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Items: 1 to 20 of 179

1.

Control of mitochondrial pH by uncoupling protein 4 in astrocytes promotes neuronal survival.

Perreten Lambert H, Zenger M, Azarias G, Chatton JY, Magistretti PJ, Lengacher S.

J Biol Chem. 2014 Nov 7;289(45):31014-28. doi: 10.1074/jbc.M114.570879. Epub 2014 Sep 18.

2.

Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.

Liu D, Chan SL, de Souza-Pinto NC, Slevin JR, Wersto RP, Zhan M, Mustafa K, de Cabo R, Mattson MP.

Neuromolecular Med. 2006;8(3):389-414.

PMID:
16775390
3.

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity.

Kwok KH, Ho PW, Chu AC, Ho JW, Liu HF, Yiu DC, Chan KH, Kung MH, Ramsden DB, Ho SL.

Free Radic Biol Med. 2010 Sep 15;49(6):1023-35. doi: 10.1016/j.freeradbiomed.2010.06.017. Epub 2010 Jun 19.

PMID:
20600837
4.

Mitochondrial UCP4 attenuates MPP+ - and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression.

Chu AC, Ho PW, Kwok KH, Ho JW, Chan KH, Liu HF, Kung MH, Ramsden DB, Ho SL.

Free Radic Biol Med. 2009 Mar 15;46(6):810-20. doi: 10.1016/j.freeradbiomed.2008.12.015. Epub 2008 Dec 25.

PMID:
19150400
5.

Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells.

Chan SL, Liu D, Kyriazis GA, Bagsiyao P, Ouyang X, Mattson MP.

J Biol Chem. 2006 Dec 8;281(49):37391-403. Epub 2006 Oct 11.

6.

Mitochondrial uncoupling proteins in the central nervous system.

Kim-Han JS, Dugan LL.

Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1173-81. Review.

PMID:
16115020
7.

Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5.

Hoang T, Smith MD, Jelokhani-Niaraki M.

Biochemistry. 2012 May 15;51(19):4004-14. doi: 10.1021/bi3003378. Epub 2012 Apr 27.

PMID:
22524567
8.

Mitochondrial dysfunction is induced by the overexpression of UCP4 in 3T3-L1 adipocytes.

Gao CL, Zhu JG, Zhao YP, Chen XH, Ji CB, Zhang CM, Zhu C, Xia ZK, Peng YZ, Guo XR.

Int J Mol Med. 2010 Jan;25(1):71-80.

PMID:
19956904
9.
10.

Differentiation-Dependent Energy Production and Metabolite Utilization: A Comparative Study on Neural Stem Cells, Neurons, and Astrocytes.

Jády AG, Nagy ÁM, Kőhidi T, Ferenczi S, Tretter L, Madarász E.

Stem Cells Dev. 2016 Jul 1;25(13):995-1005. doi: 10.1089/scd.2015.0388. Epub 2016 Jun 7.

11.

Mitochondrial uncoupling protein-2 (UCP2) mediates leptin protection against MPP+ toxicity in neuronal cells.

Ho PW, Liu HF, Ho JW, Zhang WY, Chu AC, Kwok KH, Ge X, Chan KH, Ramsden DB, Ho SL.

Neurotox Res. 2010 May;17(4):332-43. doi: 10.1007/s12640-009-9109-y. Epub 2009 Sep 10.

12.

Superresolution microscopy reveals spatial separation of UCP4 and F0F1-ATP synthase in neuronal mitochondria.

Klotzsch E, Smorodchenko A, Löfler L, Moldzio R, Parkinson E, Schütz GJ, Pohl EE.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):130-5. doi: 10.1073/pnas.1415261112. Epub 2014 Dec 22.

13.

Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells.

Ho PW, Ho JW, Tse HM, So DH, Yiu DC, Liu HF, Chan KH, Kung MH, Ramsden DB, Ho SL.

PLoS One. 2012;7(2):e32810. doi: 10.1371/journal.pone.0032810. Epub 2012 Feb 29.

14.

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

Hyslop PA, Hinshaw DB, Halsey WA Jr, Schraufstätter IU, Sauerheber RD, Spragg RG, Jackson JH, Cochrane CG.

J Biol Chem. 1988 Feb 5;263(4):1665-75.

15.

Localization of the mitochondrial uncoupling protein family in the rat inner ear.

Kitahara T, Li HS, Balaban CD.

Hear Res. 2004 Oct;196(1-2):39-48.

PMID:
15464300
16.

Mitochondrial uncoupling protein 1 expressed in the heart of transgenic mice protects against ischemic-reperfusion damage.

Hoerter J, Gonzalez-Barroso MD, Couplan E, Mateo P, Gelly C, Cassard-Doulcier AM, Diolez P, Bouillaud F.

Circulation. 2004 Aug 3;110(5):528-33. Epub 2004 Jul 19.

PMID:
15262832
17.

Glycolysis and oxidative phosphorylation in neurons and astrocytes during network activity in hippocampal slices.

Ivanov AI, Malkov AE, Waseem T, Mukhtarov M, Buldakova S, Gubkina O, Zilberter M, Zilberter Y.

J Cereb Blood Flow Metab. 2014 Mar;34(3):397-407. doi: 10.1038/jcbfm.2013.222. Epub 2013 Dec 11.

18.

Hydrogen peroxide regulates the mitochondrial content of uncoupling protein 5 in colon cancer cells.

Santandreu FM, Valle A, Fernández de Mattos S, Roca P, Oliver J.

Cell Physiol Biochem. 2009;24(5-6):379-90. doi: 10.1159/000257430. Epub 2009 Nov 4.

19.

Cloning, ontogenesis, and localization of an atypical uncoupling protein 4 in Xenopus laevis.

Keller PA, Lehr L, Giacobino JP, Charnay Y, Assimacopoulos-Jeannet F, Giovannini N.

Physiol Genomics. 2005 Aug 11;22(3):339-45. Epub 2005 May 24.

PMID:
15914580
20.

Methyl-4-phenylpyridinium ion modulates expression of mitochondrial uncoupling proteins 2, 4, and 5 in catecholaminergic (SK-N-SH) cells.

Ho PW, Chan DY, Kwok KH, Chu AC, Ho JW, Kung MH, Ramsden DB, Ho SL.

J Neurosci Res. 2005 Jul 15;81(2):261-8.

PMID:
15948157

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