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Items: 1 to 20 of 322

1.

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways.

Melchjorsen J, Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S.

J Virol. 2010 Nov;84(21):11350-8. doi: 10.1128/JVI.01106-10. Epub 2010 Aug 25.

2.

Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1.

Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(2):609-16. Epub 2007 Oct 31.

3.

Regulation of antiviral innate immune responses by RIG-I family of RNA helicases.

Onomoto K, Yoneyama M, Fujita T.

Curr Top Microbiol Immunol. 2007;316:193-205. Review.

PMID:
17969449
4.

H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades.

Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW, Chan MC, Tu W, Guan Y, Lau YL, Peiris JS.

J Infect Dis. 2011 Dec 15;204(12):1866-78. doi: 10.1093/infdis/jir665. Epub 2011 Oct 19.

PMID:
22013225
5.

Enterovirus 2Apro targets MDA5 and MAVS in infected cells.

Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ.

J Virol. 2014 Mar;88(6):3369-78. doi: 10.1128/JVI.02712-13. Epub 2014 Jan 3.

6.

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, Petrilli V, Gomez CE, Perdiguero B, Tschopp J, Pantaleo G, Esteban M, Calandra T.

PLoS Pathog. 2009 Jun;5(6):e1000480. doi: 10.1371/journal.ppat.1000480. Epub 2009 Jun 19.

7.

Herpes simplex virus infection is sensed by both Toll-like receptors and retinoic acid-inducible gene- like receptors, which synergize to induce type I interferon production.

Rasmussen SB, Jensen SB, Nielsen C, Quartin E, Kato H, Chen ZJ, Silverman RH, Akira S, Paludan SR.

J Gen Virol. 2009 Jan;90(Pt 1):74-8. doi: 10.1099/vir.0.005389-0.

8.

MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.

Takaki H, Honda K, Atarashi K, Kobayashi F, Ebihara T, Oshiumi H, Matsumoto M, Shingai M, Seya T.

Mol Immunol. 2014 Feb;57(2):100-10. doi: 10.1016/j.molimm.2013.08.007. Epub 2013 Oct 4.

PMID:
24096085
9.

[Recognition of viral nucleic acids and regulation of type I IFN expression].

Onomoto K, Yoneyama M, Fujita T.

Nihon Rinsho. 2006 Jul;64(7):1236-43. Review. Japanese.

PMID:
16838638
10.

Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.

Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(1):335-45. Epub 2007 Oct 17.

11.
12.

Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS.

Lifland AW, Jung J, Alonas E, Zurla C, Crowe JE Jr, Santangelo PJ.

J Virol. 2012 Aug;86(15):8245-58. doi: 10.1128/JVI.00215-12. Epub 2012 May 23.

13.

Hepatitis A and hepatitis C viruses: divergent infection outcomes marked by similarities in induction and evasion of interferon responses.

Qu L, Lemon SM.

Semin Liver Dis. 2010 Nov;30(4):319-32. doi: 10.1055/s-0030-1267534. Epub 2010 Oct 19. Review.

PMID:
20960373
14.

MDA5 plays a critical role in interferon response during hepatitis C virus infection.

Cao X, Ding Q, Lu J, Tao W, Huang B, Zhao Y, Niu J, Liu YJ, Zhong J.

J Hepatol. 2015 Apr;62(4):771-8. doi: 10.1016/j.jhep.2014.11.007. Epub 2014 Nov 21.

PMID:
25463548
15.

Pyruvate Carboxylase Activates the RIG-I-like Receptor-Mediated Antiviral Immune Response by Targeting the MAVS signalosome.

Cao Z, Zhou Y, Zhu S, Feng J, Chen X, Liu S, Peng N, Yang X, Xu G, Zhu Y.

Sci Rep. 2016 Feb 24;6:22002. doi: 10.1038/srep22002.

16.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

17.

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT.

J Virol. 2015 Jul;89(13):6608-18. doi: 10.1128/JVI.00364-15. Epub 2015 Apr 15.

18.

The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein.

Wei C, Ni C, Song T, Liu Y, Yang X, Zheng Z, Jia Y, Yuan Y, Guan K, Xu Y, Cheng X, Zhang Y, Yang X, Wang Y, Wen C, Wu Q, Shi W, Zhong H.

J Immunol. 2010 Jul 15;185(2):1158-68. doi: 10.4049/jimmunol.0903874. Epub 2010 Jun 16.

19.

The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection.

Errett JS, Suthar MS, McMillan A, Diamond MS, Gale M Jr.

J Virol. 2013 Nov;87(21):11416-25. doi: 10.1128/JVI.01488-13. Epub 2013 Aug 21.

20.

Methylcrotonoyl-CoA carboxylase 1 potentiates RLR-induced NF-κB signaling by targeting MAVS complex.

Cao Z, Xia Z, Zhou Y, Yang X, Hao H, Peng N, Liu S, Zhu Y.

Sci Rep. 2016 Sep 15;6:33557. doi: 10.1038/srep33557.

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