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Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry.

Brown KS, Keogh MJ, Owsianka AM, Adair R, Patel AH, Arnold JN, Ball JK, Sim RB, Tarr AW, Hickling TP.

Protein Cell. 2010 Jul;1(7):664-74. doi: 10.1007/s13238-010-0088-9. Epub 2010 Jul 29.


Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.

Falson P, Bartosch B, Alsaleh K, Tews BA, Loquet A, Ciczora Y, Riva L, Montigny C, Montpellier C, Duverlie G, PĂ©cheur EI, le Maire M, Cosset FL, Dubuisson J, Penin F.

J Virol. 2015 Oct;89(20):10333-46. doi: 10.1128/JVI.00991-15. Epub 2015 Aug 5.


Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly.

Haddad JG, Rouillé Y, Hanoulle X, Descamps V, Hamze M, Dabboussi F, Baumert TF, Duverlie G, Lavie M, Dubuisson J.

J Virol. 2017 Mar 29;91(8). pii: e00048-17. doi: 10.1128/JVI.00048-17. Print 2017 Apr 15.


Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles.

Russell RS, Kawaguchi K, Meunier JC, Takikawa S, Faulk K, Bukh J, Purcell RH, Emerson SU.

J Viral Hepat. 2009 Sep;16(9):621-32. doi: 10.1111/j.1365-2893.2009.01111.x. Epub 2009 Mar 11.


Identification of new functional regions in hepatitis C virus envelope glycoprotein E2.

Albecka A, Montserret R, Krey T, Tarr AW, Diesis E, Ball JK, Descamps V, Duverlie G, Rey F, Penin F, Dubuisson J.

J Virol. 2011 Feb;85(4):1777-92. doi: 10.1128/JVI.02170-10. Epub 2010 Dec 8.


Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 contain reduced cysteine residues essential for virus entry.

Fraser J, Boo I, Poumbourios P, Drummer HE.

J Biol Chem. 2011 Sep 16;286(37):31984-92. doi: 10.1074/jbc.M111.269605. Epub 2011 Jul 15.


Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

Hamed MR, Brown RJ, Zothner C, Urbanowicz RA, Mason CP, Krarup A, McClure CP, Irving WL, Ball JK, Harris M, Hickling TP, Tarr AW.

J Innate Immun. 2014;6(5):676-84. doi: 10.1159/000362209. Epub 2014 May 15.


Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions.

Helle F, Vieyres G, Elkrief L, Popescu CI, Wychowski C, Descamps V, Castelain S, Roingeard P, Duverlie G, Dubuisson J.

J Virol. 2010 Nov;84(22):11905-15. doi: 10.1128/JVI.01548-10. Epub 2010 Sep 15.


Mannan binding lectin and viral hepatitis.

Brown KS, Ryder SD, Irving WL, Sim RB, Hickling TP.

Immunol Lett. 2007 Jan 15;108(1):34-44. Epub 2006 Nov 20. Review.


The variable regions of hepatitis C virus glycoprotein E2 have an essential structural role in glycoprotein assembly and virion infectivity.

McCaffrey K, Gouklani H, Boo I, Poumbourios P, Drummer HE.

J Gen Virol. 2011 Jan;92(Pt 1):112-21. doi: 10.1099/vir.0.026385-0. Epub 2010 Oct 6.


Analysis of a conserved RGE/RGD motif in HCV E2 in mediating entry.

Rothwangl KB, Rong L.

Virol J. 2009 Jan 26;6:12. doi: 10.1186/1743-422X-6-12.


Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry.

Douam F, Dao Thi VL, Maurin G, Fresquet J, Mompelat D, Zeisel MB, Baumert TF, Cosset FL, Lavillette D.

Hepatology. 2014 Mar;59(3):776-88. doi: 10.1002/hep.26733. Epub 2014 Jan 28.


Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions.

Keck ZY, Op De Beeck A, Hadlock KG, Xia J, Li TK, Dubuisson J, Foung SK.

J Virol. 2004 Sep;78(17):9224-32.


Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: putative CD81 binding region 1 is not involved in CD81 binding.

Rothwangl KB, Manicassamy B, Uprichard SL, Rong L.

Virol J. 2008 Mar 20;5:46. doi: 10.1186/1743-422X-5-46.


Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.

Chen PC, Chuang PK, Chen CH, Chan YT, Chen JR, Lin SW, Ma C, Hsu TL, Wong CH.

ACS Chem Biol. 2014 Jul 18;9(7):1437-43. doi: 10.1021/cb500121c. Epub 2014 May 15.


Hepatitis C virus E1 envelope glycoprotein interacts with apolipoproteins in facilitating entry into hepatocytes.

Mazumdar B, Banerjee A, Meyer K, Ray R.

Hepatology. 2011 Oct;54(4):1149-56. doi: 10.1002/hep.24523. Epub 2011 Jul 25.


Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus.

Lavillette D, Tarr AW, Voisset C, Donot P, Bartosch B, Bain C, Patel AH, Dubuisson J, Ball JK, Cosset FL.

Hepatology. 2005 Feb;41(2):265-74.


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