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Items: 1 to 20 of 159

1.

Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation.

Chang YP, Tsai CC, Huang WC, Wang CY, Chen CL, Lin YS, Kai JI, Hsieh CY, Cheng YL, Choi PC, Chen SH, Chang SP, Liu HS, Lin CF.

J Biol Chem. 2010 Sep 10;285(37):28715-22. doi: 10.1074/jbc.M110.133355. Epub 2010 Jun 30.

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3.

Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2.

Tsai CC, Kai JI, Huang WC, Wang CY, Wang Y, Chen CL, Fang YT, Lin YS, Anderson R, Chen SH, Tsao CW, Lin CF.

J Immunol. 2009 Jul 15;183(2):856-64. doi: 10.4049/jimmunol.0804033. Epub 2009 Jun 19.

4.

Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide.

Li X, Ye Y, Zhou X, Huang C, Wu M.

J Immunol. 2015 Feb 1;194(3):1112-21. doi: 10.4049/jimmunol.1401958. Epub 2014 Dec 22.

5.

Autophagy facilitates cytokine-induced ICAM-1 expression.

Wang CY, Chiang TH, Chen CL, Tseng PC, Chien SY, Chuang YJ, Yang TT, Hsieh CY, Choi PC, Lin CF.

Innate Immun. 2014 Feb;20(2):200-13. doi: 10.1177/1753425913488227. Epub 2013 Jun 10.

PMID:
23751820
6.
7.

Helicobacter pylori infection activates Src homology-2 domain-containing phosphatase 2 to suppress IFN-γ signaling.

Wang YC, Chen CL, Sheu BS, Yang YJ, Tseng PC, Hsieh CY, Lin CF.

J Immunol. 2014 Oct 15;193(8):4149-58. doi: 10.4049/jimmunol.1400594. Epub 2014 Sep 15.

8.

Roles of phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase in the regulation of protein kinase C-alpha activation in interferon-gamma-stimulated macrophages.

Hardy PO, Diallo TO, Matte C, Descoteaux A.

Immunology. 2009 Sep;128(1 Suppl):e652-60. doi: 10.1111/j.1365-2567.2009.03055.x. Epub 2009 Jan 23.

9.

JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1.

Yu L, Min W, He Y, Qin L, Zhang H, Bennett AM, Chen H.

J Biol Chem. 2009 May 15;284(20):13481-8. doi: 10.1074/jbc.M809740200. Epub 2009 Mar 13.

10.

Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma.

Podolsky MA, Solomos AC, Durso LC, Evans SM, Rall GF, Rose RW.

J Neuroimmunol. 2012 Oct 15;251(1-2):33-8. doi: 10.1016/j.jneuroim.2012.06.006. Epub 2012 Jul 4.

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12.

SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells.

Leibowitz MS, Srivastava RM, Andrade Filho PA, Egloff AM, Wang L, Seethala RR, Ferrone S, Ferris RL.

Clin Cancer Res. 2013 Feb 15;19(4):798-808. doi: 10.1158/1078-0432.CCR-12-1517. Epub 2013 Jan 30.

14.

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.

Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M.

J Immunol. 2014 Apr 1;192(7):3328-35. doi: 10.4049/jimmunol.1302822. Epub 2014 Feb 21.

15.

Aqueous extract of Arbutus unedo inhibits STAT1 activation in human breast cancer cell line MDA-MB-231 and human fibroblasts through SHP2 activation.

Mariotto S, Ciampa AR, de Prati AC, Darra E, Vincenzi S, Sega M, Cavalieri E, Shoji K, Suzuki H.

Med Chem. 2008 May;4(3):219-28.

PMID:
18473914
16.

The role of STAT1/IRF-1 on synergistic ROS production and loss of mitochondrial transmembrane potential during hepatic cell death induced by LPS/d-GalN.

Lee HJ, Oh YK, Rhee M, Lim JY, Hwang JY, Park YS, Kwon Y, Choi KH, Jo I, Park SI, Gao B, Kim WH.

J Mol Biol. 2007 Jun 15;369(4):967-84. Epub 2007 Apr 1.

PMID:
17475277
17.

Epigallocatechin-3-gallate sensitizes IFN-γ-stimulated CD4+ T cells to apoptosis via alternative activation of STAT1.

Wu X, Shao F, Yang Y, Gu L, Zheng W, Wu X, Gu Y, Shu Y, Sun Y, Xu Q.

Int Immunopharmacol. 2014 Dec;23(2):434-41. doi: 10.1016/j.intimp.2014.09.014. Epub 2014 Sep 29.

PMID:
25261409
18.

Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1.

Wei J, Lian H, Zhong B, Shu HB.

J Immunol. 2015 Sep 15;195(6):2870-8. doi: 10.4049/jimmunol.1501111. Epub 2015 Jul 31.

19.

Regulation of SHP2 by PTEN/AKT/GSK-3β signaling facilitates IFN-γ resistance in hyperproliferating gastric cancer.

Tseng PC, Huang WC, Chen CL, Sheu BS, Shan YS, Tsai CC, Wang CY, Chen SO, Hsieh CY, Lin CF.

Immunobiology. 2012 Sep;217(9):926-34. doi: 10.1016/j.imbio.2012.01.001. Epub 2012 Jan 4.

PMID:
22325465

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