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Items: 1 to 20 of 1345


Influence of c-Src on hypoxic resistance to paclitaxel in human ovarian cancer cells and reversal of FV-429.

Guo Q, Lu L, Liao Y, Wang X, Zhang Y, Liu Y, Huang S, Sun H, Li Z, Zhao L.

Cell Death Dis. 2018 Jan 11;8(1):e3178. doi: 10.1038/cddis.2017.367.


Src family kinases (SFKs) and cell polarity in the testis.

Xiao X, Ni Y, Yu C, Li L, Mao B, Yang Y, Zheng D, Silvestrini B, Cheng CY.

Semin Cell Dev Biol. 2018 Sep;81:46-53. doi: 10.1016/j.semcdb.2017.11.024. Epub 2017 Dec 6. Review.


Differentially activated Src kinase in chemo-naïve human primary osteosarcoma cells and effects of a Src kinase inhibitor.

Laschi M, Bernardini G, Geminiani M, Manetti F, Mori M, Spreafico A, Campanacci D, Capanna R, Schenone S, Botta M, Santucci A.

Biofactors. 2017 Nov;43(6):801-811. doi: 10.1002/biof.1382. Epub 2017 Aug 8.


Deregulation of c-Src tyrosine kinase and its downstream targets in pre-eclamptic placenta.

Irtegun S, Akcora-Yıldız D, Pektanc G, Karabulut C.

J Obstet Gynaecol Res. 2017 Aug;43(8):1278-1284. doi: 10.1111/jog.13350. Epub 2017 May 19.


A novel c-Src recruitment pathway from the cytosol to focal adhesions.

Machiyama H, Yamaguchi T, Watanabe TM, Fujita H.

FEBS Lett. 2017 Jul;591(13):1940-1946. doi: 10.1002/1873-3468.12696. Epub 2017 Jun 10.


Activation of Src tyrosine kinase in esophageal carcinoma cells in different regulatory environments and corresponding occurrence mechanism.

Yu ZS, Song XH, Gan HM, Geng DZ, Yang J.

Genet Mol Res. 2016 Aug 26;15(3). doi: 10.4238/gmr.15038026.


c-Src activation promotes nasopharyngeal carcinoma metastasis by inducing the epithelial-mesenchymal transition via PI3K/Akt signaling pathway: a new and promising target for NPC.

Ke L, Xiang Y, Guo X, Lu J, Xia W, Yu Y, Peng Y, Wang L, Wang G, Ye Y, Yang J, Liang H, Kang T, Lv X.

Oncotarget. 2016 May 10;7(19):28340-55. doi: 10.18632/oncotarget.8634.


c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry.

McCarthy SD, Sakac D, Neschadim A, Branch DR.

AIDS. 2016 Mar 27;30(6):849-58. doi: 10.1097/QAD.0000000000001028.


Subcellular and Dynamic Coordination between Src Activity and Cell Protrusion in Microenvironment.

Zhuo Y, Qian T, Wu Y, Seong J, Gong Y, Ma H, Wang Y, Lu S.

Sci Rep. 2015 Aug 11;5:12963. doi: 10.1038/srep12963.


SH3 domain of c-Src governs its dynamics at focal adhesions and the cell membrane.

Machiyama H, Yamaguchi T, Sawada Y, Watanabe TM, Fujita H.

FEBS J. 2015 Oct;282(20):4034-55. doi: 10.1111/febs.13404. Epub 2015 Sep 11.


The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets.

Wu Y, Span LM, Nygren P, Zhu H, Moore DT, Cheng H, Roder H, DeGrado WF, Bennett JS.

J Biol Chem. 2015 Jun 19;290(25):15825-34. doi: 10.1074/jbc.M115.648428. Epub 2015 May 6.


The SH3 Domain Acts as a Scaffold for the N-Terminal Intrinsically Disordered Regions of c-Src.

Maffei M, Arbesú M, Le Roux AL, Amata I, Roche S, Pons M.

Structure. 2015 May 5;23(5):893-902. doi: 10.1016/j.str.2015.03.009. Epub 2015 Apr 23.


Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.

Liu YN, Yin J, Barrett B, Sheppard-Tillman H, Li D, Casey OM, Fang L, Hynes PG, Ameri AH, Kelly K.

Mol Cell Biol. 2015 Jun 1;35(11):1940-51. doi: 10.1128/MCB.00008-15. Epub 2015 Mar 23.


The prognostic significance of Src and p-Src expression in patients with osteosarcoma.

Hu C, Deng Z, Zhang Y, Yan L, Cai L, Lei J, Xie Y.

Med Sci Monit. 2015 Feb 28;21:638-45. doi: 10.12659/MSM.892803.


Radiation promotes malignant phenotypes through SRC in breast cancer cells.

Kim RK, Cui YH, Yoo KC, Kim IG, Lee M, Choi YH, Suh Y, Lee SJ.

Cancer Sci. 2015 Jan;106(1):78-85. doi: 10.1111/cas.12574. Epub 2014 Dec 23.


The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.

Young JC, Clements A, Lang AE, Garnett JA, Munera D, Arbeloa A, Pearson J, Hartland EL, Matthews SJ, Mousnier A, Barry DJ, Way M, Schlosser A, Aktories K, Frankel G.

Nat Commun. 2014 Dec 19;5:5887. doi: 10.1038/ncomms6887.


c-Src binds to the cancer drug Ruxolitinib with an active conformation.

Duan Y, Chen L, Chen Y, Fan XG.

PLoS One. 2014 Sep 8;9(9):e106225. doi: 10.1371/journal.pone.0106225. eCollection 2014.


Antitumor activity of miR-1280 in melanoma by regulation of Src.

Sun V, Zhou WB, Nosrati M, Majid S, Thummala S, de Semir D, Bezrookove V, de Feraudy S, Chun L, Schadendorf D, Debs R, Kashani-Sabet M, Dar AA.

Mol Ther. 2015 Jan;23(1):71-8. doi: 10.1038/mt.2014.176. Epub 2014 Sep 8.


Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow.

Wan Q, Xu W, Yan JL, Yokota H, Na S.

PLoS One. 2014 Aug 26;9(8):e105699. doi: 10.1371/journal.pone.0105699. eCollection 2014.


Computational approaches for evaluating the effect of sequence variations and the intrinsically disordered C-terminal region of the Helicobacter pylori CagA protein on the interaction with tyrosine kinase Src.

Delgado P, Peñaranda N, Zamora MA, del Pilar Delgado M, Bohorquez E, Castro H, Barrios AF, Jaramillo C.

J Mol Model. 2014 Aug;20(8):2406. doi: 10.1007/s00894-014-2406-2. Epub 2014 Aug 14.


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