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Items: 1 to 20 of 4364

1.

Frequent hypomorphic alleles account for a significant fraction of ABCA4 disease and distinguish it from age-related macular degeneration.

Zernant J, Lee W, Collison FT, Fishman GA, Sergeev YV, Schuerch K, Sparrow JR, Tsang SH, Allikmets R.

J Med Genet. 2017 Apr 26. pii: jmedgenet-2017-104540. doi: 10.1136/jmedgenet-2017-104540. [Epub ahead of print]

PMID:
28446513
2.

Retinal and Circulating miRNAs in Age-Related Macular Degeneration: An <i>In vivo</i> Animal and Human Study.

Romano GL, Platania CBM, Drago F, Salomone S, Ragusa M, Barbagallo C, Di Pietro C, Purrello M, Reibaldi M, Avitabile T, Longo A, Bucolo C.

Front Pharmacol. 2017 Mar 30;8:168. doi: 10.3389/fphar.2017.00168. eCollection 2017.

3.

Genetic variants in microRNAs and their binding sites within gene 3'UTRs associate with susceptibility to age-related macular degeneration (AMD).

Ghanbari M, Erkeland SJ, Xu L, Colijn JM, Franco OH, Dehghan A, Klaver CC, Meester-Smoor MA.

Hum Mutat. 2017 Apr 10. doi: 10.1002/humu.23226. [Epub ahead of print]

PMID:
28397307
4.

Multimodal Regulation Orchestrates Normal and Complex Disease States in the Retina.

Olivares AM, Jelcick AS, Reinecke J, Leehy B, Haider A, Morrison MA, Cheng L, Chen DF, DeAngelis MM, Haider NB.

Sci Rep. 2017 Apr 6;7(1):690. doi: 10.1038/s41598-017-00788-3.

5.

DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD).

Hyttinen JMT, Błasiak J, Niittykoski M, Kinnunen K, Kauppinen A, Salminen A, Kaarniranta K.

Ageing Res Rev. 2017 Mar 27;36:64-77. doi: 10.1016/j.arr.2017.03.006. [Epub ahead of print] Review.

PMID:
28351686
6.

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K; International AMD Genomics Consortium (IAMDGC)., Heid IM, Weber BH.

Genome Med. 2017 Mar 27;9(1):29. doi: 10.1186/s13073-017-0418-0.

7.

miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD).

SanGiovanni JP, SanGiovanni PM, Sapieha P, De Guire V.

Clin Chem Lab Med. 2017 May 1;55(5):763-775. doi: 10.1515/cclm-2016-0898. Review.

PMID:
28343170
8.

Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores.

Ding Y, Liu Y, Yan Q, Fritsche LG, Cook RJ, Clemons T, Ratnapriya R, Klein ML, Abecasis GR, Swaroop A, Chew EY, Weeks DE, Chen W.

Genetics. 2017 Mar 24. pii: genetics.116.196998. doi: 10.1534/genetics.116.196998. [Epub ahead of print]

9.

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration.

Tan PL, Garrett ME, Willer JR, Campochiaro PA, Campochiaro B, Zack DJ, Ashley-Koch AE, Katsanis N.

Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1570-1576. doi: 10.1167/iovs.16-20867.

PMID:
28282489
10.

Possible Interventions to Modify Aging.

Libertini G, Ferrara N.

Biochemistry (Mosc). 2016 Dec;81(12):1413-1428. doi: 10.1134/S0006297916120038.

11.

Tamoxifen Provides Structural and Functional Rescue in Murine Models of Photoreceptor Degeneration.

Wang X, Zhao L, Zhang Y, Ma W, Gonzalez SR, Fan J, Kretschmer F, Badea TC, Qian HH, Wong WT.

J Neurosci. 2017 Mar 22;37(12):3294-3310. doi: 10.1523/JNEUROSCI.2717-16.2017. Epub 2017 Feb 24.

PMID:
28235894
12.

Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration.

Qi X, Pay SL, Yan Y, Thomas J Jr, Lewin AS, Chang LJ, Grant MB, Boulton ME.

Mol Ther. 2017 Apr 5;25(4):917-927. doi: 10.1016/j.ymthe.2017.01.015. Epub 2017 Feb 13.

13.

Genetic risk models: Influence of model size on risk estimates and precision.

Shan Y, Tromp G, Kuivaniemi H, Smelser DT, Verma SS, Ritchie MD, Elmore JR, Carey DJ, Conley YP, Gorin MB, Weeks DE.

Genet Epidemiol. 2017 May;41(4):282-296. doi: 10.1002/gepi.22035. Epub 2017 Feb 15.

PMID:
28198095
14.

Disturbed Matrix Metalloproteinase Pathway in Both Age-Related Macular Degeneration and Alzheimer's Disease.

Hussain AA, Lee Y, Zhang JJ, Francis PT, Marshall J.

J Neurodegener Dis. 2017;2017:4810232. doi: 10.1155/2017/4810232. Epub 2017 Jan 18.

15.

Contributions of age-related alterations of the retinal pigment epithelium and of glia to the AMD-like pathology in OXYS rats.

Telegina DV, Kozhevnikova OS, Bayborodin SI, Kolosova NG.

Sci Rep. 2017 Jan 30;7:41533. doi: 10.1038/srep41533.

16.

Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients.

Bardak H, Gunay M, Ercalik Y, Bardak Y, Ozbas H, Bagci O.

Genet Mol Res. 2017 Jan 23;16(1). doi: 10.4238/gmr16019135.

PMID:
28128407
17.

Genes of susceptibility to early neurodegenerative changes in the rat retina and brain: analysis by means of congenic strains.

Korbolina EE, Zhdankina AA, Fursova AZ, Kozhevnikova OS, Kolosova NG.

BMC Genet. 2016 Dec 22;17(Suppl 3):153. doi: 10.1186/s12863-016-0461-7.

18.

Hesperetin protects against H2O2-triggered oxidative damage via upregulation of the Keap1-Nrf2/HO-1 signal pathway in ARPE-19 cells.

Zhu C, Dong Y, Liu H, Ren H, Cui Z.

Biomed Pharmacother. 2017 Apr;88:124-133. doi: 10.1016/j.biopha.2016.11.089. Epub 2017 Jan 16.

PMID:
28103505
19.

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator.

Micklisch S, Lin Y, Jacob S, Karlstetter M, Dannhausen K, Dasari P, von der Heide M, Dahse HM, Schmölz L, Grassmann F, Alene M, Fauser S, Neumann H, Lorkowski S, Pauly D, Weber BH, Joussen AM, Langmann T, Zipfel PF, Skerka C.

J Neuroinflammation. 2017 Jan 5;14(1):4. doi: 10.1186/s12974-016-0776-3.

20.

Characterization of tubular liquid crystal structure in embryonic stem cell derived embryoid bodies.

Xu M, Jones OD, Wang L, Zhou X, Davis HG, Bryant JL, Ma J, Isaacs WB, Xu X.

Cell Biosci. 2017 Jan 3;7:3. doi: 10.1186/s13578-016-0130-6. eCollection 2017.

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