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Items: 1 to 20 of 26


Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.

Lu D, Choi MY, Yu J, Castro JE, Kipps TJ, Carson DA.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7. doi: 10.1073/pnas.1110431108. Epub 2011 Jul 25.


Plasma PLTP (phospholipid-transfer protein): an emerging role in 'reverse lipopolysaccharide transport' and innate immunity.

Gautier T, Lagrost L.

Biochem Soc Trans. 2011 Aug;39(4):984-8. doi: 10.1042/BST0390984.


The role of S100 genes in breast cancer progression.

McKiernan E, McDermott EW, Evoy D, Crown J, Duffy MJ.

Tumour Biol. 2011 Jun;32(3):441-50. doi: 10.1007/s13277-010-0137-2. Epub 2010 Dec 14.


Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D.

Clin Cancer Res. 2010 May 1;16(9):2580-90. doi: 10.1158/1078-0432.CCR-09-2937. Epub 2010 Apr 13.


CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts.

Ginestier C, Liu S, Diebel ME, Korkaya H, Luo M, Brown M, Wicinski J, Cabaud O, Charafe-Jauffret E, Birnbaum D, Guan JL, Dontu G, Wicha MS.

J Clin Invest. 2010 Feb;120(2):485-97. doi: 10.1172/JCI39397. Epub 2010 Jan 4.


Nuclear protein 1 induced by ATF4 in response to various stressors acts as a positive regulator on the transcriptional activation of ATF4.

Jin HO, Seo SK, Woo SH, Choe TB, Hong SI, Kim JI, Park IC.

IUBMB Life. 2009 Dec;61(12):1153-8. doi: 10.1002/iub.271.


Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.

Kakarala M, Brenner DE, Korkaya H, Cheng C, Tazi K, Ginestier C, Liu S, Dontu G, Wicha MS.

Breast Cancer Res Treat. 2010 Aug;122(3):777-85. doi: 10.1007/s10549-009-0612-x. Epub 2009 Nov 7.


Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.

Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K.

Cancer Res. 2009 Oct 1;69(19):7507-11. doi: 10.1158/0008-5472.CAN-09-2994. Epub 2009 Sep 14. Erratum in: Cancer Res. 2009 Nov 15;69(22):8832.


Identification of selective inhibitors of cancer stem cells by high-throughput screening.

Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES.

Cell. 2009 Aug 21;138(4):645-659. doi: 10.1016/j.cell.2009.06.034. Epub 2009 Aug 13.


Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer.

Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung MC, Hortobagyi GN, Gonzalez-Angulo AM.

J Clin Oncol. 2009 Jul 10;27(20):3297-302. doi: 10.1200/JCO.2009.19.6410. Epub 2009 Jun 1.


Association of reactive oxygen species levels and radioresistance in cancer stem cells.

Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF.

Nature. 2009 Apr 9;458(7239):780-3. doi: 10.1038/nature07733.


Berberine diminishes the side population and ABCG2 transporter expression in MCF-7 breast cancer cells.

Kim JB, Ko E, Han W, Shin I, Park SY, Noh DY.

Planta Med. 2008 Nov;74(14):1693-700. doi: 10.1055/s-0028-1088313. Epub 2008 Oct 24.


Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis.

Eyler CE, Rich JN.

J Clin Oncol. 2008 Jun 10;26(17):2839-45. doi: 10.1200/JCO.2007.15.1829. Review.


Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model.

Zhou J, Zhang H, Gu P, Margolick JB, Yin D, Zhang Y.

Breast Cancer Res Treat. 2009 May;115(2):269-77. doi: 10.1007/s10549-008-0072-8. Epub 2008 May 28.


The epithelial-mesenchymal transition generates cells with properties of stem cells.

Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA.

Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027.


Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.

Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA.

Cancer Res. 2008 May 15;68(10):3645-54. doi: 10.1158/0008-5472.CAN-07-2938.


Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy.

Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC.

J Natl Cancer Inst. 2008 May 7;100(9):672-9. doi: 10.1093/jnci/djn123. Epub 2008 Apr 29.


NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.

Zhou J, Zhang H, Gu P, Bai J, Margolick JB, Zhang Y.

Breast Cancer Res Treat. 2008 Oct;111(3):419-27. Epub 2007 Oct 27.


Cancer stem cells and radiotherapy: new insights into tumor radioresistance.

Diehn M, Clarke MF.

J Natl Cancer Inst. 2006 Dec 20;98(24):1755-7. No abstract available.


Structure-function of alpha1-adrenergic receptors.

Perez DM.

Biochem Pharmacol. 2007 Apr 15;73(8):1051-62. Epub 2006 Sep 16. Review.

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