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Items: 1 to 20 of 120

1.

The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.

Liu H, Golebiewski L, Dow EC, Krug RM, Javier RT, Rice AP.

J Virol. 2010 Nov;84(21):11164-74. doi: 10.1128/JVI.01278-10. Epub 2010 Aug 11.

2.

The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions.

Golebiewski L, Liu H, Javier RT, Rice AP.

J Virol. 2011 Oct;85(20):10639-48. doi: 10.1128/JVI.05070-11. Epub 2011 Aug 17.

3.

Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM.

Kumar M, Liu H, Rice AP.

PLoS One. 2012;7(7):e41251. doi: 10.1371/journal.pone.0041251. Epub 2012 Jul 20.

4.

PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.

Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W, Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y.

PLoS One. 2011;6(5):e19511. doi: 10.1371/journal.pone.0019511. Epub 2011 May 23.

5.

Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

Zielecki F, Semmler I, Kalthoff D, Voss D, Mauel S, Gruber AD, Beer M, Wolff T.

J Virol. 2010 Oct;84(20):10708-18. doi: 10.1128/JVI.00610-10. Epub 2010 Aug 4.

6.

Species-specific contribution of the four C-terminal amino acids of influenza A virus NS1 protein to virulence.

Soubies SM, Volmer C, Croville G, Loupias J, Peralta B, Costes P, Lacroux C, Guérin JL, Volmer R.

J Virol. 2010 Jul;84(13):6733-47. doi: 10.1128/JVI.02427-09. Epub 2010 Apr 21.

7.

Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an avian H5N1 influenza A virus.

Fan S, Macken CA, Li C, Ozawa M, Goto H, Iswahyudi NF, Nidom CA, Chen H, Neumann G, Kawaoka Y.

J Virol. 2013 May;87(9):4861-71. doi: 10.1128/JVI.02608-12. Epub 2013 Feb 13.

8.

The PDZ-binding motif of the avian NS1 protein affects transmission of the 2009 influenza A(H1N1) virus.

Kim JI, Hwang MW, Lee I, Park S, Lee S, Bae JY, Heo J, Kim D, Jang SI, Park MS, Kwon HJ, Song JW, Park MS.

Biochem Biophys Res Commun. 2014 Jun 20;449(1):19-25. doi: 10.1016/j.bbrc.2014.04.132. Epub 2014 May 4.

PMID:
24802398
9.

Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens.

Soubies SM, Hoffmann TW, Croville G, Larcher T, Ledevin M, Soubieux D, Quéré P, Guérin JL, Marc D, Volmer R.

J Gen Virol. 2013 Jan;94(Pt 1):50-8. doi: 10.1099/vir.0.045153-0. Epub 2012 Oct 10.

PMID:
23052391
10.

PDZ proteins are expressed and regulated in antigen-presenting cells and are targets of influenza A virus.

Barreda D, Sánchez-Galindo M, López-Flores J, Nava-Castro KE, Bobadilla K, Salgado-Aguayo A, Santos-Mendoza T.

J Leukoc Biol. 2018 Apr;103(4):731-738. doi: 10.1002/JLB.4AB0517-184R. Epub 2017 Dec 27.

PMID:
29345359
11.

Analysis of the PDZ binding specificities of Influenza A virus NS1 proteins.

Thomas M, Kranjec C, Nagasaka K, Matlashewski G, Banks L.

Virol J. 2011 Jan 19;8:25. doi: 10.1186/1743-422X-8-25.

12.

HCV NS4B targets Scribble for proteasome-mediated degradation to facilitate cell transformation.

Hu B, Li S, Zhang Z, Xie S, Hu Y, Huang X, Zheng Y.

Tumour Biol. 2016 Sep;37(9):12387-12396. Epub 2016 Jun 17.

PMID:
27315218
13.

Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells.

Mukherjee S, Majumdar S, Vipat VC, Mishra AC, Chakrabarti AK.

Virol J. 2012 Aug 6;9:149. doi: 10.1186/1743-422X-9-149.

14.

Human T-cell leukemia virus type 1 Tax induces an aberrant clustering of the tumor suppressor Scribble through the PDZ domain-binding motif dependent and independent interaction.

Okajima M, Takahashi M, Higuchi M, Ohsawa T, Yoshida S, Yoshida Y, Oie M, Tanaka Y, Gejyo F, Fujii M.

Virus Genes. 2008 Oct;37(2):231-40. doi: 10.1007/s11262-008-0259-4. Epub 2008 Jul 26.

PMID:
18661220
15.

The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection.

Bavagnoli L, Dundon WG, Garbelli A, Zecchin B, Milani A, Parakkal G, Baldanti F, Paolucci S, Volmer R, Tu Y, Wu C, Capua I, Maga G.

PLoS One. 2011;6(11):e27789. doi: 10.1371/journal.pone.0027789. Epub 2011 Nov 14.

16.

Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens.

Trapp S, Soubieux D, Marty H, Esnault E, Hoffmann TW, Chandenier M, Lion A, Kut E, Quéré P, Larcher T, Ledevin M, Munier S, Naffakh N, Marc D.

J Gen Virol. 2014 Jun;95(Pt 6):1233-43. doi: 10.1099/vir.0.063776-0. Epub 2014 Apr 2.

PMID:
24694396
17.

The distinct binding properties between avian/human influenza A virus NS1 and Postsynaptic density protein-95 (PSD-95), and inhibition of nitric oxide production.

Zhang H, Li W, Wang G, Su Y, Zhang C, Chen X, Xu Y, Li K.

Virol J. 2011 Jun 13;8:298. doi: 10.1186/1743-422X-8-298.

18.

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription.

Kuo RL, Zhao C, Malur M, Krug RM.

Virology. 2010 Dec 20;408(2):146-58. doi: 10.1016/j.virol.2010.09.012. Epub 2010 Oct 8.

19.

A 113-amino-acid truncation at the NS1 C-terminus is a determinant for viral replication of H5N6 avian influenza virus in vitro and in vivo.

Cui X, Ji Y, Wang Z, Du Y, Guo H, Wang L, Chen H, Zhu Q.

Vet Microbiol. 2018 Nov;225:6-16. doi: 10.1016/j.vetmic.2018.09.004. Epub 2018 Sep 13.

PMID:
30322535
20.

The NS1 gene contributes to the virulence of H5N1 avian influenza viruses.

Li Z, Jiang Y, Jiao P, Wang A, Zhao F, Tian G, Wang X, Yu K, Bu Z, Chen H.

J Virol. 2006 Nov;80(22):11115-23. Epub 2006 Sep 13.

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