Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 112

1.

Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

Rosowski EE, Lu D, Julien L, Rodda L, Gaiser RA, Jensen KD, Saeij JP.

J Exp Med. 2011 Jan 17;208(1):195-212. doi: 10.1084/jem.20100717. Epub 2011 Jan 3.

2.

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

Jensen KD, Hu K, Whitmarsh RJ, Hassan MA, Julien L, Lu D, Chen L, Hunter CA, Saeij JP.

Infect Immun. 2013 Jun;81(6):2156-67. doi: 10.1128/IAI.01185-12. Epub 2013 Apr 1.

3.

Transcriptomic analysis reveals Toxoplasma gondii strain-specific differences in host cell response to dense granule protein GRA15.

Liu Q, Gao WW, Elsheikha HM, He JJ, Li FC, Yang WB, Zhu XQ.

Parasitol Res. 2018 Sep;117(9):2785-2793. doi: 10.1007/s00436-018-5966-8. Epub 2018 Jun 19.

PMID:
29916065
4.

Toxoplasma gondii virulence factor ROP18 inhibits the host NF-κB pathway by promoting p65 degradation.

Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J.

J Biol Chem. 2014 May 2;289(18):12578-92. doi: 10.1074/jbc.M113.544718. Epub 2014 Mar 19.

5.

Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.

Gov L, Karimzadeh A, Ueno N, Lodoen MB.

MBio. 2013 Jul 9;4(4). pii: e00255-13. doi: 10.1128/mBio.00255-13.

6.

Toxoplasma GRA15 Activates the NF-κB Pathway through Interactions with TNF Receptor-Associated Factors.

Sangaré LO, Yang N, Konstantinou EK, Lu D, Mukhopadhyay D, Young LH, Saeij JPJ.

MBio. 2019 Jul 16;10(4). pii: e00808-19. doi: 10.1128/mBio.00808-19.

7.

Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains.

Yang N, Farrell A, Niedelman W, Melo M, Lu D, Julien L, Marth GT, Gubbels MJ, Saeij JP.

BMC Genomics. 2013 Jul 10;14:467. doi: 10.1186/1471-2164-14-467.

8.

Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile.

Walzer KA, Wier GM, Dam RA, Srinivasan AR, Borges AL, English ED, Herrmann DC, Schares G, Dubey JP, Boyle JP.

Eukaryot Cell. 2014 Dec;13(12):1507-18. doi: 10.1128/EC.00215-14. Epub 2014 Oct 3.

10.

Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses.

Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB.

Infect Immun. 2014 Oct;82(10):4047-55. doi: 10.1128/IAI.01615-14. Epub 2014 Jul 14.

12.

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

Jensen KD, Wang Y, Wojno ED, Shastri AJ, Hu K, Cornel L, Boedec E, Ong YC, Chien YH, Hunter CA, Boothroyd JC, Saeij JP.

Cell Host Microbe. 2011 Jun 16;9(6):472-83. doi: 10.1016/j.chom.2011.04.015.

13.

Identification of host proteins interacting with Toxoplasma gondii GRA15 (TgGRA15) by yeast two-hybrid system.

Liu Q, Li FC, Elsheikha HM, Sun MM, Zhu XQ.

Parasit Vectors. 2017 Jan 3;10(1):1. doi: 10.1186/s13071-016-1943-1.

14.

Toxoplasma Chinese 1 Strain of WH3Δrop16I/III /gra15II Genetic Background Contributes to Abnormal Pregnant Outcomes in Murine Model.

Wang C, Cheng W, Yu Q, Xing T, Chen S, Liu L, Yu L, Du J, Luo Q, Shen J, Xu Y.

Front Immunol. 2018 Jun 1;9:1222. doi: 10.3389/fimmu.2018.01222. eCollection 2018.

15.

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.

Fox BA, Sanders KL, Rommereim LM, Guevara RB, Bzik DJ.

PLoS Genet. 2016 Jul 22;12(7):e1006189. doi: 10.1371/journal.pgen.1006189. eCollection 2016 Jul.

16.

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

Butcher BA, Fox BA, Rommereim LM, Kim SG, Maurer KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denkers EY.

PLoS Pathog. 2011 Sep;7(9):e1002236. doi: 10.1371/journal.ppat.1002236. Epub 2011 Sep 8.

17.

The GRA15 protein from Toxoplasma gondii enhances host defense responses by activating the interferon stimulator STING.

Wang P, Li S, Zhao Y, Zhang B, Li Y, Liu S, Du H, Cao L, Ou M, Ye X, Li P, Gao X, Wang P, Jing C, Shao F, Yang G, You F.

J Biol Chem. 2019 Aug 15. pii: jbc.RA119.009172. doi: 10.1074/jbc.RA119.009172. [Epub ahead of print]

18.

Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.

Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M.

J Exp Med. 2014 Sep 22;211(10):2013-32. doi: 10.1084/jem.20131272. Epub 2014 Sep 15.

19.

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.

Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, Spooner E, Caradonna K, Burleigh BA, Saeij JP, Ploegh HL, Frickel EM.

PLoS One. 2011;6(9):e24434. doi: 10.1371/journal.pone.0024434. Epub 2011 Sep 8.

20.

Characterization of strain-specific phenotypes associated with knockout of dense granule protein 9 in Toxoplasma gondii.

Guo H, Gao Y, Jia H, Moumouni PFA, Masatani T, Liu M, Lee SH, Galon EM, Li J, Li Y, Tumwebaze MA, Benedicto B, Xuan X.

Mol Biochem Parasitol. 2019 Apr;229:53-61. doi: 10.1016/j.molbiopara.2019.01.003. Epub 2019 Mar 5.

PMID:
30849416

Supplemental Content

Support Center