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Items: 1 to 20 of 592

1.

The V2 receptor antagonist tolvaptan raises cytosolic calcium and prevents AQP2 trafficking and function: an in vitro and in vivo assessment.

Tamma G, Di Mise A, Ranieri M, Geller A, Tamma R, Zallone A, Valenti G.

J Cell Mol Med. 2017 Mar 21. doi: 10.1111/jcmm.13098. [Epub ahead of print]

2.

Elastic modulus and hydraulic permeability of MDCK monolayers.

Schulze KD, Zehnder SM, Urueña JM, Bhattacharjee T, Sawyer WG, Angelini TE.

J Biomech. 2017 Feb 28;53:210-213. doi: 10.1016/j.jbiomech.2017.01.016. Epub 2017 Jan 20.

PMID:
28173919
3.

Relationship between Passive Permeability and Molecular Polarity Using Block Relevance Analysis.

Goetz GH, Shalaeva M, Caron G, Ermondi G, Philippe L.

Mol Pharm. 2017 Feb 6;14(2):386-393. doi: 10.1021/acs.molpharmaceut.6b00724. Epub 2017 Jan 17.

PMID:
28035823
4.

Effect of Panax notoginseng saponins on the pharmacokinetics of aspirin in rats.

Tian Z, Pang H, Du S, Lu Y, Zhang L, Wu H, Guo S, Wang M, Zhang Q.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:136-143. doi: 10.1016/j.jchromb.2016.12.007. Epub 2016 Dec 6.

PMID:
27978468
5.

ADME studies and preliminary safety pharmacology of LDT5, a lead compound for the treatment of benign prostatic hyperplasia.

Noël F, Nascimento-Viana JB, Romeiro LA, Silva RO, Lemes LF, Oliveira AS, Giorno TB, Fernandes PD, Silva CL.

Braz J Med Biol Res. 2016;49(12):e5542. doi: 10.1590/1414-431X20165542.

6.

Effects of Osmolality on Paracellular Transport in MDCK II Cells.

Tokuda S, Hirai T, Furuse M.

PLoS One. 2016 Nov 17;11(11):e0166904. doi: 10.1371/journal.pone.0166904. eCollection 2016.

7.

Predicting Passive Permeability of Drug-like Molecules from Chemical Structure: Where Are We?

Broccatelli F, Salphati L, Plise E, Cheong J, Gobbi A, Lee ML, Aliagas I.

Mol Pharm. 2016 Dec 5;13(12):4199-4208. Epub 2016 Nov 11.

PMID:
27806577
8.

AQP2 Plasma Membrane Diffusion Is Altered by the Degree of AQP2-S256 Phosphorylation.

Arnspang EC, Login FH, Koffman JS, Sengupta P, Nejsum LN.

Int J Mol Sci. 2016 Oct 28;17(11). pii: E1804.

9.

Effects of P-glycoprotein on the intestine and blood-brain barrier transport of YZG-331, a promising sedative-hypnotic compound.

Liu Z, Mi J, Yang S, Zhao M, Li Y, Sheng L.

Eur J Pharmacol. 2016 Nov 15;791:339-347. doi: 10.1016/j.ejphar.2016.08.039. Epub 2016 Sep 7.

PMID:
27612629
10.

Pharmacokinetic characterization of anhuienoside C and its deglycosylated metabolites in rats.

Sun H, Liu H, Zhao H, Wang Y, Li YL, Ye WC, Wu B.

Xenobiotica. 2016 Oct 24:1-9. doi: 10.1080/00498254.2016.1241452. [Epub ahead of print]

PMID:
27662115
11.

The Role of Nanoparticle in Brain Permeability: An in-vitro BBB Model.

Nikandish N, Hosseinzadeh L, Hemati Azandaryani A, Derakhshandeh K.

Iran J Pharm Res. 2016 Spring;15(2):403-13.

12.

Circumvention of P-gp and MRP2 mediated efflux of lopinavir by a histidine based dipeptide prodrug.

Mandal A, Pal D, Mitra AK.

Int J Pharm. 2016 Oct 15;512(1):49-60. doi: 10.1016/j.ijpharm.2016.08.027. Epub 2016 Aug 16.

PMID:
27543355
13.
14.

Claudin-2-mediated cation and water transport share a common pore.

Rosenthal R, Günzel D, Krug SM, Schulzke JD, Fromm M, Yu AS.

Acta Physiol (Oxf). 2017 Feb;219(2):521-536. doi: 10.1111/apha.12742. Epub 2016 Jul 20.

PMID:
27359349
15.

TSPO Ligand-Methotrexate Prodrug Conjugates: Design, Synthesis, and Biological Evaluation.

Laquintana V, Denora N, Cutrignelli A, Perrone M, Iacobazzi RM, Annese C, Lopalco A, Lopedota AA, Franco M.

Int J Mol Sci. 2016 Jun 18;17(6). pii: E967. doi: 10.3390/ijms17060967.

16.

Isolation of a thiol-dependent serine protease in peanut and investigation of its role in the complement and the allergic reaction.

Javaux C, Stordeur P, Azarkan M, Mascart F, Baeyens-Volant D.

Mol Immunol. 2016 Jul;75:133-43. doi: 10.1016/j.molimm.2016.05.004. Epub 2016 Jun 7.

PMID:
27280846
17.

Advantage of the Dissolution/Permeation System for Estimating Oral Absorption of Drug Candidates in the Drug Discovery Stage.

Miyaji Y, Fujii Y, Takeyama S, Kawai Y, Kataoka M, Takahashi M, Yamashita S.

Mol Pharm. 2016 May 2;13(5):1564-74. doi: 10.1021/acs.molpharmaceut.6b00044. Epub 2016 Apr 13.

PMID:
27031624
18.

Core-matched encapsulation of an oleate prodrug into nanostructured lipid carriers with high drug loading capability to facilitate the oral delivery of docetaxel.

Sun B, Luo C, Li L, Wang M, Du Y, Di D, Zhang D, Ren G, Pan X, Fu Q, Sun J, He Z.

Colloids Surf B Biointerfaces. 2016 Jul 1;143:47-55. doi: 10.1016/j.colsurfb.2016.02.065. Epub 2016 Mar 2.

PMID:
27011346
19.

Absorption mechanism of oxymatrine in cultured Madin-Darby canine kidney cell monolayers.

Xiong XH, Huang LH, Zhong YM, Cheng XG, Cen MF, Wang GX, Zang LQ, Wang SJ.

Pharm Biol. 2016 Oct;54(10):2168-75. doi: 10.3109/13880209.2016.1149496. Epub 2016 Mar 17.

PMID:
26983455

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