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Items: 1 to 20 of 922

1.

Promoter methylation of human mutL homolog 1 and colorectal cancer risk: A meta-analysis.

Shi B, Chu J, Gao Q, Tian T.

J Cancer Res Ther. 2018;14(4):851-855. doi: 10.4103/0973-1482.172587.

2.

Identification of a mutL‑homolog 1 mutation via whole‑exome sequencing in a Chinese family with Gardner syndrome.

Lv Z, Wang C, Wu L, Guo B, Zhang D, Zhang Y, Huang S, Ou M.

Mol Med Rep. 2018 Jul;18(1):987-992. doi: 10.3892/mmr.2018.9063. Epub 2018 May 23.

PMID:
29845239
3.

Uterine endometrial carcinoma with DNA mismatch repair deficiency: magnetic resonance imaging findings and clinical features.

Minamiguchi K, Takahama J, Uchiyama T, Taiji R, Saito N, Okada H, Marugami N, Tanase Y, Kawaguchi R, Ohbayashi C, Kobayashi H, Hirai T, Kichikawa K.

Jpn J Radiol. 2018 Jul;36(7):429-436. doi: 10.1007/s11604-018-0741-4. Epub 2018 May 4.

PMID:
29728922
4.

The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences.

Jia P, Chai W.

DNA Repair (Amst). 2018 May;65:20-25. doi: 10.1016/j.dnarep.2018.03.002. Epub 2018 Mar 7.

PMID:
29544212
5.

Evaluation of MLH1 variants of unclear significance.

Köger N, Paulsen L, López-Kostner F, Della Valle A, Vaccaro CA, Palmero EI, Alvarez K, Sarroca C, Neffa F, Kalfayan PG, Gonzalez ML, Rossi BM, Reis RM, Brieger A, Zeuzem S, Hinrichsen I, Dominguez-Valentin M, Plotz G.

Genes Chromosomes Cancer. 2018 Jul;57(7):350-358. doi: 10.1002/gcc.22536. Epub 2018 Apr 30.

PMID:
29520894
6.

Aberrant methylation of mutL homolog 1 is associated with increased risk of non-small cell lung cancer.

Hu H, Chen X, Zhou C, Li B, Yang Y, Ying X, Mao Y, Zhang Y, Zhong J, Dai J, Yu H, Wu B, Li X, Wang T, Duan S.

J Clin Lab Anal. 2018 Jun;32(5):e22370. doi: 10.1002/jcla.22370. Epub 2017 Dec 5.

PMID:
29205508
7.

Association between promoter methylation of MLH1 and MSH2 and reactive oxygen species in oligozoospermic men-A pilot study.

Gunes S, Agarwal A, Henkel R, Mahmutoglu AM, Sharma R, Esteves SC, Aljowair A, Emirzeoglu D, Alkhani A, Pelegrini L, Joumah A, Sabanegh E.

Andrologia. 2018 Apr;50(3). doi: 10.1111/and.12903. Epub 2017 Oct 6.

PMID:
28983945
8.

A modifier of Huntington's disease onset at the MLH1 locus.

Lee JM, Chao MJ, Harold D, Abu Elneel K, Gillis T, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF.

Hum Mol Genet. 2017 Oct 1;26(19):3859-3867. doi: 10.1093/hmg/ddx286.

PMID:
28934397
9.

Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival.

Cosgrove CM, Cohn DE, Hampel H, Frankel WL, Jones D, McElroy JP, Suarez AA, Zhao W, Chen W, Salani R, Copeland LJ, O'Malley DM, Fowler JM, Yilmaz A, Chassen AS, Pearlman R, Goodfellow PJ, Backes FJ.

Gynecol Oncol. 2017 Sep;146(3):588-595. doi: 10.1016/j.ygyno.2017.07.003. Epub 2017 Jul 11.

10.
11.

Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer.

Meunier K, Ferron M, Calmel C, Fléjou JF, Pocard M, Praz F.

Genes Chromosomes Cancer. 2017 Sep;56(9):681-690. doi: 10.1002/gcc.22472. Epub 2017 Jun 12.

PMID:
28512763
12.

Effect of histone modifications on hMLH1 alternative splicing in gastric cancer.

Zhao JX, Li XW, Shi BY, Wang F, Xu ZR, Meng HL, Su YY, Wang JM, Xiao N, He Q, Wang YP, Fan YM.

Tumour Biol. 2017 Apr;39(4):1010428317697546. doi: 10.1177/1010428317697546.

PMID:
28381181
13.

The silent mutation MLH1 c.543C>T resulting in aberrant splicing can cause Lynch syndrome: a case report.

Yamaguchi T, Wakatsuki T, Kikuchi M, Horiguchi SI, Akagi K.

Jpn J Clin Oncol. 2017 Jun 1;47(6):576-580. doi: 10.1093/jjco/hyx023.

PMID:
28334867
14.

Modulation of transcription factor binding and epigenetic regulation of the MLH1 CpG island and shore by polymorphism rs1800734 in colorectal cancer.

Savio AJ, Bapat B.

Epigenetics. 2017 Jun 3;12(6):441-448. doi: 10.1080/15592294.2017.1305527. Epub 2017 Mar 17.

15.

The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer.

Savio AJ, Mrkonjic M, Lemire M, Gallinger S, Knight JA, Bapat B.

Clin Epigenetics. 2017 Mar 9;9:26. doi: 10.1186/s13148-017-0326-6. eCollection 2017.

16.

Expression and promoter DNA methylation of MLH1 in colorectal cancer and lung cancer.

Ma Y, Chen Y, Petersen I.

Pathol Res Pract. 2017 Apr;213(4):333-338. doi: 10.1016/j.prp.2017.01.014. Epub 2017 Jan 22.

PMID:
28214209
17.

Human MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.

Jia P, Chastain M, Zou Y, Her C, Chai W.

Nucleic Acids Res. 2017 Feb 17;45(3):1219-1232. doi: 10.1093/nar/gkw1170.

18.

Autophagy influences the low-dose hyper-radiosensitivity of human lung adenocarcinoma cells by regulating MLH1.

Wang Q, Xiao Z, Lin Z, Zhou J, Chen W, Jie W, Cao X, Yin Z, Cheng J.

Int J Radiat Biol. 2017 Jun;93(6):600-606. doi: 10.1080/09553002.2017.1286052. Epub 2017 Feb 13.

PMID:
28117625
19.

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients.

Fu T, Liu Y, Li K, Wan W, Pappou EP, Iacobuzio-Donahue CA, Kerner Z, Baylin SB, Wolfgang CL, Ahuja N.

Oncotarget. 2016 Dec 27;7(52):86480-86489. doi: 10.18632/oncotarget.13441.

20.

Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency.

Xia M, Singhi AD, Dudley B, Brand R, Nikiforova M, Pai RK.

Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):399-406. doi: 10.1097/PAI.0000000000000389.

PMID:
27258561

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