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Items: 1 to 20 of 53

1.

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.

Thomsen SK, Raimondo A, Hastoy B, Sengupta S, Dai XQ, Bautista A, Censin J, Payne AJ, Umapathysivam MM, Spigelman AF, Barrett A, Groves CJ, Beer NL, Manning Fox JE, McCarthy MI, Clark A, Mahajan A, Rorsman P, MacDonald PE, Gloyn AL.

Nat Genet. 2018 Aug;50(8):1122-1131. doi: 10.1038/s41588-018-0173-1. Epub 2018 Jul 27.

2.

The peptidylglycine-α-amidating monooxygenase (PAM) gene rs13175330 A>G polymorphism is associated with hypertension in a Korean population.

Yoo HJ, Kim M, Kim M, Chae JS, Lee SH, Lee JH.

Hum Genomics. 2017 Nov 21;11(1):29. doi: 10.1186/s40246-017-0125-3.

3.

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.

Bäck N, Kanerva K, Kurutihalli V, Yanik A, Ikonen E, Mains RE, Eipper BA.

Eur J Cell Biol. 2017 Aug;96(5):407-417. doi: 10.1016/j.ejcb.2017.03.007. Epub 2017 Mar 28.

4.

Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase.

Chauhan S, Hosseinzadeh P, Lu Y, Blackburn NJ.

Biochemistry. 2016 Apr 5;55(13):2008-21. doi: 10.1021/acs.biochem.6b00061. Epub 2016 Mar 23.

5.

Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli.

Handa S, Spradling TJ, Dempsey DR, Merkler DJ.

Protein Expr Purif. 2012 Jul;84(1):9-13. doi: 10.1016/j.pep.2012.04.012. Epub 2012 Apr 25.

6.

A copper-methionine interaction controls the pH-dependent activation of peptidylglycine monooxygenase.

Bauman AT, Broers BA, Kline CD, Blackburn NJ.

Biochemistry. 2011 Dec 20;50(50):10819-28. doi: 10.1021/bi201193j. Epub 2011 Nov 22.

7.

The peptidylglycine alpha-amidating monooxygenase (PAM): a novel prodrug strategy for amidoximes and N-hydroxyguanidines?

Schade D, Kotthaus J, Hungeling H, Kotthaus J, Clement B.

ChemMedChem. 2009 Oct;4(10):1595-9. doi: 10.1002/cmdc.200900233. No abstract available.

PMID:
19693765
8.

Immunocytochemical finding of the amidating enzymes in mouse pancreatic A-, B-, and D-cells: a comparison with human and rat.

Garmendia O, Rodríguez MP, Burrell MA, Villaro AC.

J Histochem Cytochem. 2002 Oct;50(10):1401-16.

PMID:
12364573
9.

Peptidylglycine alpha-amidating monooxygenase- and proadrenomedullin-derived peptide-associated neuroendocrine differentiation are induced by androgen deprivation in the neoplastic prostate.

Jiménez N, Jongsma J, Calvo A, van der Kwast TH, Treston AM, Cuttitta F, Schröder FH, Montuenga LM, van Steenbrugge GJ.

Int J Cancer. 2001 Oct 1;94(1):28-34.

10.

Peptide-amidating enzymes are expressed in the stellate epithelial cells of the thymic medulla.

Martínez A, Farr A, Vos MD, Cuttitta F, Treston AM.

J Histochem Cytochem. 1998 May;46(5):661-8.

PMID:
9562574
11.

Distribution of peptidyl-glycine alpha-amidating mono-oxygenase (PAM) enzymes in normal human lung and in lung epithelial tumors.

Saldise L, Martínez A, Montuenga LM, Treston A, Springall DR, Polak JM, Vázquez JJ.

J Histochem Cytochem. 1996 Jan;44(1):3-12.

12.

Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains.

Eipper BA, Milgram SL, Husten EJ, Yun HY, Mains RE.

Protein Sci. 1993 Apr;2(4):489-97. Review.

13.
14.

Localization of the gene encoding peptidylglycine alpha-amidating monooxygenase (PAM) to human chromosome 5q14-5q21.

Ouafik LH, Mattei MG, Giraud P, Oliver C, Eipper BA, Mains RE.

Genomics. 1993 Nov;18(2):319-21.

PMID:
8288234
15.
16.

Peptide alpha-amidation activity in human plasma: relationship to gastrin processing.

Kapuscinski M, Green M, Sinha SN, Shepherd JJ, Shulkes A.

Clin Endocrinol (Oxf). 1993 Jul;39(1):51-8.

PMID:
8102327
17.

Immunocytochemical localization of peptidylglycine alpha-amidating monooxygenase enzymes (PAM) in human endocrine pancreas.

Martínez A, Montuenga LM, Springall DR, Treston A, Cuttitta F, Polak JM.

J Histochem Cytochem. 1993 Mar;41(3):375-80.

18.

Isolation and functional expression of human pancreatic peptidylglycine alpha-amidating monooxygenase.

Tateishi K, Arakawa F, Misumi Y, Treston AM, Vos M, Matsuoka Y.

Biochem Biophys Res Commun. 1994 Nov 30;205(1):282-90. Erratum in: Biochem Biophys Res Commun 1995 Jan 17;206(2):805.

PMID:
7999037
19.

The NH2-terminal proregion of peptidylglycine alpha-amidating monooxygenase facilitates the secretion of soluble proteins.

Mains RE, Milgram SL, Keutmann HT, Eipper BA.

Mol Endocrinol. 1995 Jan;9(1):3-13.

PMID:
7760848
20.

Increased peptidylglycine alpha-amidating monooxygenase activity in cerebrospinal fluid of patients with multiple sclerosis.

Tsukamoto T, Noguchi M, Kayama H, Watanabe T, Asoh T, Yamamoto T.

Intern Med. 1995 Apr;34(4):229-32.

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