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MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions.

Keogh N, Chan KY, Li GM, Lahue RS.

Nucleic Acids Res. 2017 Sep 29;45(17):10068-10078. doi: 10.1093/nar/gkx650.


Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma.

Ni H, Jiang B, Zhou Z, Yuan X, Cao X, Huang G, Li Y.

Int J Mol Med. 2017 Sep;40(3):673-678. doi: 10.3892/ijmm.2017.3044. Epub 2017 Jun 27.


Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.

Moss DJH, Pardiñas AF, Langbehn D, Lo K, Leavitt BR, Roos R, Durr A, Mead S; TRACK-HD investigators; REGISTRY investigators, Holmans P, Jones L, Tabrizi SJ.

Lancet Neurol. 2017 Sep;16(9):701-711. doi: 10.1016/S1474-4422(17)30161-8. Epub 2017 Jun 20. Erratum in: Lancet Neurol. 2017 Sep;16(9):683.


Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6.

Morak M, Käsbauer S, Kerscher M, Laner A, Nissen AM, Benet-Pagès A, Schackert HK, Keller G, Massdorf T, Holinski-Feder E.

Fam Cancer. 2017 Oct;16(4):491-500. doi: 10.1007/s10689-017-9975-z.


Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.

Adam R, Spier I, Zhao B, Kloth M, Marquez J, Hinrichsen I, Kirfel J, Tafazzoli A, Horpaopan S, Uhlhaas S, Stienen D, Friedrichs N, Altmüller J, Laner A, Holzapfel S, Peters S, Kayser K, Thiele H, Holinski-Feder E, Marra G, Kristiansen G, Nöthen MM, Büttner R, Möslein G, Betz RC, Brieger A, Lifton RP, Aretz S.

Am J Hum Genet. 2016 Aug 4;99(2):337-51. doi: 10.1016/j.ajhg.2016.06.015. Epub 2016 Jul 28.


A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients.

Morales F, Vásquez M, Santamaría C, Cuenca P, Corrales E, Monckton DG.

DNA Repair (Amst). 2016 Apr;40:57-66. doi: 10.1016/j.dnarep.2016.01.001. Epub 2016 Mar 8.


MSH3 rs26279 polymorphism increases cancer risk: a meta-analysis.

Miao HK, Chen LP, Cai DP, Kong WJ, Xiao L, Lin J.

Int J Clin Exp Pathol. 2015 Sep 1;8(9):11060-7. eCollection 2015.


Correlation of MSH3 polymorphisms with response and survival in advanced non-small cell lung cancer patients treated with first-line platinum-based chemotherapy.

Xu XL, Yao YL, Xu WZ, Feng JG, Mao WM.

Genet Mol Res. 2015 Apr 15;14(2):3525-33. doi: 10.4238/2015.April.15.16.


Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke.

Vogelsang M, Paccez JD, Schäfer G, Dzobo K, Zerbini LF, Parker MI.

J Cancer Res Clin Oncol. 2014 Nov;140(11):1825-33. doi: 10.1007/s00432-014-1736-x. Epub 2014 Jun 17.


MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.

Park JM, Huang S, Tougeron D, Sinicrope FA.

PLoS One. 2013 May 28;8(5):e65369. doi: 10.1371/journal.pone.0065369. Print 2013.


Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells.

Tseng-Rogenski SS, Chung H, Wilk MB, Zhang S, Iwaizumi M, Carethers JM.

PLoS One. 2012;7(11):e50616. doi: 10.1371/journal.pone.0050616. Epub 2012 Nov 30.


Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer.

Li J, Koike J, Kugoh H, Arita M, Ohhira T, Kikuchi Y, Funahashi K, Takamatsu K, Boland CR, Koi M, Hemmi H.

Biochim Biophys Acta. 2012 Apr;1823(4):889-99. doi: 10.1016/j.bbamcr.2012.01.017. Epub 2012 Feb 9.


Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability.

Plaschke J, Preußler M, Ziegler A, Schackert HK.

Int J Colorectal Dis. 2012 Jul;27(7):911-9. doi: 10.1007/s00384-011-1408-0. Epub 2012 Jan 10.


MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor.

Takahashi M, Koi M, Balaguer F, Boland CR, Goel A.

J Biol Chem. 2011 Apr 8;286(14):12157-65. doi: 10.1074/jbc.M110.198804. Epub 2011 Feb 1.


Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias.

Lee SY, Chung H, Devaraj B, Iwaizumi M, Han HS, Hwang DY, Seong MK, Jung BH, Carethers JM.

Gastroenterology. 2010 Nov;139(5):1519-25. doi: 10.1053/j.gastro.2010.08.001. Epub 2010 Aug 11.


DNA mismatch repair enzyme immunohistochemistry in colorectal cancer: a comparison of biopsy and resection material.

Kumarasinghe AP, de Boer B, Bateman AC, Kumarasinghe MP.

Pathology. 2010;42(5):414-20. doi: 10.3109/00313025.2010.493862.


Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.

Haugen AC, Goel A, Yamada K, Marra G, Nguyen TP, Nagasaka T, Kanazawa S, Koike J, Kikuchi Y, Zhong X, Arita M, Shibuya K, Oshimura M, Hemmi H, Boland CR, Koi M.

Cancer Res. 2008 Oct 15;68(20):8465-72. doi: 10.1158/0008-5472.CAN-08-0002.


Inactivation of the hMSH3 mismatch repair gene in bladder cancer.

Kawakami T, Shiina H, Igawa M, Deguchi M, Nakajima K, Ogishima T, Tokizane T, Urakami S, Enokida H, Miura K, Ishii N, Kane CJ, Carroll PR, Dahiya R.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):934-42.


DNA mismatch repair and mutation avoidance pathways.

Marti TM, Kunz C, Fleck O.

J Cell Physiol. 2002 Apr;191(1):28-41. Review.


Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability.

Orimo H, Nakajima E, Yamamoto M, Ikejima M, Emi M, Shimada T.

J Hum Genet. 2000;45(4):228-30.


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