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UNC93B1 mediates host resistance to infection with Toxoplasma gondii.

Melo MB, Kasperkovitz P, Cerny A, Könen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT.

PLoS Pathog. 2010 Aug 26;6(8):e1001071. doi: 10.1371/journal.ppat.1001071.


UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.

Schamber-Reis BL, Petritus PM, Caetano BC, Martinez ER, Okuda K, Golenbock D, Scott P, Gazzinelli RT.

J Biol Chem. 2013 Mar 8;288(10):7127-36. doi: 10.1074/jbc.M112.407684. Epub 2013 Jan 16.


UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii.

Pifer R, Benson A, Sturge CR, Yarovinsky F.

J Biol Chem. 2011 Feb 4;286(5):3307-14. doi: 10.1074/jbc.M110.171025. Epub 2010 Nov 19.


Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii.

Caamaño J, Tato C, Cai G, Villegas EN, Speirs K, Craig L, Alexander J, Hunter CA.

J Immunol. 2000 Nov 15;165(10):5720-8.


Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A.

J Immunol. 2002 Jun 15;168(12):5997-6001.


Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.

Caetano BC, Carmo BB, Melo MB, Cerny A, dos Santos SL, Bartholomeu DC, Golenbock DT, Gazzinelli RT.

J Immunol. 2011 Aug 15;187(4):1903-11. doi: 10.4049/jimmunol.1003911. Epub 2011 Jul 13.


Identification of STAT4-dependent and independent mechanisms of resistance to Toxoplasma gondii.

Cai G, Radzanowski T, Villegas EN, Kastelein R, Hunter CA.

J Immunol. 2000 Sep 1;165(5):2619-27.


Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii.

Neyer LE, Grunig G, Fort M, Remington JS, Rennick D, Hunter CA.

Infect Immun. 1997 May;65(5):1675-82.


Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.

Andrade WA, Souza Mdo C, Ramos-Martinez E, Nagpal K, Dutra MS, Melo MB, Bartholomeu DC, Ghosh S, Golenbock DT, Gazzinelli RT.

Cell Host Microbe. 2013 Jan 16;13(1):42-53. doi: 10.1016/j.chom.2012.12.003. Epub 2013 Jan 3.


Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii.

Koblansky AA, Jankovic D, Oh H, Hieny S, Sungnak W, Mathur R, Hayden MS, Akira S, Sher A, Ghosh S.

Immunity. 2013 Jan 24;38(1):119-30. doi: 10.1016/j.immuni.2012.09.016. Epub 2012 Dec 13.


Interferon-gamma receptor-deficiency renders mice highly susceptible to toxoplasmosis by decreased macrophage activation.

Deckert-Schlüter M, Rang A, Weiner D, Huang S, Wiestler OD, Hof H, Schlüter D.

Lab Invest. 1996 Dec;75(6):827-41.


Functional and quantitative analysis of splenic T cell immune responses following oral toxoplasma gondii infection in mice.

Lee YH, Channon JY, Matsuura T, Schwartzman JD, Shin DW, Kasper LH.

Exp Parasitol. 1999 Mar;91(3):212-21.


Immune responses associated with early survival after peroral infection with Toxoplasma gondii.

McLeod R, Eisenhauer P, Mack D, Brown C, Filice G, Spitalny G.

J Immunol. 1989 May 1;142(9):3247-55.


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