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Items: 1 to 20 of 63

1.

Receptor tyrosine kinase inhibitors block multiple steps of influenza a virus replication.

Kumar N, Liang Y, Parslow TG, Liang Y.

J Virol. 2011 Mar;85(6):2818-27. doi: 10.1128/JVI.01969-10. Epub 2011 Jan 5.

2.

Receptor tyrosine kinase inhibitors that block replication of influenza a and other viruses.

Kumar N, Sharma NR, Ly H, Parslow TG, Liang Y.

Antimicrob Agents Chemother. 2011 Dec;55(12):5553-9. doi: 10.1128/AAC.00725-11. Epub 2011 Sep 19.

3.

Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo.

Perwitasari O, Johnson S, Yan X, Howerth E, Shacham S, Landesman Y, Baloglu E, McCauley D, Tamir S, Tompkins SM, Tripp RA.

J Virol. 2014 Sep 1;88(17):10228-43. doi: 10.1128/JVI.01774-14. Epub 2014 Jun 25.

4.

A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis.

Martinez-Gil L, Alamares-Sapuay JG, Ramana Reddy MV, Goff PH, Premkumar Reddy E, Palese P.

Antiviral Res. 2013 Oct;100(1):29-37. doi: 10.1016/j.antiviral.2013.07.010. Epub 2013 Jul 24.

PMID:
23891991
5.

14-Deoxy-11,12-dehydroandrographolide exerts anti-influenza A virus activity and inhibits replication of H5N1 virus by restraining nuclear export of viral ribonucleoprotein complexes.

Cai W, Li Y, Chen S, Wang M, Zhang A, Zhou H, Chen H, Jin M.

Antiviral Res. 2015 Jun;118:82-92. doi: 10.1016/j.antiviral.2015.03.008. Epub 2015 Mar 20.

PMID:
25800824
6.

A new class of synthetic anti-lipopolysaccharide peptides inhibits influenza A virus replication by blocking cellular attachment.

Hoffmann J, Schneider C, Heinbockel L, Brandenburg K, Reimer R, Gabriel G.

Antiviral Res. 2014 Apr;104:23-33. doi: 10.1016/j.antiviral.2014.01.015. Epub 2014 Jan 30.

PMID:
24486207
7.

Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication.

Slaine PD, Kleer M, Smith NK, Khaperskyy DA, McCormick C.

Viruses. 2017 Dec 18;9(12). pii: E388. doi: 10.3390/v9120388.

8.

Cyclosporin A inhibits the influenza virus replication through cyclophilin A-dependent and -independent pathways.

Liu X, Zhao Z, Li Z, Xu C, Sun L, Chen J, Liu W.

PLoS One. 2012;7(5):e37277. doi: 10.1371/journal.pone.0037277. Epub 2012 May 15.

9.

Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus.

Alamares-Sapuay JG, Martinez-Gil L, Stertz S, Miller MS, Shaw ML, Palese P.

J Virol. 2013 May;87(10):6020-6. doi: 10.1128/JVI.01258-12. Epub 2013 Mar 13.

10.

Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity.

Sasaki Y, Kakisaka M, Chutiwitoonchai N, Tajima S, Hikono H, Saito T, Aida Y.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):49-54. doi: 10.1016/j.bbrc.2014.05.058. Epub 2014 May 22.

PMID:
24858693
11.

NF-kappaB signaling differentially regulates influenza virus RNA synthesis.

Kumar N, Xin ZT, Liang Y, Ly H, Liang Y.

J Virol. 2008 Oct;82(20):9880-9. doi: 10.1128/JVI.00909-08. Epub 2008 Aug 13.

12.

Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals.

Heldt FS, Frensing T, Pflugmacher A, Gröpler R, Peschel B, Reichl U.

PLoS Comput Biol. 2013;9(11):e1003372. doi: 10.1371/journal.pcbi.1003372. Epub 2013 Nov 21.

13.

Novel influenza virus NS1 antagonists block replication and restore innate immune function.

Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA.

J Virol. 2009 Feb;83(4):1881-91. doi: 10.1128/JVI.01805-08. Epub 2008 Dec 3.

14.

A natural component from Euphorbia humifusa Willd displays novel, broad-spectrum anti-influenza activity by blocking nuclear export of viral ribonucleoprotein.

Chang SY, Park JH, Kim YH, Kang JS, Min JY.

Biochem Biophys Res Commun. 2016 Mar 4;471(2):282-9. doi: 10.1016/j.bbrc.2016.01.123. Epub 2016 Feb 3.

PMID:
26850850
15.

Human host factors required for influenza virus replication.

König R, Stertz S, Zhou Y, Inoue A, Hoffmann HH, Bhattacharyya S, Alamares JG, Tscherne DM, Ortigoza MB, Liang Y, Gao Q, Andrews SE, Bandyopadhyay S, De Jesus P, Tu BP, Pache L, Shih C, Orth A, Bonamy G, Miraglia L, Ideker T, García-Sastre A, Young JA, Palese P, Shaw ML, Chanda SK.

Nature. 2010 Feb 11;463(7282):813-7. doi: 10.1038/nature08699.

16.

Prostaglandin A1 inhibits avian influenza virus replication at a postentry level: Effect on virus protein synthesis and NF-κB activity.

Carta S, La Frazia S, Donatelli I, Puzelli S, Rossi A, Santoro MG.

Prostaglandins Leukot Essent Fatty Acids. 2014 Dec;91(6):311-23. doi: 10.1016/j.plefa.2014.07.009. Epub 2014 Jul 24.

PMID:
25151089
17.

Inhibition of Akt kinase activity suppresses entry and replication of influenza virus.

Hirata N, Suizu F, Matsuda-Lennikov M, Edamura T, Bala J, Noguchi M.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):891-8. doi: 10.1016/j.bbrc.2014.06.077. Epub 2014 Jun 24.

18.

A Functional Role of Fibroblast Growth Factor Receptor 1 (FGFR1) in the Suppression of Influenza A Virus Replication.

Liu X, Lai C, Wang K, Xing L, Yang P, Duan Q, Wang X.

PLoS One. 2015 Apr 24;10(4):e0124651. doi: 10.1371/journal.pone.0124651. eCollection 2015.

19.

Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.

Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M.

J Virol. 2015 Feb;89(4):2220-32. doi: 10.1128/JVI.03385-14. Epub 2014 Dec 3.

20.

A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.

Lee MK, Bottini A, Kim M, Bardaro MF Jr, Zhang Z, Pellecchia M, Choi BS, Varani G.

Chem Commun (Camb). 2014 Jan 11;50(3):368-70. doi: 10.1039/c3cc46973e. Epub 2013 Nov 18. Erratum in: Chem Commun (Camb). 2014 Oct 25;50(83):12578.

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