi: 10.1038/nsmb.1752. Epub 2010 Jan 24.

15.

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.

Mittler G, Stühler T, Santolin L, Uhlmann T, Kremmer E, Lottspeich F, Berti L, Meisterernst M.

EMBO J. 2003 Dec 15;22(24):6494-504.

16.

Structure, function, and activator-induced conformations of the CRSP coactivator.

Taatjes DJ, Näär AM, Andel F 3rd, Nogales E, Tjian R.

Science. 2002 Feb 8;295(5557):1058-62.

17.

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.

Meyer KD, Donner AJ, Knuesel MT, York AG, Espinosa JM, Taatjes DJ.

EMBO J. 2008 May 21;27(10):1447-57. doi: 10.1038/emboj.2008.78. Epub 2008 Apr 17.

18.

A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.

Sato S, Tomomori-Sato C, Banks CA, Parmely TJ, Sorokina I, Brower CS, Conaway RC, Conaway JW.

J Biol Chem. 2003 Dec 12;278(50):49671-4. Epub 2003 Oct 22.

19.

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

Ryu S, Zhou S, Ladurner AG, Tjian R.

Nature. 1999 Feb 4;397(6718):446-50.

PMID:
9989412
20.

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Näär AM, Erdjument-Bromage H, Tempst P, Freedman LP.

Nature. 1999 Apr 29;398(6730):824-8.

PMID:
10235266

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