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Items: 1 to 20 of 143

1.

Sphingosine 1-phosphate-metabolizing enzymes control influenza virus propagation and viral cytopathogenicity.

Seo YJ, Blake C, Alexander S, Hahm B.

J Virol. 2010 Aug;84(16):8124-31. doi: 10.1128/JVI.00510-10. Epub 2010 Jun 2.

2.

Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection.

Vijayan M, Xia C, Song YE, Ngo H, Studstill CJ, Drews K, Fox TE, Johnson MC, Hiscott J, Kester M, Alexander S, Hahm B.

J Immunol. 2017 Jul 15;199(2):677-687. doi: 10.4049/jimmunol.1601959. Epub 2017 Jun 9.

3.

Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm.

Kihara A, Ikeda M, Kariya Y, Lee EY, Lee YM, Igarashi Y.

J Biol Chem. 2003 Apr 18;278(16):14578-85. Epub 2003 Feb 12.

4.

Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus.

Monick MM, Cameron K, Powers LS, Butler NS, McCoy D, Mallampalli RK, Hunninghake GW.

Am J Respir Cell Mol Biol. 2004 Jun;30(6):844-52. Epub 2004 Jan 23.

PMID:
14742298
5.

Sphingosine kinase 1 in viral infections.

Carr JM, Mahalingam S, Bonder CS, Pitson SM.

Rev Med Virol. 2013 Mar;23(2):73-84. doi: 10.1002/rmv.1718. Epub 2012 May 28. Review.

PMID:
22639116
6.

Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence.

Uranbileg B, Ikeda H, Kurano M, Enooku K, Sato M, Saigusa D, Aoki J, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y.

PLoS One. 2016 Feb 17;11(2):e0149462. doi: 10.1371/journal.pone.0149462. eCollection 2016.

7.

First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer.

Brizuela L, Ader I, Mazerolles C, Bocquet M, Malavaud B, Cuvillier O.

Mol Cancer Ther. 2012 Sep;11(9):1841-51. doi: 10.1158/1535-7163.MCT-12-0227. Epub 2012 Jul 10.

8.

Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase.

Ebenezer DL, Fu P, Suryadevara V, Zhao Y, Natarajan V.

Adv Biol Regul. 2017 Jan;63:156-166. doi: 10.1016/j.jbior.2016.09.007. Epub 2016 Sep 29. Review.

9.

Products by the sphingosine kinase/sphingosine 1-phosphate (S1P) lyase pathway but not S1P stimulate mitogenesis.

Kariya Y, Kihara A, Ikeda M, Kikuchi F, Nakamura S, Hashimoto S, Choi CH, Lee YM, Igarashi Y.

Genes Cells. 2005 Jun;10(6):605-15.

10.

Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest.

Gorshkova IA, Wang H, Orbelyan GA, Goya J, Natarajan V, Beiser DG, Vanden Hoek TL, Berdyshev EV.

Life Sci. 2013 Sep 17;93(9-11):359-66. doi: 10.1016/j.lfs.2013.07.017. Epub 2013 Jul 24.

PMID:
23892195
11.

Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors.

Waeber C, Blondeau N, Salomone S.

Drug News Perspect. 2004 Jul-Aug;17(6):365-82. Review.

PMID:
15334188
12.

Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer.

Oskouian B, Sooriyakumaran P, Borowsky AD, Crans A, Dillard-Telm L, Tam YY, Bandhuvula P, Saba JD.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17384-9. Epub 2006 Nov 7.

13.
14.

Assay to measure the secretion of sphingosine-1-phosphate from cells induced by S1P lyase inhibitors.

Loetscher E, Schneider K, Beerli C, Billich A.

Biochem Biophys Res Commun. 2013 Apr 12;433(3):345-8. doi: 10.1016/j.bbrc.2013.03.004. Epub 2013 Mar 14.

PMID:
23499842
15.

Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival.

Maiti A, Takabe K, Hait NC.

Cell Signal. 2017 Apr;32:85-92. doi: 10.1016/j.cellsig.2017.01.021. Epub 2017 Jan 17.

16.

Generation and metabolism of bioactive sphingosine-1-phosphate.

Le Stunff H, Milstien S, Spiegel S.

J Cell Biochem. 2004 Aug 1;92(5):882-99. Review.

PMID:
15258913
17.

New perspectives on the role of sphingosine 1-phosphate in cancer.

Pyne S, Pyne NJ.

Handb Exp Pharmacol. 2013;(216):55-71. doi: 10.1007/978-3-7091-1511-4_3. Review.

PMID:
23563651
18.

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.

Ceccom J, Loukh N, Lauwers-Cances V, Touriol C, Nicaise Y, Gentil C, Uro-Coste E, Pitson S, Maurage CA, Duyckaerts C, Cuvillier O, Delisle MB.

Acta Neuropathol Commun. 2014 Jan 27;2:12. doi: 10.1186/2051-5960-2-12.

19.

Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer.

Uranbileg B, Nishikawa T, Ikeda H, Kurano M, Sato M, Saigusa D, Aoki J, Watanabe T, Yatomi Y.

Clin Colorectal Cancer. 2018 Jun;17(2):e171-e182. doi: 10.1016/j.clcc.2017.11.004. Epub 2017 Nov 21.

PMID:
29223361
20.

Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells.

Liu X, Zhang QH, Yi GH.

Mol Cell Biochem. 2012 Apr;363(1-2):21-33. doi: 10.1007/s11010-011-1154-1. Epub 2011 Nov 24. Review.

PMID:
22113622

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