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Items: 1 to 20 of 41

1.

Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.

Fricker FR, Zhu N, Tsantoulas C, Abrahamsen B, Nassar MA, Thakur M, Garratt AN, Birchmeier C, McMahon SB, Wood JN, Bennett DL.

J Neurosci. 2009 Jun 17;29(24):7667-78. doi: 10.1523/JNEUROSCI.6053-08.2009.

2.

Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

Narayanan SP, Flores AI, Wang F, Macklin WB.

J Neurosci. 2009 May 27;29(21):6860-70. doi: 10.1523/JNEUROSCI.0232-09.2009.

3.

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation.

Kao SC, Wu H, Xie J, Chang CP, Ranish JA, Graef IA, Crabtree GR.

Science. 2009 Jan 30;323(5914):651-4. doi: 10.1126/science.1166562.

4.

ErbB3 is required for ductal morphogenesis in the mouse mammary gland.

Jackson-Fisher AJ, Bellinger G, Breindel JL, Tavassoli FA, Booth CJ, Duong JK, Stern DF.

Breast Cancer Res. 2008;10(6):R96. doi: 10.1186/bcr2198. Epub 2008 Nov 18.

5.

Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation.

Monje PV, Athauda G, Wood PM.

J Biol Chem. 2008 Dec 5;283(49):34087-100. doi: 10.1074/jbc.M802318200. Epub 2008 Sep 17.

6.

Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.

Brinkmann BG, Agarwal A, Sereda MW, Garratt AN, Müller T, Wende H, Stassart RM, Nawaz S, Humml C, Velanac V, Radyushkin K, Goebbels S, Fischer TM, Franklin RJ, Lai C, Ehrenreich H, Birchmeier C, Schwab MH, Nave KA.

Neuron. 2008 Aug 28;59(4):581-95. doi: 10.1016/j.neuron.2008.06.028.

7.

Constitutively active Akt induces enhanced myelination in the CNS.

Flores AI, Narayanan SP, Morse EN, Shick HE, Yin X, Kidd G, Avila RL, Kirschner DA, Macklin WB.

J Neurosci. 2008 Jul 9;28(28):7174-83. doi: 10.1523/JNEUROSCI.0150-08.2008.

8.

ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.

Yamauchi J, Miyamoto Y, Chan JR, Tanoue A.

J Cell Biol. 2008 Apr 21;181(2):351-65. doi: 10.1083/jcb.200709033.

9.
10.

Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1.

Cao Z, Wu X, Yen L, Sweeney C, Carraway KL 3rd.

Mol Cell Biol. 2007 Mar;27(6):2180-8. Epub 2007 Jan 8.

11.

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

Atanasoski S, Scherer SS, Sirkowski E, Leone D, Garratt AN, Birchmeier C, Suter U.

J Neurosci. 2006 Feb 15;26(7):2124-31.

12.

Novel mechanism of interaction of p85 subunit of phosphatidylinositol 3-kinase and ErbB3 receptor-derived phosphotyrosyl peptides.

Suenaga A, Takada N, Hatakeyama M, Ichikawa M, Yu X, Tomii K, Okimoto N, Futatsugi N, Narumi T, Shirouzu M, Yokoyama S, Konagaya A, Taiji M.

J Biol Chem. 2005 Jan 14;280(2):1321-6. Epub 2004 Nov 1.

13.
14.

Neuregulin isoforms exhibit distinct patterns of ErbB family receptor activation.

Hobbs SS, Coffing SL, Le AT, Cameron EM, Williams EE, Andrew M, Blommel EN, Hammer RP, Chang H, Riese DJ 2nd.

Oncogene. 2002 Dec 5;21(55):8442-52.

15.

Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.

Qiu XB, Goldberg AL.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14843-8. Epub 2002 Oct 31. Erratum in: Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17220..

16.

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.

Ozcelik C, Erdmann B, Pilz B, Wettschureck N, Britsch S, Hübner N, Chien KR, Birchmeier C, Garratt AN.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8880-5. Epub 2002 Jun 18.

17.

ErbB2 is essential in the prevention of dilated cardiomyopathy.

Crone SA, Zhao YY, Fan L, Gu Y, Minamisawa S, Liu Y, Peterson KL, Chen J, Kahn R, Condorelli G, Ross J Jr, Chien KR, Lee KF.

Nat Med. 2002 May;8(5):459-65.

PMID:
11984589
18.

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.

Ren Z, Schaefer TS.

J Biol Chem. 2002 Oct 11;277(41):38486-93. Epub 2002 Apr 8.

19.

The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes.

Park SK, Miller R, Krane I, Vartanian T.

J Cell Biol. 2001 Sep 17;154(6):1245-58.

20.

Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor.

Hellyer NJ, Kim MS, Koland JG.

J Biol Chem. 2001 Nov 9;276(45):42153-61. Epub 2001 Sep 6.

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