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Items: 1 to 20 of 27

1.

Acute Lymphoblastic Leukemia in Children.

Hunger SP, Mullighan CG.

N Engl J Med. 2015 Oct 15;373(16):1541-52. doi: 10.1056/NEJMra1400972. Review. No abstract available.

PMID:
26465987
2.

TPMT Polymorphism: When Shield Becomes Weakness.

Katara P, Kuntal H.

Interdiscip Sci. 2016 Jun;8(2):150-5. doi: 10.1007/s12539-015-0111-1. Review.

PMID:
26297310
3.

Should thiopurine methyltransferase (TPMT) activity be determined before prescribing azathioprine, mercaptopurine, or thioguanine?

DiPiero J, Teng K, Hicks JK.

Cleve Clin J Med. 2015 Jul;82(7):409-13. doi: 10.3949/ccjm.82a.14106. No abstract available.

4.

Optimizing the use of thiopurines in inflammatory bowel disease.

Goel RM, Blaker P, Mentzer A, Fong SC, Marinaki AM, Sanderson JD.

Ther Adv Chronic Dis. 2015 May;6(3):138-46. doi: 10.1177/2040622315579063. Review.

5.

Association between thiopurine S-methyltransferase polymorphisms and thiopurine-induced adverse drug reactions in patients with inflammatory bowel disease: a meta-analysis.

Liu YP, Wu HY, Yang X, Xu HQ, Li YC, Shi DC, Huang JF, Huang Q, Fu WL.

PLoS One. 2015 Mar 23;10(3):e0121745. doi: 10.1371/journal.pone.0121745.

6.
7.

Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis.

Kotlyar DS, Lewis JD, Beaugerie L, Tierney A, Brensinger CM, Gisbert JP, Loftus EV Jr, Peyrin-Biroulet L, Blonski WC, Van Domselaar M, Chaparro M, Sandilya S, Bewtra M, Beigel F, Biancone L, Lichtenstein GR.

Clin Gastroenterol Hepatol. 2015 May;13(5):847-58.e4; quiz e48-50. doi: 10.1016/j.cgh.2014.05.015.

PMID:
24879926
8.

Identification of a novel thiopurine S-methyltransferase allele (TPMT*37).

Roberts RL, Wallace MC, Drake JM, Stamp LK.

Pharmacogenet Genomics. 2014 Jun;24(6):320-3. doi: 10.1097/FPC.0000000000000049.

PMID:
24710034
9.

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.

Matimba A, Li F, Livshits A, Cartwright CS, Scully S, Fridley BL, Jenkins G, Batzler A, Wang L, Weinshilboum R, Lennard L.

Pharmacogenomics. 2014 Mar;15(4):433-47. doi: 10.2217/pgs.13.226.

10.

Thiopurine monitoring in children with inflammatory bowel disease: a systematic review.

Konidari A, Anagnostopoulos A, Bonnett LJ, Pirmohamed M, El-Matary W.

Br J Clin Pharmacol. 2014 Sep;78(3):467-76. doi: 10.1111/bcp.12365. Review.

11.

Risk of lymphoma in patients with ulcerative colitis treated with thiopurines: a nationwide retrospective cohort study.

Khan N, Abbas AM, Lichtenstein GR, Loftus EV Jr, Bazzano LA.

Gastroenterology. 2013 Nov;145(5):1007-1015.e3. doi: 10.1053/j.gastro.2013.07.035.

PMID:
23891975
12.

Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Hicks JK, Schwab M, Klein TE; Clinical Pharmacogenetics Implementation Consortium..

Clin Pharmacol Ther. 2013 Apr;93(4):324-5. doi: 10.1038/clpt.2013.4. No abstract available.

13.

Nomenclature for alleles of the thiopurine methyltransferase gene.

Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA.

Pharmacogenet Genomics. 2013 Apr;23(4):242-8. doi: 10.1097/FPC.0b013e32835f1cc0.

14.

Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.

Lennard L, Cartwright CS, Wade R, Richards SM, Vora A.

Br J Clin Pharmacol. 2013 Jul;76(1):125-36. doi: 10.1111/bcp.12066.

15.

Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function.

Hindorf U, Appell ML.

J Crohns Colitis. 2012 Jul;6(6):655-9. doi: 10.1016/j.crohns.2011.11.014.

PMID:
22398041
16.

Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol.

Smith MA, Blaker P, Marinaki AM, Anderson SH, Irving PM, Sanderson JD.

J Crohns Colitis. 2012 Oct;6(9):905-12. doi: 10.1016/j.crohns.2012.02.007.

PMID:
22386736
17.

Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients.

González-Lama Y, Bermejo F, López-Sanromán A, García-Sánchez V, Esteve M, Cabriada JL, McNicholl AG, Pajares R, Casellas F, Merino O, Carpio D, Vera MI, Muñoz C, Calvo M, Benito LM, Bujanda L, García-Fernández FJ, Ricart E, Ginard D, Velasco M, Carneros JA, Manceñido N, Calvo M, Algaba A, Froilan C, Cara C, Maté J, Abreu L, Gisbert JP; "Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU)"..

Aliment Pharmacol Ther. 2011 Sep;34(5):544-54. doi: 10.1111/j.1365-2036.2011.04756.x.

18.

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Klein TE; Clinical Pharmacogenetics Implementation Consortium..

Clin Pharmacol Ther. 2011 Mar;89(3):387-91. doi: 10.1038/clpt.2010.320. Erratum in: Clin Pharmacol Ther. 2011 Dec;90(6):894.

19.

Novel thiopurine methyltransferase variant TPMT*28 results in a misdiagnosis of TPMT deficiency.

Landy J, Bhuva N, Marinaki A, Mawdsley J.

Inflamm Bowel Dis. 2011 Jun;17(6):1441-2. doi: 10.1002/ibd.21505. No abstract available.

PMID:
20945351
20.

Very important pharmacogene summary: thiopurine S-methyltransferase.

Wang L, Pelleymounter L, Weinshilboum R, Johnson JA, Hebert JM, Altman RB, Klein TE.

Pharmacogenet Genomics. 2010 Jun;20(6):401-5. doi: 10.1097/FPC.0b013e3283352860. Review. No abstract available.

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