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Association of BAX hypermethylation with coronary heart disease is specific to individuals aged over 70.

Zhang L, Ji H, Huang Y, Hu H, Li B, Yang Y, Yu H, Chen X, Li W, Liu F, Wang S, Wang C, Chen K, Bao Y, Liu H, Duan S.

Medicine (Baltimore). 2019 Jan;98(4):e14130. doi: 10.1097/MD.0000000000014130.


Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy.

Wang PG, Li YT, Pan Y, Gao ZZ, Guan XW, Jia L, Liu FT.

J Neurooncol. 2019 Jan;141(1):71-81. doi: 10.1007/s11060-018-03031-9. Epub 2018 Nov 16.


Expression of Bax/Bcl-2, TGF-β1, and Type III Collagen Fiber in Congenital Muscular Torticollis.

Li D, Wang K, Zhang W, Wang J.

Med Sci Monit. 2018 Nov 3;24:7869-7874. doi: 10.12659/MSM.909064.


Prognostic value and susceptibility of BAX rs4645878 polymorphism in cancer: A systematic review and meta-analysis.

Feng Y, Chen X, Zheng Y, Liu Q, Chen H, Cai Y, Cao L, Lai X, Pan L, Li Y, Wang SY.

Medicine (Baltimore). 2018 Jul;97(29):e11591. doi: 10.1097/MD.0000000000011591. Review.


Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.

Kale J, Kutuk O, Brito GC, Andrews TS, Leber B, Letai A, Andrews DW.

EMBO Rep. 2018 Sep;19(9). pii: e45235. doi: 10.15252/embr.201745235. Epub 2018 Jul 9.


The role of cardiolipin in promoting the membrane pore-forming activity of BAX oligomers.

Lai YC, Li CC, Sung TC, Chang CW, Lan YJ, Chiang YW.

Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):268-280. doi: 10.1016/j.bbamem.2018.06.014. Epub 2018 Jun 26.


Changes in platelet Bax levels contribute to impaired platelet response to thrombin after cardiopulmonary bypass: prospective observational clinical and laboratory investigations.

Murase M, Nakayama Y, Sessler DI, Mukai N, Ogawa S, Nakajima Y.

Br J Anaesth. 2017 Dec 1;119(6):1118-1126. doi: 10.1093/bja/aex349.


The pro-apoptotic BAX protein influences cell growth and differentiation from the nucleus in healthy interphasic cells.

Brayer S, Joannes A, Jaillet M, Gregianin E, Mahmoudi S, Marchal Sommé J, Fabre A, Mordant P, Cazes A, Crestani B, Mailleux AA.

Cell Cycle. 2017;16(21):2108-2118. doi: 10.1080/15384101.2017.1371882. Epub 2017 Sep 21.


Apoptotic Bax at Oxidatively Stressed Mitochondrial Membranes: Lipid Dynamics and Permeabilization.

Dingeldein APG, Pokorná Š, Lidman M, Sparrman T, Šachl R, Hof M, Gröbner G.

Biophys J. 2017 May 23;112(10):2147-2158. doi: 10.1016/j.bpj.2017.04.019.


Effect of photodynamic therapy based on indocyanine green on expression of apoptosis-related genes in human gingival fibroblast cells.

Gharesi S, Pourhajibagher M, Chiniforush N, Raoofian R, Hashemi M, Shahabi S, Bahador A.

Photodiagnosis Photodyn Ther. 2017 Sep;19:33-36. doi: 10.1016/j.pdpdt.2017.04.007. Epub 2017 Apr 21.


Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML.

Reichenbach F, Wiedenmann C, Schalk E, Becker D, Funk K, Scholz-Kreisel P, Todt F, Wolleschak D, Döhner K, Marquardt JU, Heidel F, Edlich F.

Clin Cancer Res. 2017 Aug 15;23(16):4805-4816. doi: 10.1158/1078-0432.CCR-16-1941. Epub 2017 Apr 18.


Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells.

Daniele S, Pietrobono D, Costa B, Giustiniano M, La Pietra V, Giacomelli C, La Regina G, Silvestri R, Taliani S, Trincavelli ML, Da Settimo F, Novellino E, Martini C, Marinelli L.

ACS Chem Neurosci. 2018 Jan 17;9(1):85-99. doi: 10.1021/acschemneuro.7b00023. Epub 2017 Apr 11.


The substitution of Proline 168 favors Bax oligomerization and stimulates its interaction with LUVs and mitochondria.

Simonyan L, Légiot A, Lascu I, Durand G, Giraud MF, Gonzalez C, Manon S.

Biochim Biophys Acta Biomembr. 2017 Jun;1859(6):1144-1155. doi: 10.1016/j.bbamem.2017.03.010. Epub 2017 Mar 16.


Ginsenoside Rg3 promotes cytotoxicity of Paclitaxel through inhibiting NF-κB signaling and regulating Bax/Bcl-2 expression on triple-negative breast cancer.

Yuan Z, Jiang H, Zhu X, Liu X, Li J.

Biomed Pharmacother. 2017 May;89:227-232. doi: 10.1016/j.biopha.2017.02.038. Epub 2017 Feb 20.


Enterovirus 71 induces apoptosis by directly modulating the conformational activation of pro-apoptotic protein Bax.

Han X, Cong H.

J Gen Virol. 2017 Mar;98(3):422-434. doi: 10.1099/jgv.0.000705. Epub 2017 Apr 1.


The BAX gene as a candidate for negative autophagy-related genes regulator on mRNA levels in colorectal cancer.

Gil J, Ramsey D, Szmida E, Leszczynski P, Pawlowski P, Bebenek M, Sasiadek MM.

Med Oncol. 2017 Feb;34(2):16. doi: 10.1007/s12032-016-0869-y. Epub 2016 Dec 29.


Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane.

Zhang M, Zheng J, Nussinov R, Ma B.

Sci Rep. 2016 Sep 15;6:33340. doi: 10.1038/srep33340.


Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation.

Liao C, Zhang Z, Kale J, Andrews DW, Lin J, Li J.

Sci Rep. 2016 Jul 6;6:29502. doi: 10.1038/srep29502.


High BAX/BCL2 mRNA ratio predicts favorable prognosis in laryngeal squamous cell carcinoma, particularly in patients with negative lymph nodes at the time of diagnosis.

Giotakis AI, Kontos CK, Manolopoulos LD, Sismanis A, Konstadoulakis MM, Scorilas A.

Clin Biochem. 2016 Aug;49(12):890-6. doi: 10.1016/j.clinbiochem.2016.04.010. Epub 2016 Apr 26.


The Octyl Ester of Ginsenoside Rh2 Induces Lysosomal Membrane Permeabilization via Bax Translocation.

Chen F, Zhang B, Sun Y, Xiong ZX, Peng H, Deng ZY, Hu JN.

Nutrients. 2016 Apr 25;8(5). pii: E244. doi: 10.3390/nu8050244.

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