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Items: 1 to 20 of 126

1.

Rational design of dual-functional aptamers that inhibit the protease and helicase activities of HCV NS3.

Umehara T, Fukuda K, Nishikawa F, Kohara M, Hasegawa T, Nishikawa S.

J Biochem. 2005 Mar;137(3):339-47.

PMID:
15809335
2.

A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase.

Levin MK, Gurjar M, Patel SS.

Nat Struct Mol Biol. 2005 May;12(5):429-35. Epub 2005 Apr 3.

PMID:
15806107
3.

Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro.

Tackett AJ, Chen Y, Cameron CE, Raney KD.

J Biol Chem. 2005 Mar 18;280(11):10797-806. Epub 2005 Jan 4.

4.

An RNA ligand inhibits hepatitis C virus NS3 protease and helicase activities.

Fukuda K, Umehara T, Sekiya S, Kunio K, Hasegawa T, Nishikawa S.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):670-5.

PMID:
15541341
5.

Hepatitis C NS3 helicase unwinds RNA in leaps and bounds.

Bianco PR.

Lancet. 2004 Oct 16-22;364(9443):1385-7. No abstract available.

PMID:
15488202
6.

Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations.

Frick DN, Rypma RS, Lam AM, Frenz CM.

Nucleic Acids Res. 2004 Oct 12;32(18):5519-28. Print 2004.

7.

Inhibition of hepatitis C virus nonstructural protein, helicase activity, and viral replication by a recombinant human antibody clone.

Prabhu R, Khalap N, Burioni R, Clementi M, Garry RF, Dash S.

Am J Pathol. 2004 Oct;165(4):1163-73.

8.

Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.

Gai D, Zhao R, Li D, Finkielstein CV, Chen XS.

Cell. 2004 Oct 1;119(1):47-60.

9.

Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases.

James JA, Aggarwal AK, Linden RM, Escalante CR.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12455-60. Epub 2004 Aug 13.

10.

In vitro selection of RNA aptamers against the HCV NS3 helicase domain.

Nishikawa F, Funaji K, Fukuda K, Nishikawa S.

Oligonucleotides. 2004;14(2):114-29.

PMID:
15294075
11.

Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding.

Lam AM, Rypma RS, Frick DN.

Nucleic Acids Res. 2004 Aug 2;32(13):4060-70. Print 2004.

12.

Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase.

Serebrov V, Pyle AM.

Nature. 2004 Jul 22;430(6998):476-80.

PMID:
15269774
13.

Helicase primase: targeting the Achilles heel of herpes simplex viruses.

Kleymann G.

Antivir Chem Chemother. 2004 May;15(3):135-40. Review.

PMID:
15266895
14.

Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus.

Hwang B, Cho JS, Yeo HJ, Kim JH, Chung KM, Han K, Jang SK, Lee SW.

RNA. 2004 Aug;10(8):1277-90. Epub 2004 Jul 9.

15.

WebLogo: a sequence logo generator.

Crooks GE, Hon G, Chandonia JM, Brenner SE.

Genome Res. 2004 Jun;14(6):1188-90.

16.

The functional interaction of the hepatitis C virus helicase molecules is responsible for unwinding processivity.

Levin MK, Wang YH, Patel SS.

J Biol Chem. 2004 Jun 18;279(25):26005-12. Epub 2004 Apr 14.

17.

Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.

Bretner M, Schalinski S, Haag A, Lang M, Schmitz H, Baier A, Behrens SE, Kulikowski T, Borowski P.

Antivir Chem Chemother. 2004 Jan;15(1):35-42.

PMID:
15074713
18.

The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling.

Crampton DJ, Guo S, Johnson DE, Richardson CC.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4373-8.

19.

Hepatitis C virus NS3 RNA helicase activity is modulated by the two domains of NS3 and NS4A.

Kuang WF, Lin YC, Jean F, Huang YW, Tai CL, Chen DS, Chen PJ, Hwang LH.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):211-7.

PMID:
15047170
20.

Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.

Liu D, Windsor WT, Wyss DF.

Protein Sci. 2003 Dec;12(12):2757-67.

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