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Items: 1 to 20 of 340

1.

Dysregulation of astrocyte extracellular signaling in Costello syndrome.

Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM.

Sci Transl Med. 2015 May 6;7(286):286ra66. doi: 10.1126/scitranslmed.aaa5645.

2.

An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.

Salotti J, Sakchaisri K, Tourtellotte WG, Johnson PF.

Mol Cell Biol. 2015 Mar;35(5):866-83. doi: 10.1128/MCB.01489-14. Epub 2014 Dec 22.

3.

Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.

Chen X, Makarewicz JM, Knauf JA, Johnson LK, Fagin JA.

Oncogene. 2014 Nov 20;33(47):5442-9. doi: 10.1038/onc.2013.489. Epub 2013 Nov 18.

4.

The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts.

Thevathasan JV, Tan E, Zheng H, Lin YC, Li Y, Inoue T, Fivaz M.

Mol Biol Cell. 2013 Jul;24(14):2228-37. doi: 10.1091/mbc.E12-12-0905. Epub 2013 May 15.

5.

The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors.

Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D.

J Neurosci. 2012 Nov 7;32(45):15849-58. doi: 10.1523/JNEUROSCI.2846-12.2012.

6.

H-Ras isoform modulates extracellular matrix synthesis, proliferation, and migration in fibroblasts.

Fuentes-Calvo I, Blázquez-Medela AM, Eleno N, Santos E, López-Novoa JM, Martínez-Salgado C.

Am J Physiol Cell Physiol. 2012 Feb 15;302(4):C686-97. doi: 10.1152/ajpcell.00103.2011. Epub 2011 Nov 16.

7.

Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex.

Kaneko M, Cheetham CE, Lee YS, Silva AJ, Stryker MP, Fox K.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19026-31. doi: 10.1073/pnas.1013866107. Epub 2010 Oct 11.

8.

Neuronal Ras activation inhibits adult hippocampal progenitor cell division and impairs spatial short-term memory.

Manns M, Bichler Z, Leske O, Heumann R.

Genes Brain Behav. 2010 Jul;9(5):525-36. doi: 10.1111/j.1601-183X.2010.00584.x. Epub 2010 Apr 6.

9.

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice.

Grande MT, Fuentes-Calvo I, Arévalo M, Heredia F, Santos E, Martínez-Salgado C, Rodríguez-Puyol D, Nieto MA, López-Novoa JM.

Kidney Int. 2010 Mar;77(6):509-18. doi: 10.1038/ki.2009.498. Epub 2009 Dec 23.

10.

Constitutively enhanced p21Ras activity amplifies dendritic remodeling of hippocampal neurons during physical activity.

Alpár A, Naumann N, Arendt T, Gärtner U.

Int J Dev Neurosci. 2009 Jun;27(4):407-11. doi: 10.1016/j.ijdevneu.2009.03.002. Epub 2009 Mar 13.

PMID:
19460636
11.

Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.

Chen X, Mitsutake N, LaPerle K, Akeno N, Zanzonico P, Longo VA, Mitsutake S, Kimura ET, Geiger H, Santos E, Wendel HG, Franco A, Knauf JA, Fagin JA.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):7979-84. doi: 10.1073/pnas.0900343106. Epub 2009 Apr 29.

12.

Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation.

Grande MT, Arévalo M, Núñez A, Cannata-Andía JB, Santos E, López-Novoa JM.

World J Urol. 2009 Dec;27(6):787-97. doi: 10.1007/s00345-009-0399-8.

PMID:
19288266
13.

Regulation and function of neuronal GTP-Ras in facial motor nerve regeneration.

Makwana M, Serchov T, Hristova M, Bohatschek M, Gschwendtner A, Kalla R, Liu Z, Heumann R, Raivich G.

J Neurochem. 2009 Mar;108(6):1453-63. doi: 10.1111/j.1471-4159.2009.05890.x.

14.

Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes.

Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A.

Am J Pathol. 2008 Dec;173(6):1861-72. doi: 10.2353/ajpath.2008.080376. Epub 2008 Nov 6.

15.

Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway.

Strong JE, Wong G, Jones SE, Grolla A, Theriault S, Kobinger GP, Feldmann H.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17982-7. doi: 10.1073/pnas.0809698105. Epub 2008 Nov 3.

16.

Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome.

Viosca J, Schuhmacher AJ, Guerra C, Barco A.

Genes Brain Behav. 2009 Feb;8(1):60-71. doi: 10.1111/j.1601-183X.2008.00443.x. Epub 2008 Sep 22.

17.

Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations.

Ren YX, Finckenstein FG, Abdueva DA, Shahbazian V, Chung B, Weinberg KI, Triche TJ, Shimada H, Anderson MJ.

Cancer Res. 2008 Aug 15;68(16):6587-97. doi: 10.1158/0008-5472.CAN-08-0859.

18.

Enhanced Ras activity preserves dendritic size and extension as well as synaptic contacts of neurons after functional deprivation in synRas mice.

Alpár A, Naumann N, Härtig W, Arendt T, Gärtner U.

Eur J Neurosci. 2008 Jun;27(12):3083-94. doi: 10.1111/j.1460-9568.2008.06313.x.

PMID:
18598255
19.

Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos.

Lu CW, Yabuuchi A, Chen L, Viswanathan S, Kim K, Daley GQ.

Nat Genet. 2008 Jul;40(7):921-6. doi: 10.1038/ng.173. Epub 2008 Jun 8.

20.

H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors.

Serban D, Leng J, Cheresh D.

Circ Res. 2008 Jun 6;102(11):1350-8. doi: 10.1161/CIRCRESAHA.107.169664. Epub 2008 May 8.

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