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Items: 9


Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.

Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP.

Stem Cell Res. 2011 Mar;6(2):92-102. doi: 10.1016/j.scr.2010.12.002. Epub 2010 Dec 10.


Persistence of functional hepatocyte-like cells in immune-compromised mice.

Payne CM, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine CN, Forbes SJ, Iredale JP, Newsome PN, Hay DC.

Liver Int. 2011 Feb;31(2):254-62. doi: 10.1111/j.1478-3231.2010.02414.x. Epub 2010 Dec 10.


The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation.

Hannoun Z, Fletcher J, Greenhough S, Medine C, Samuel K, Sharma R, Pryde A, Black JR, Ross JA, Wilmut I, Iredale JP, Hay DC.

Cell Reprogram. 2010 Apr;12(2):133-40. doi: 10.1089/cell.2009.0099.


Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.

Greenhough S, Medine CN, Hay DC.

Toxicology. 2010 Dec 30;278(3):250-5. doi: 10.1016/j.tox.2010.07.012. Epub 2010 Jul 30. Review.


Role of stem-cell-derived hepatic endoderm in human drug discovery.

Medine CN, Greenhough S, Hay DC.

Biochem Soc Trans. 2010 Aug;38(4):1033-6. doi: 10.1042/BST0381033. Review.


Induced pluripotent stem cells: a new era for hepatology.

Asgari S, Pournasr B, Salekdeh GH, Ghodsizadeh A, Ott M, Baharvand H.

J Hepatol. 2010 Oct;53(4):738-51. doi: 10.1016/j.jhep.2010.05.009. Epub 2010 Jun 22. Review.


Progress and future challenges in stem cell-derived liver technologies.

Dalgetty DM, Medine CN, Iredale JP, Hay DC.

Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G241-8. doi: 10.1152/ajpgi.00138.2009. Epub 2009 Jun 11. Review. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G619.


Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.

Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RC, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z, Pryde A, Filippi C, Currie IS, Forbes SJ, Ross JA, Newsome PN, Iredale JP.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12301-6. doi: 10.1073/pnas.0806522105. Epub 2008 Aug 21.


The inhibitory role of stromal cell mesenchyme on human embryonic stem cell hepatocyte differentiation is overcome by Wnt3a treatment.

Fletcher J, Cui W, Samuel K, Black JR, Hannoun Z, Currie IS, Terrace JD, Payne C, Filippi C, Newsome P, Forbes SJ, Ross JA, Iredale JP, Hay DC.

Cloning Stem Cells. 2008 Sep;10(3):331-9. doi: 10.1089/clo.2007.0094.


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