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F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT.

Sun C, Tao Y, Gao Y, Xia Y, Liu Y, Wang G, Gu Y.

Biomed Pharmacother. 2018 Feb;98:416-423. doi: 10.1016/j.biopha.2017.12.088. Epub 2017 Dec 27.


Crystal structure of the UBR-box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding.

Muñoz-Escobar J, Kozlov G, Gehring K.

Protein Sci. 2017 Oct;26(10):2092-2097. doi: 10.1002/pro.3227. Epub 2017 Jul 25.


FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children.

Rye MS, Wiertsema SP, Scaman ES, Oommen J, Sun W, Francis RW, Ang W, Pennell CE, Burgner D, Richmond P, Vijayasekaran S, Coates HL, Brown SD, Blackwell JM, Jamieson SE.

Genes Immun. 2011 Jul;12(5):352-9. doi: 10.1038/gene.2011.2. Epub 2011 Feb 3.


[Expression of InnVit/FBXO11 in vitiligo and its role in tyrosinase export from endoplasmic reticulum].

Guan CP, Lin FQ, Hong WS, Fu LF, Zhou MN, Xu W, Xu AE.

Zhonghua Yi Xue Za Zhi. 2010 Apr 27;90(16):1126-30. Chinese.


The role of VIT1/FBXO11 in the regulation of apoptosis and tyrosinase export from endoplasmic reticulum in cultured melanocytes.

Guan C, Lin F, Zhou M, Hong W, Fu L, Xu W, Liu D, Wan Y, Xu A.

Int J Mol Med. 2010 Jul;26(1):57-65.


VIT1 gene and vitiligo.

Eapen BR.

Indian J Dermatol Venereol Leprol. 2004 May-Jun;70(3):184-5. No abstract available.


Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study.

Segade F, Daly KA, Allred D, Hicks PJ, Cox M, Brown M, Hardisty-Hughes RE, Brown SD, Rich SS, Bowden DW.

Arch Otolaryngol Head Neck Surg. 2006 Jul;132(7):729-33.


'VIT1', a novel gene associated with vitiligo.

Le Poole IC, Sarangarajan R, Zhao Y, Stennett LS, Brown TL, Sheth P, Miki T, Boissy RE.

Pigment Cell Res. 2001 Dec;14(6):475-84.


The tumor suppressive miR-26a regulation of FBXO11 inhibits proliferation, migration and invasion of hepatocellular carcinoma cells.

Ma Y, Deng F, Li P, Chen G, Tao Y, Wang H.

Biomed Pharmacother. 2018 May;101:648-655. doi: 10.1016/j.biopha.2018.02.118. Epub 2018 Mar 22.


The oncogenic microRNA-21 inhibits the tumor suppressive activity of FBXO11 to promote tumorigenesis.

Yang CH, Pfeffer SR, Sims M, Yue J, Wang Y, Linga VG, Paulus E, Davidoff AM, Pfeffer LM.

J Biol Chem. 2015 Mar 6;290(10):6037-46. doi: 10.1074/jbc.M114.632125. Epub 2015 Jan 14.


VIT1/FBXO11 knockdown induces morphological alterations and apoptosis in B10BR mouse melanocytes.

Li Y, Chen F, Lin F, Guan C, Wei X, Wan Y, Xu A.

Int J Mol Med. 2009 May;23(5):673-8.


FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.

Cook JR, Lee JH, Yang ZH, Krause CD, Herth N, Hoffmann R, Pestka S.

Biochem Biophys Res Commun. 2006 Apr 7;342(2):472-81. Epub 2006 Feb 8.


FBXO11 represses cellular response to hypoxia by destabilizing hypoxia-inducible factor-1α mRNA.

Ju UI, Park JW, Park HS, Kim SJ, Chun YS.

Biochem Biophys Res Commun. 2015 Sep 4;464(4):1008-1015. doi: 10.1016/j.bbrc.2015.07.037. Epub 2015 Jul 14.


MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity.

Xue J, Chi Y, Chen Y, Huang S, Ye X, Niu J, Wang W, Pfeffer LM, Shao ZM, Wu ZH, Wu J.

Oncogene. 2016 Jan 28;35(4):448-58. doi: 10.1038/onc.2015.96. Epub 2015 Apr 13.


CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.

Abbas T, Mueller AC, Shibata E, Keaton M, Rossi M, Dutta A.

Mol Cell. 2013 Mar 28;49(6):1147-58. doi: 10.1016/j.molcel.2013.02.003. Epub 2013 Mar 7.


Cardiac Nav 1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6.

Zhao C, Wang L, Ma X, Zhu W, Yao L, Cui Y, Liu Y, Li J, Liang X, Sun Y, Li L, Chen YH.

J Cell Mol Med. 2015 Sep;19(9):2143-52. doi: 10.1111/jcmm.12588. Epub 2015 Jun 7.


PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis.

Zheng H, Shen M, Zha YL, Li W, Wei Y, Blanco MA, Ren G, Zhou T, Storz P, Wang HY, Kang Y.

Cancer Cell. 2014 Sep 8;26(3):358-373. doi: 10.1016/j.ccr.2014.07.022.


HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins.

Hard RL, Liu J, Shen J, Zhou P, Pei D.

Biochemistry. 2010 Dec 21;49(50):10737-46. doi: 10.1021/bi101014s. Epub 2010 Nov 29.


FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity.

Abida WM, Nikolaev A, Zhao W, Zhang W, Gu W.

J Biol Chem. 2007 Jan 19;282(3):1797-804. Epub 2006 Nov 9.

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