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Items: 1 to 20 of 154

1.

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

Young JA, Sermwittayawong D, Kim HJ, Nandu S, An N, Erdjument-Bromage H, Tempst P, Coscoy L, Winoto A.

J Biol Chem. 2011 Feb 25;286(8):6521-31. doi: 10.1074/jbc.M110.172288. Epub 2010 Dec 23.

2.

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors.

Castanier C, Zemirli N, Portier A, Garcin D, Bidère N, Vazquez A, Arnoult D.

BMC Biol. 2012 May 24;10:44. doi: 10.1186/1741-7007-10-44.

3.

DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.

Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P.

J Biol Chem. 2013 Aug 23;288(34):24569-80. doi: 10.1074/jbc.M113.479550. Epub 2013 Jul 11.

4.

TRIM21 Promotes Innate Immune Response to RNA Viral Infection through Lys27-Linked Polyubiquitination of MAVS.

Xue B, Li H, Guo M, Wang J, Xu Y, Zou X, Deng R, Li G, Zhu H.

J Virol. 2018 Jun 29;92(14). pii: e00321-18. doi: 10.1128/JVI.00321-18. Print 2018 Jul 15.

PMID:
29743353
5.

Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein.

Ye JS, Kim N, Lee KJ, Nam YR, Lee U, Joo CH.

J Virol. 2014 Nov;88(21):12765-76. doi: 10.1128/JVI.02037-14. Epub 2014 Aug 20.

6.

TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1.

Ning S, Campos AD, Darnay BG, Bentz GL, Pagano JS.

Mol Cell Biol. 2008 Oct;28(20):6536-46. doi: 10.1128/MCB.00785-08. Epub 2008 Aug 18.

7.

Human Metapneumovirus M2-2 Protein Acts as a Negative Regulator of Alpha Interferon Production by Plasmacytoid Dendritic Cells.

Kitagawa Y, Sakai M, Funayama M, Itoh M, Gotoh B.

J Virol. 2017 Sep 27;91(20). pii: e00579-17. doi: 10.1128/JVI.00579-17. Print 2017 Oct 15.

8.

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3.

Higgs R, Ní Gabhann J, Ben Larbi N, Breen EP, Fitzgerald KA, Jefferies CA.

J Immunol. 2008 Aug 1;181(3):1780-6.

9.

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.

tenOever BR, Sharma S, Zou W, Sun Q, Grandvaux N, Julkunen I, Hemmi H, Yamamoto M, Akira S, Yeh WC, Lin R, Hiscott J.

J Virol. 2004 Oct;78(19):10636-49.

10.

Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.

Sjöstrand M, Ambrosi A, Brauner S, Sullivan J, Malin S, Kuchroo VK, Espinosa A, Wahren-Herlenius M.

J Immunol. 2013 Oct 1;191(7):3753-63. doi: 10.4049/jimmunol.1202341. Epub 2013 Aug 23.

11.

Smurf2 negatively modulates RIG-I-dependent antiviral response by targeting VISA/MAVS for ubiquitination and degradation.

Pan Y, Li R, Meng JL, Mao HT, Zhang Y, Zhang J.

J Immunol. 2014 May 15;192(10):4758-64. doi: 10.4049/jimmunol.1302632. Epub 2014 Apr 11.

12.

Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7.

Hu Y, Wang J, Yang B, Zheng N, Qin M, Ji Y, Lin G, Tian L, Wu X, Wu L, Sun B.

J Immunol. 2011 Dec 15;187(12):6456-62. doi: 10.4049/jimmunol.1003691. Epub 2011 Nov 16.

13.

Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of Irf7.

Balachandran S, Venkataraman T, Fisher PB, Barber GN.

J Immunol. 2007 Feb 15;178(4):2429-39.

14.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

15.

Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε.

Pythoud C, Rodrigo WW, Pasqual G, Rothenberger S, Martínez-Sobrido L, de la Torre JC, Kunz S.

J Virol. 2012 Aug;86(15):7728-38. doi: 10.1128/JVI.00187-12. Epub 2012 Apr 24.

16.

MicroRNA-146a induction during influenza H3N2 virus infection targets and regulates TRAF6 levels in human nasal epithelial cells (hNECs).

Deng Y, Yan Y, Tan KS, Liu J, Chow VT, Tao ZZ, Wang DY.

Exp Cell Res. 2017 Mar 15;352(2):184-192. doi: 10.1016/j.yexcr.2017.01.011. Epub 2017 Jan 25.

PMID:
28131813
17.

Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.

Civas A, Génin P, Morin P, Lin R, Hiscott J.

J Biol Chem. 2006 Feb 24;281(8):4856-66. Epub 2005 Dec 27.

18.

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.

Stacey KB, Breen E, Jefferies CA.

PLoS One. 2012;7(3):e34041. doi: 10.1371/journal.pone.0034041. Epub 2012 Mar 30.

19.

Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.

Nousiainen L, Sillanpää M, Jiang M, Thompson J, Taipale J, Julkunen I.

Innate Immun. 2013 Oct;19(5):516-30. doi: 10.1177/1753425912473345. Epub 2013 Feb 12.

PMID:
23405030
20.

Virus Multiplicity of Infection Affects Type I Interferon Subtype Induction Profiles and Interferon-Stimulated Genes.

Zaritsky LA, Bedsaul JR, Zoon KC.

J Virol. 2015 Nov;89(22):11534-48. doi: 10.1128/JVI.01727-15. Epub 2015 Sep 9.

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