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Items: 1 to 20 of 128

1.

Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway.

Tacke RS, Tosello-Trampont A, Nguyen V, Mullins DW, Hahn YS.

J Biol Chem. 2011 Mar 25;286(12):10847-55. doi: 10.1074/jbc.M110.217653. Epub 2011 Jan 31.

2.

Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling.

Zhai N, Li H, Song H, Yang Y, Cui A, Li T, Niu J, Crispe IN, Su L, Tu Z.

PLoS One. 2017 Jan 23;12(1):e0170516. doi: 10.1371/journal.pone.0170516. eCollection 2017.

3.

HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways.

Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, Ma C, Yang L, Gao X, Li W, Liu J, Wei L.

Oncotarget. 2016 Jun 7;7(23):33796-808. doi: 10.18632/oncotarget.9304.

4.

Hepatitis C virus regulates the production of monocytic myeloid-derived suppressor cells from peripheral blood mononuclear cells through PI3K pathway and autocrine signaling.

Pang X, Song H, Zhang Q, Tu Z, Niu J.

Clin Immunol. 2016 Mar;164:57-64. doi: 10.1016/j.clim.2016.01.014. Epub 2016 Jan 25.

PMID:
26821305
5.

Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli.

Hosui A, Ohkawa K, Ishida H, Sato A, Nakanishi F, Ueda K, Takehara T, Kasahara A, Sasaki Y, Hori M, Hayashi N.

J Biol Chem. 2003 Aug 1;278(31):28562-71. Epub 2003 May 22.

6.

Improved dendritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10.

Díaz-Valdés N, Manterola L, Belsúe V, Riezu-Boj JI, Larrea E, Echeverria I, Llópiz D, López-Sagaseta J, Lerat H, Pawlotsky JM, Prieto J, Lasarte JJ, Borrás-Cuesta F, Sarobe P.

Hepatology. 2011 Jan;53(1):23-31. doi: 10.1002/hep.23980. Epub 2010 Dec 13.

7.

Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.

Dolganiuc A, Kodys K, Kopasz A, Marshall C, Do T, Romics L Jr, Mandrekar P, Zapp M, Szabo G.

J Immunol. 2003 Jun 1;170(11):5615-24.

8.

Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection.

Zhang Y, Ma CJ, Wang JM, Ji XJ, Wu XY, Jia ZS, Moorman JP, Yao ZQ.

PLoS One. 2011;6(5):e19664. doi: 10.1371/journal.pone.0019664. Epub 2011 May 26.

9.

Hepatitis C virus-induced myeloid-derived suppressor cells regulate T-cell differentiation and function via the signal transducer and activator of transcription 3 pathway.

Ren JP, Zhao J, Dai J, Griffin JW, Wang L, Wu XY, Morrison ZD, Li GY, El Gazzar M, Ning SB, Moorman JP, Yao ZQ.

Immunology. 2016 Aug;148(4):377-86. doi: 10.1111/imm.12616. Epub 2016 Jun 22.

10.

HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon.

Chattergoon MA, Latanich R, Quinn J, Winter ME, Buckheit RW 3rd, Blankson JN, Pardoll D, Cox AL.

PLoS Pathog. 2014 May 1;10(5):e1004082. doi: 10.1371/journal.ppat.1004082. eCollection 2014 May.

11.

HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway.

Zhang Q, Wang Y, Zhai N, Song H, Li H, Yang Y, Li T, Guo X, Chi B, Niu J, Crispe IN, Su L, Tu Z.

Sci Rep. 2016 Oct 27;6:36160. doi: 10.1038/srep36160.

12.

IL-10 plays a central regulatory role in the cytokines induced by hepatitis C virus core protein and polyinosinic acid:polycytodylic acid.

Pang X, Wang Z, Zhai N, Zhang Q, Song H, Zhang Y, Li T, Li H, Su L, Niu J, Tu Z.

Int Immunopharmacol. 2016 Sep;38:284-90. doi: 10.1016/j.intimp.2016.06.013. Epub 2016 Jun 21.

PMID:
27337528
13.
14.

Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

Chang S, Dolganiuc A, Szabo G.

J Leukoc Biol. 2007 Sep;82(3):479-87. Epub 2007 Jun 26.

PMID:
17595379
15.

Hepatitis C virus core protein reduces CD8+ T-cell proliferation, perforin production and degranulation but increases STAT5 activation.

Khan ST, Karges W, Cooper CL, Crawley AM.

Immunology. 2018 May;154(1):156-165. doi: 10.1111/imm.12882. Epub 2018 Jan 25.

16.

HIV-1 gp120 activates the STAT3/interleukin-6 axis in primary human monocyte-derived dendritic cells.

Del Cornò M, Donninelli G, Varano B, Da Sacco L, Masotti A, Gessani S.

J Virol. 2014 Oct;88(19):11045-55. doi: 10.1128/JVI.00307-14. Epub 2014 Jul 9.

17.
18.

Hepatitis C virus core protein induces homotolerance and cross-tolerance to Toll-like receptor ligands by activation of Toll-like receptor 2.

Chung H, Watanabe T, Kudo M, Chiba T.

J Infect Dis. 2010 Sep 15;202(6):853-61. doi: 10.1086/655812.

PMID:
20677943
19.

T-bet-mediated Tim-3 expression dampens monocyte function during chronic hepatitis C virus infection.

Yi W, Zhang P, Liang Y, Zhou Y, Shen H, Fan C, Moorman JP, Yao ZQ, Jia Z, Zhang Y.

Immunology. 2017 Mar;150(3):301-311. doi: 10.1111/imm.12686. Epub 2016 Dec 7.

20.

Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.

Dolganiuc A, Chang S, Kodys K, Mandrekar P, Bakis G, Cormier M, Szabo G.

J Immunol. 2006 Nov 15;177(10):6758-68.

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