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Items: 1 to 20 of 195

1.

Hepatitis C virus core protein abrogates the DDX3 function that enhances IPS-1-mediated IFN-beta induction.

Oshiumi H, Ikeda M, Matsumoto M, Watanabe A, Takeuchi O, Akira S, Kato N, Shimotohno K, Seya T.

PLoS One. 2010 Dec 8;5(12):e14258. doi: 10.1371/journal.pone.0014258.

2.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

3.

Hepatitis C virus core protein interacts with a human DEAD box protein DDX3.

Owsianka AM, Patel AH.

Virology. 1999 May 10;257(2):330-40.

4.

Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations.

Kalkeri G, Lin C, Gopilan J, Sloan K, Rijnbrand R, Kwong AD.

Antimicrob Agents Chemother. 2013 Sep;57(9):4417-26. doi: 10.1128/AAC.00399-13. Epub 2013 Jul 8.

5.

DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication.

Ariumi Y, Kuroki M, Abe K, Dansako H, Ikeda M, Wakita T, Kato N.

J Virol. 2007 Dec;81(24):13922-6. Epub 2007 Sep 12.

6.

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.

Hiscott J, Lacoste J, Lin R.

Biochem Pharmacol. 2006 Nov 30;72(11):1477-84. Epub 2006 Jul 31.

PMID:
16876765
7.

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.

Kaukinen P, Sillanpää M, Kotenko S, Lin R, Hiscott J, Melén K, Julkunen I.

Virol J. 2006 Sep 1;3:66.

8.

Development of mouse hepatocyte lines permissive for hepatitis C virus (HCV).

Aly HH, Oshiumi H, Shime H, Matsumoto M, Wakita T, Shimotohno K, Seya T.

PLoS One. 2011;6(6):e21284. doi: 10.1371/journal.pone.0021284. Epub 2011 Jun 22.

9.

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity.

Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-Kitazume A, Kiyohashi K, Murakawa M, Nishimura-Sakurai Y, Azuma S, Tasaka-Fujita M, Asahina Y, Yoneyama M, Fujita T, Watanabe M.

Hepatology. 2013 Jan;57(1):46-58. doi: 10.1002/hep.26017.

PMID:
22911572
10.

Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH.

J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9.

11.

Functional characterization of domains of IPS-1 using an inducible oligomerization system.

Takamatsu S, Onoguchi K, Onomoto K, Narita R, Takahasi K, Ishidate F, Fujiwara TK, Yoneyama M, Kato H, Fujita T.

PLoS One. 2013;8(1):e53578. doi: 10.1371/journal.pone.0053578. Epub 2013 Jan 7.

12.

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.

Lin R, Lacoste J, Nakhaei P, Sun Q, Yang L, Paz S, Wilkinson P, Julkunen I, Vitour D, Meurs E, Hiscott J.

J Virol. 2006 Jun;80(12):6072-83.

13.

IPS-1 is essential for type III IFN production by hepatocytes and dendritic cells in response to hepatitis C virus infection.

Okamoto M, Oshiumi H, Azuma M, Kato N, Matsumoto M, Seya T.

J Immunol. 2014 Mar 15;192(6):2770-7. doi: 10.4049/jimmunol.1301459. Epub 2014 Feb 14.

14.

Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes.

Ahlén G, Derk E, Weiland M, Jiao J, Rahbin N, Aleman S, Peterson DL, Pokrovskaja K, Grandér D, Frelin L, Sällberg M.

Gut. 2009 Apr;58(4):560-9. doi: 10.1136/gut.2007.147264. Epub 2008 Aug 8.

15.

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein.

Angus AG, Dalrymple D, Boulant S, McGivern DR, Clayton RF, Scott MJ, Adair R, Graham S, Owsianka AM, Targett-Adams P, Li K, Wakita T, McLauchlan J, Lemon SM, Patel AH.

J Gen Virol. 2010 Jan;91(Pt 1):122-32. doi: 10.1099/vir.0.015909-0. Epub 2009 Sep 30.

16.

Hepatitis C virus reveals a novel early control in acute immune response.

Arnaud N, Dabo S, Akazawa D, Fukasawa M, Shinkai-Ouchi F, Hugon J, Wakita T, Meurs EF.

PLoS Pathog. 2011 Oct;7(10):e1002289. doi: 10.1371/journal.ppat.1002289. Epub 2011 Oct 13.

17.

Retinoic acid inducible gene-I (RIG-I) signaling of hepatic stellate cells inhibits hepatitis C virus replication in hepatocytes.

Wang Y, Ye L, Wang X, Li J, Song L, Ho W.

Innate Immun. 2013;19(2):193-202. doi: 10.1177/1753425912460414. Epub 2012 Oct 11.

18.

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.

Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A.

J Biol Chem. 2010 Jun 25;285(26):20252-61. doi: 10.1074/jbc.M109.089912. Epub 2010 Apr 20.

19.

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation.

Schröder M, Baran M, Bowie AG.

EMBO J. 2008 Aug 6;27(15):2147-57. doi: 10.1038/emboj.2008.143. Epub 2008 Jul 17.

20.

DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signalling complexes downstream from MAVS.

Gu L, Fullam A, McCormack N, Höhn Y, Schröder M.

Biochem J. 2017 Feb 15;474(4):571-587. doi: 10.1042/BCJ20160956. Epub 2016 Dec 15.

PMID:
27980081

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