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Items: 1 to 20 of 88

1.

Hepatitis C virus sensitizes host cells to TRAIL-induced apoptosis by up-regulating DR4 and DR5 via a MEK1-dependent pathway.

Deng Z, Yan H, Hu J, Zhang S, Peng P, Liu Q, Guo D.

PLoS One. 2012;7(5):e37700. doi: 10.1371/journal.pone.0037700. Epub 2012 May 25.

2.

TRAIL enhances apoptosis of human hepatocellular carcinoma cells sensitized by hepatitis C virus infection: therapeutic implications.

Jang JY, Kim SJ, Cho EK, Jeong SW, Park EJ, Lee WC, Lee SH, Kim SG, Kim YS, Kim HS, Kim BS, Lin W, Chung RT.

PLoS One. 2014 Jun 13;9(6):e98171. doi: 10.1371/journal.pone.0098171. eCollection 2014.

3.

Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.

Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS.

J Cell Biochem. 2008 Dec 15;105(6):1386-98. doi: 10.1002/jcb.21958.

PMID:
18980244
4.

Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DR5 up-regulation: involvement of Ca(2+) influx.

Moon DO, Kang CH, Kang SH, Choi YH, Hyun JW, Chang WY, Kang HK, Koh YS, Maeng YH, Kim YR, Kim GY.

Toxicol Appl Pharmacol. 2012 Feb 15;259(1):87-95. doi: 10.1016/j.taap.2011.12.010. Epub 2011 Dec 19.

PMID:
22200406
5.

Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-kappaB inactivation.

Moon DO, Kim MO, Choi YH, Kim GY.

Mol Cancer Ther. 2010 Jun;9(6):1583-95. doi: 10.1158/1535-7163.MCT-09-0942. Epub 2010 Jun 1.

6.

Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, Park JW, Choi KS, Kwon TK.

Free Radic Biol Med. 2008 Mar 15;44(6):1055-68. doi: 10.1016/j.freeradbiomed.2007.12.001. Epub 2007 Dec 8.

PMID:
18164688
7.

5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.

Yang JF, Cao JG, Tian L, Liu F.

Cancer Chemother Pharmacol. 2012 Jan;69(1):195-206. doi: 10.1007/s00280-011-1686-9. Epub 2011 Jun 10.

PMID:
21660448
8.
9.

Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.

Hetschko H, Voss V, Seifert V, Prehn JH, Kögel D.

FEBS J. 2008 Apr;275(8):1925-36. doi: 10.1111/j.1742-4658.2008.06351.x. Epub 2008 Mar 13.

11.

Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cells.

Oh Y, Jeon YJ, Hong GS, Kim I, Woo HN, Jung YK.

Cell Death Differ. 2012 Jul;19(7):1196-207. doi: 10.1038/cdd.2011.209. Epub 2012 Jan 13.

12.

Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRAIL-induced apoptosis.

Ohtsuki T, Kikuchi H, Koyano T, Kowithayakorn T, Sakai T, Ishibashi M.

Bioorg Med Chem. 2009 Sep 15;17(18):6748-54. doi: 10.1016/j.bmc.2009.07.041. Epub 2009 Jul 24.

PMID:
19682913
13.

beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.

Kim MO, Moon DO, Kang CH, Kwon TK, Choi YH, Kim GY.

Mol Cancer Ther. 2010 Apr;9(4):833-43. doi: 10.1158/1535-7163.MCT-09-0610. Epub 2010 Mar 30.

14.
15.

Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system.

Zhu H, Dong H, Eksioglu E, Hemming A, Cao M, Crawford JM, Nelson DR, Liu C.

Gastroenterology. 2007 Nov;133(5):1649-59. Epub 2007 Sep 16.

PMID:
17983809
16.

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.

Mahalingam D, Natoni A, Keane M, Samali A, Szegezdi E.

Br J Cancer. 2010 Feb 16;102(4):754-64. doi: 10.1038/sj.bjc.6605545. Epub 2010 Jan 19.

18.

TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5.

Zhang Y, Zhang B.

Mol Cancer Res. 2008 Dec;6(12):1861-71. doi: 10.1158/1541-7786.MCR-08-0313.

19.

Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.

Zhang X, Inukai T, Hirose K, Akahane K, Kuroda I, Honna-Oshiro H, Kagami K, Goi K, Nakamura K, Kobayashi M, Endo M, Yagita H, Kurosawa H, Thomas Look A, Honda H, Inaba T, Nakazawa S, Sugita K.

Leukemia. 2012 Dec;26(12):2483-93. doi: 10.1038/leu.2012.139. Epub 2012 May 30.

PMID:
22743623
20.

Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5.

Chen CY, Yiin SJ, Hsu JL, Wang WC, Lin SC, Chern CL.

J Agric Food Chem. 2012 Apr 4;60(13):3533-9. doi: 10.1021/jf2051224. Epub 2012 Mar 21.

PMID:
22400995

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