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Items: 1 to 20 of 29

1.

A novel technology for the imaging of acidic prostate tumors by positron emission tomography.

Vāvere AL, Biddlecombe GB, Spees WM, Garbow JR, Wijesinghe D, Andreev OA, Engelman DM, Reshetnyak YK, Lewis JS.

Cancer Res. 2009 May 15;69(10):4510-6. doi: 10.1158/0008-5472.CAN-08-3781. Epub 2009 May 5.

2.

Microenvironmental regulation of metastasis.

Joyce JA, Pollard JW.

Nat Rev Cancer. 2009 Apr;9(4):239-52. doi: 10.1038/nrc2618. Epub 2008 Mar 12. Review.

3.

The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion.

Silva AS, Yunes JA, Gillies RJ, Gatenby RA.

Cancer Res. 2009 Mar 15;69(6):2677-84. doi: 10.1158/0008-5472.CAN-08-2394. Epub 2009 Mar 10.

4.

Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane.

Reshetnyak YK, Andreev OA, Segala M, Markin VS, Engelman DM.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15340-5. doi: 10.1073/pnas.0804746105. Epub 2008 Sep 30.

5.

Dissecting the membrane binding and insertion kinetics of a pHLIP peptide.

Tang J, Gai F.

Biochemistry. 2008 Aug 12;47(32):8250-2. doi: 10.1021/bi801103x. Epub 2008 Jul 18.

PMID:
18636715
6.

The tumor microenvironment and metastatic disease.

Lunt SJ, Chaudary N, Hill RP.

Clin Exp Metastasis. 2009;26(1):19-34. doi: 10.1007/s10585-008-9182-2. Epub 2008 Jun 10. Review.

PMID:
18543068
7.

Molecular and functional MRI of the tumor microenvironment.

Penet MF, Glunde K, Jacobs MA, Pathak AP, Bhujwalla ZM.

J Nucl Med. 2008 May;49(5):687-90. doi: 10.2967/jnumed.107.043349. Epub 2008 Apr 15. Review. No abstract available.

8.

Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumors.

Zoonens M, Reshetnyak YK, Engelman DM.

Biophys J. 2008 Jul;95(1):225-35. doi: 10.1529/biophysj.107.124156. Epub 2008 Mar 21.

9.

A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers.

Reshetnyak YK, Segala M, Andreev OA, Engelman DM.

Biophys J. 2007 Oct 1;93(7):2363-72. Epub 2007 Jun 8.

10.

Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo.

Andreev OA, Dupuy AD, Segala M, Sandugu S, Serra DA, Chichester CO, Engelman DM, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7893-8. Epub 2007 May 1.

11.

Regulation of tumor pH and the role of carbonic anhydrase 9.

Swietach P, Vaughan-Jones RD, Harris AL.

Cancer Metastasis Rev. 2007 Jun;26(2):299-310. Review.

PMID:
17415526
12.

Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize.

Fukumura D, Jain RK.

J Cell Biochem. 2007 Jul 1;101(4):937-49. Review.

PMID:
17171643
13.

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.

Rofstad EK, Mathiesen B, Kindem K, Galappathi K.

Cancer Res. 2006 Jul 1;66(13):6699-707.

14.

Acid-mediated tumor invasion: a multidisciplinary study.

Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ.

Cancer Res. 2006 May 15;66(10):5216-23.

15.

Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.

Reshetnyak YK, Andreev OA, Lehnert U, Engelman DM.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6460-5. Epub 2006 Apr 11.

16.

Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment.

Cairns R, Papandreou I, Denko N.

Mol Cancer Res. 2006 Feb;4(2):61-70. Review.

17.

Fluorescent peptide probes for in vivo diagnostic imaging.

Tung CH.

Biopolymers. 2004;76(5):391-403.

PMID:
15389488
18.

Lighting up tumors with receptor-specific optical molecular probes.

Achilefu S.

Technol Cancer Res Treat. 2004 Aug;3(4):393-409. Review.

PMID:
15270591
19.

Tumor microenvironmental physiology and its implications for radiation oncology.

Vaupel P.

Semin Radiat Oncol. 2004 Jul;14(3):198-206. Review.

PMID:
15254862
20.

Molecular and functional imaging of cancer: advances in MRI and MRS.

Pathak AP, Gimi B, Glunde K, Ackerstaff E, Artemov D, Bhujwalla ZM.

Methods Enzymol. 2004;386:3-60. No abstract available.

PMID:
15120245

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