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Items: 1 to 20 of 42

1.

The Integrator complex controls the termination of transcription at diverse classes of gene targets.

Skaar JR, Ferris AL, Wu X, Saraf A, Khanna KK, Florens L, Washburn MP, Hughes SH, Pagano M.

Cell Res. 2015 Mar;25(3):288-305. doi: 10.1038/cr.2015.19. Epub 2015 Feb 13.

2.

Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding.

Vidhyasagar V, He Y, Guo M, Talwar T, Singh RS, Yadav M, Katselis G, Vizeacoumar FJ, Lukong KE, Wu Y.

Biochem J. 2018 Jan 2;475(1):45-60. doi: 10.1042/BCJ20170351.

3.

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.

Kar A, Kaur M, Ghosh T, Khan MM, Sharma A, Shekhar R, Varshney A, Saxena S.

Nucleic Acids Res. 2015 May 26;43(10):4962-74. doi: 10.1093/nar/gkv369. Epub 2015 Apr 27.

4.

Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response.

Yang S, Quaresma AJ, Nickerson JA, Green KM, Shaffer SA, Imbalzano AN, Martin-Buley LA, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Sci. 2015 Feb 15;128(4):728-40. doi: 10.1242/jcs.160051. Epub 2015 Jan 20.

5.

Integrator3, a partner of single-stranded DNA-binding protein 1, participates in the DNA damage response.

Zhang F, Wu J, Yu X.

J Biol Chem. 2009 Oct 30;284(44):30408-15. doi: 10.1074/jbc.M109.039404. Epub 2009 Sep 15.

6.

A core hSSB1-INTS complex participates in the DNA damage response.

Zhang F, Ma T, Yu X.

J Cell Sci. 2013 Nov 1;126(Pt 21):4850-5. doi: 10.1242/jcs.132514. Epub 2013 Aug 28.

7.

INTS3 controls the hSSB1-mediated DNA damage response.

Skaar JR, Richard DJ, Saraf A, Toschi A, Bolderson E, Florens L, Washburn MP, Khanna KK, Pagano M.

J Cell Biol. 2009 Oct 5;187(1):25-32. doi: 10.1083/jcb.200907026. Epub 2009 Sep 28.

8.

CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma.

Inagaki Y, Yasui K, Endo M, Nakajima T, Zen K, Tsuji K, Minami M, Tanaka S, Taniwaki M, Itoh Y, Arii S, Okanoue T.

Cancer Genet Cytogenet. 2008 Jan 1;180(1):30-6.

PMID:
18068530
9.

Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres.

Gu P, Deng W, Lei M, Chang S.

Cell Res. 2013 May;23(5):705-19. doi: 10.1038/cr.2013.31. Epub 2013 Mar 5.

10.

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

Li Y, Bolderson E, Kumar R, Muniandy PA, Xue Y, Richard DJ, Seidman M, Pandita TK, Khanna KK, Wang W.

J Biol Chem. 2009 Aug 28;284(35):23525-31. doi: 10.1074/jbc.C109.039586. Epub 2009 Jul 14.

11.

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK.

Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883. Epub 2008 Apr 30.

PMID:
18449195
12.

SOSS complexes participate in the maintenance of genomic stability.

Huang J, Gong Z, Ghosal G, Chen J.

Mol Cell. 2009 Aug 14;35(3):384-93. doi: 10.1016/j.molcel.2009.06.011.

13.

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.

Cotta-Ramusino C, McDonald ER 3rd, Hurov K, Sowa ME, Harper JW, Elledge SJ.

Science. 2011 Jun 10;332(6035):1313-7. doi: 10.1126/science.1203430.

14.

Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.

Jodoin JN, Sitaram P, Albrecht TR, May SB, Shboul M, Lee E, Reversade B, Wagner EJ, Lee LA.

Mol Biol Cell. 2013 Sep;24(18):2954-65. doi: 10.1091/mbc.E13-05-0254. Epub 2013 Jul 31.

15.

Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.

Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F.

Genome Res. 2001 Aug;11(8):1392-403.

16.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes.

Malovannaya A, Li Y, Bulynko Y, Jung SY, Wang Y, Lanz RB, O'Malley BW, Qin J.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2431-6. doi: 10.1073/pnas.0912599106. Epub 2010 Jan 22. Erratum in: Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6118.

17.

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R.

Cell. 2005 Oct 21;123(2):265-76.

18.

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

Cox JL, Wilder PJ, Gilmore JM, Wuebben EL, Washburn MP, Rizzino A.

PLoS One. 2013 May 7;8(5):e62857. doi: 10.1371/journal.pone.0062857. Print 2013.

19.

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

Maréchal A, Li JM, Ji XY, Wu CS, Yazinski SA, Nguyen HD, Liu S, Jiménez AE, Jin J, Zou L.

Mol Cell. 2014 Jan 23;53(2):235-246. doi: 10.1016/j.molcel.2013.11.002. Epub 2013 Dec 12.

20.

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B.

Mol Cell. 2007 Jul 20;27(2):262-74.

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