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Items: 1 to 20 of 157

1.

The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A.

Helbig KJ, Eyre NS, Yip E, Narayana S, Li K, Fiches G, McCartney EM, Jangra RK, Lemon SM, Beard MR.

Hepatology. 2011 Nov;54(5):1506-17. doi: 10.1002/hep.24542.

2.

Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.

Wang S, Wu X, Pan T, Song W, Wang Y, Zhang F, Yuan Z.

J Gen Virol. 2012 Jan;93(Pt 1):83-92. doi: 10.1099/vir.0.033860-0. Epub 2011 Sep 28.

PMID:
21957124
3.

The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix.

Hinson ER, Cresswell P.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20452-7. doi: 10.1073/pnas.0911679106. Epub 2009 Nov 17.

4.

Localization determines function: N-terminally truncated NS5A fragments accumulate in the nucleus and impair HCV replication.

Sauter D, Himmelsbach K, Kriegs M, Carvajal Yepes M, Hildt E.

J Hepatol. 2009 May;50(5):861-71. doi: 10.1016/j.jhep.2008.11.024. Epub 2009 Jan 31.

PMID:
19307038
5.

Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.

Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M.

PLoS Pathog. 2013;9(4):e1003302. doi: 10.1371/journal.ppat.1003302. Epub 2013 Apr 11.

6.

Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector.

Helbig KJ, Lau DT, Semendric L, Harley HA, Beard MR.

Hepatology. 2005 Sep;42(3):702-10.

PMID:
16108059
7.

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y.

J Virol. 2005 Nov;79(21):13473-82.

8.

Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH.

J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9.

9.

Interaction between Nonstructural Proteins NS4B and NS5A Is Essential for Proper NS5A Localization and Hepatitis C Virus RNA Replication.

Biswas A, Treadaway J, Tellinghuisen TL.

J Virol. 2016 Jul 27;90(16):7205-7218. doi: 10.1128/JVI.00037-16. Print 2016 Aug 15.

10.

GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication.

Xu G, Xin X, Zheng C.

PLoS One. 2013 Nov 4;8(11):e78195. doi: 10.1371/journal.pone.0078195. eCollection 2013.

11.

Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus.

Jiang D, Guo H, Xu C, Chang J, Gu B, Wang L, Block TM, Guo JT.

J Virol. 2008 Feb;82(4):1665-78. Epub 2007 Dec 12.

12.

Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells.

Hou W, Tian Q, Zheng J, Bonkovsky HL.

Gastroenterology. 2010 May;138(5):1909-19. doi: 10.1053/j.gastro.2009.11.001. Epub 2009 Nov 10.

13.

Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication.

Bürckstümmer T, Kriegs M, Lupberger J, Pauli EK, Schmittel S, Hildt E.

FEBS Lett. 2006 Jan 23;580(2):575-80. Epub 2005 Dec 29.

14.

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

Huang Y, Staschke K, De Francesco R, Tan SL.

Virology. 2007 Jul 20;364(1):1-9. Epub 2007 Apr 2. Review.

15.

Seed sequence-matched controls reveal limitations of small interfering RNA knockdown in functional and structural studies of hepatitis C virus NS5A-MOBKL1B interaction.

Chung HY, Gu M, Buehler E, MacDonald MR, Rice CM.

J Virol. 2014 Oct;88(19):11022-33. doi: 10.1128/JVI.01582-14. Epub 2014 Jul 16.

16.

Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.

Moradpour D, Evans MJ, Gosert R, Yuan Z, Blum HE, Goff SP, Lindenbach BD, Rice CM.

J Virol. 2004 Jul;78(14):7400-9.

17.

Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.

Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T.

J Virol. 2014 Jul;88(13):7541-55. doi: 10.1128/JVI.03170-13. Epub 2014 Apr 23.

18.

Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions.

Goonawardane N, Gebhardt A, Bartlett C, Pichlmair A, Harris M.

J Virol. 2017 Aug 10;91(17). pii: e00805-17. doi: 10.1128/JVI.00805-17. Print 2017 Sep 1.

19.

Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes.

Maqbool MA, Imache MR, Higgs MR, Carmouse S, Pawlotsky JM, Lerat H.

J Virol. 2013 May;87(10):5523-39. doi: 10.1128/JVI.00585-12. Epub 2013 Mar 6. Erratum in: J Virol. 2013 Sep;87(17):9963.

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