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Items: 1 to 20 of 121

1.

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.

Datta S, Hazari S, Chandra PK, Samara M, Poat B, Gunduz F, Wimley WC, Hauser H, Koster M, Lamaze C, Balart LA, Garry RF, Dash S.

Virol J. 2011 Jul 14;8:351. doi: 10.1186/1743-422X-8-351.

2.

Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture.

Gunduz F, Aboulnasr FM, Chandra PK, Hazari S, Poat B, Baker DP, Balart LA, Dash S.

Virol J. 2012 Aug 3;9:143. doi: 10.1186/1743-422X-9-143.

3.

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway.

Hazari S, Chandra PK, Poat B, Datta S, Garry RF, Foster TP, Kousoulas G, Wakita T, Dash S.

Virol J. 2010 Feb 11;7:36. doi: 10.1186/1743-422X-7-36.

4.

Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S.

PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. eCollection 2015.

5.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

6.

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.

Poat B, Hazari S, Chandra PK, Gunduz F, Alvarez X, Balart LA, Garry RF, Dash S.

Virol J. 2010 Oct 12;7:265. doi: 10.1186/1743-422X-7-265.

7.

SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.

Poat B, Hazari S, Chandra PK, Gunduz F, Balart LA, Alvarez X, Dash S.

PLoS One. 2010 Sep 30;5(9). pii: e13117. doi: 10.1371/journal.pone.0013117.

8.

Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in hepatitis C virus replicon.

Hazari S, Taylor L, Haque S, Garry RF, Florman S, Luftig R, Regenstein F, Dash S.

Virol J. 2007 Sep 18;4:89.

9.

IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S.

PLoS One. 2015 Dec 11;10(12):e0141655. doi: 10.1371/journal.pone.0141655. eCollection 2015.

10.

Inhibition of STAT Pathway Impairs Anti-Hepatitis C Virus Effect of Interferon Alpha.

Zhao LJ, He SF, Liu Y, Zhao P, Bian ZQ, Qi ZT.

Cell Physiol Biochem. 2016;40(1-2):77-90. Epub 2016 Nov 18.

11.

Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.

Han T, Wan Y, Wang J, Zhao P, Yuan Y, Wang L, She Y, Broering R, Lu M, Ye L, Zhu Y.

J Immunol. 2015 Mar 15;194(6):2757-68. doi: 10.4049/jimmunol.1400583. Epub 2015 Feb 13.

12.

Hepatitis C virus core protein-induced miR-93-5p up-regulation inhibits interferon signaling pathway by targeting IFNAR1.

He CL, Liu M, Tan ZX, Hu YJ, Zhang QY, Kuang XM, Kong WL, Mao Q.

World J Gastroenterol. 2018 Jan 14;24(2):226-236. doi: 10.3748/wjg.v24.i2.226.

13.
14.

Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

Chandra PK, Gunduz F, Hazari S, Kurt R, Panigrahi R, Poat B, Bruce D, Cohen AJ, Bohorquez HE, Carmody I, Loss G, Balart LA, Wu T, Dash S.

PLoS One. 2014 Sep 29;9(9):e108616. doi: 10.1371/journal.pone.0108616. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114456. Behorquez, Humberto E [corrected to Bohorquez, Humberto E].

15.

HCV infection selectively impairs type I but not type III IFN signaling.

Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S.

Am J Pathol. 2014 Jan;184(1):214-29. doi: 10.1016/j.ajpath.2013.10.005. Epub 2013 Nov 9.

16.

Activation of interferon-stimulated response element in huh-7 cells replicating hepatitis C virus subgenomic RNA.

Pai M, Prabhu R, Panebra A, Nangle S, Haque S, Bastian F, Garry R, Agrawal K, Goodbourn S, Dash S.

Intervirology. 2005;48(5):301-11.

PMID:
15956798
17.

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies.

Larrea E, Aldabe R, Molano E, Fernandez-Rodriguez CM, Ametzazurra A, Civeira MP, Prieto J.

Gut. 2006 Aug;55(8):1188-96. Epub 2005 Aug 24.

18.

Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN.

PLoS One. 2010 Nov 10;5(11):e13927. doi: 10.1371/journal.pone.0013927.

19.
20.

Alcohol impairs interferon signaling and enhances full cycle hepatitis C virus JFH-1 infection of human hepatocytes.

Ye L, Wang S, Wang X, Zhou Y, Li J, Persidsky Y, Ho W.

Drug Alcohol Depend. 2010 Nov 1;112(1-2):107-16. doi: 10.1016/j.drugalcdep.2010.05.008. Epub 2010 Jun 20.

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