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Items: 1 to 20 of 85

1.

P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages.

Lees MP, Fuller SJ, McLeod R, Boulter NR, Miller CM, Zakrzewski AM, Mui EJ, Witola WH, Coyne JJ, Hargrave AC, Jamieson SE, Blackwell JM, Wiley JS, Smith NC.

J Immunol. 2010 Jun 15;184(12):7040-6. doi: 10.4049/jimmunol.1000012. Epub 2010 May 19.

2.

Activation of the P2X(7) receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages.

Corrêa G, Marques da Silva C, de Abreu Moreira-Souza AC, Vommaro RC, Coutinho-Silva R.

Microbes Infect. 2010 Jun;12(6):497-504. doi: 10.1016/j.micinf.2010.03.004. Epub 2010 Mar 16.

PMID:
20298798
3.

A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis.

Fernando SL, Saunders BM, Sluyter R, Skarratt KK, Goldberg H, Marks GB, Wiley JS, Britton WJ.

Am J Respir Crit Care Med. 2007 Feb 15;175(4):360-6. Epub 2006 Nov 9.

PMID:
17095747
4.

Inflammatory early events associated to the role of P2X7 receptor in acute murine toxoplasmosis.

Corrêa G, Almeida Lindenberg C, Moreira-Souza AC, Savio LE, Takiya CM, Marques-da-Silva C, Vommaro RC, Coutinho-Silva R.

Immunobiology. 2017 Apr;222(4):676-683. doi: 10.1016/j.imbio.2016.12.007. Epub 2016 Dec 30.

PMID:
28069296
5.

Implication of purinergic P2X7 receptor in M. tuberculosis infection and host interaction mechanisms: a mouse model study.

Santos AA Jr, Rodrigues-Junior V, Zanin RF, Borges TJ, Bonorino C, Coutinho-Silva R, Takyia CM, Santos DS, Campos MM, Morrone FB.

Immunobiology. 2013 Aug;218(8):1104-12. doi: 10.1016/j.imbio.2013.03.003. Epub 2013 Mar 16.

PMID:
23583008
6.

UNC93B1 mediates host resistance to infection with Toxoplasma gondii.

Melo MB, Kasperkovitz P, Cerny A, Könen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT.

PLoS Pathog. 2010 Aug 26;6(8):e1001071. doi: 10.1371/journal.ppat.1001071.

7.

Dysregulation of the inflammatory response to the parasite, Toxoplasma gondii, in P2X7 receptor-deficient mice.

Miller CM, Zakrzewski AM, Ikin RJ, Boulter NR, Katrib M, Lees MP, Fuller SJ, Wiley JS, Smith NC.

Int J Parasitol. 2011 Mar;41(3-4):301-8. doi: 10.1016/j.ijpara.2010.10.001. Epub 2010 Oct 31.

PMID:
21044631
8.

Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor.

Verhoef PA, Kertesy SB, Lundberg K, Kahlenberg JM, Dubyak GR.

J Immunol. 2005 Dec 1;175(11):7623-34.

9.

P2X7 receptor-mediated phosphatidic acid production delays ATP-induced pore opening and cytolysis of RAW 264.7 macrophages.

Le Stunff H, Raymond MN.

Cell Signal. 2007 Sep;19(9):1909-18. Epub 2007 May 5.

PMID:
17540539
10.

A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria.

Saunders BM, Fernando SL, Sluyter R, Britton WJ, Wiley JS.

J Immunol. 2003 Nov 15;171(10):5442-6.

11.

Gene dosage determines the negative effects of polymorphic alleles of the P2X7 receptor on adenosine triphosphate-mediated killing of mycobacteria by human macrophages.

Fernando SL, Saunders BM, Sluyter R, Skarratt KK, Wiley JS, Britton WJ.

J Infect Dis. 2005 Jul 1;192(1):149-55. Epub 2005 May 31.

PMID:
15942904
12.

P2X7 receptor-dependent tuning of gut epithelial responses to infection.

Huang SW, Walker C, Pennock J, Else K, Muller W, Daniels MJ, Pellegrini C, Brough D, Lopez-Castejon G, Cruickshank SM.

Immunol Cell Biol. 2017 Feb;95(2):178-188. doi: 10.1038/icb.2016.75. Epub 2016 Aug 25.

13.

Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis.

Miller CM, Zakrzewski AM, Robinson DP, Fuller SJ, Walker RA, Ikin RJ, Bao SJ, Grigg ME, Wiley JS, Smith NC.

PLoS One. 2015 Jun 8;10(6):e0129048. doi: 10.1371/journal.pone.0129048. eCollection 2015.

14.

A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.

Cavailles P, Flori P, Papapietro O, Bisanz C, Lagrange D, Pilloux L, Massera C, Cristinelli S, Jublot D, Bastien O, Loeuillet C, Aldebert D, Touquet B, Fournié GJ, Cesbron-Delauw MF.

PLoS Pathog. 2014 Apr 3;10(4):e1004005. doi: 10.1371/journal.ppat.1004005. eCollection 2014 Apr.

15.
16.

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.

Song KJ, Ahn HJ, Nam HW.

Korean J Parasitol. 2012 Mar;50(1):1-6. doi: 10.3347/kjp.2012.50.1.1. Epub 2012 Mar 6.

17.

Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γ.

Lang C, Hildebrandt A, Brand F, Opitz L, Dihazi H, Lüder CG.

PLoS Pathog. 2012 Jan;8(1):e1002483. doi: 10.1371/journal.ppat.1002483. Epub 2012 Jan 19.

18.

Phosphatidylserine exposure by Toxoplasma gondii is fundamental to balance the immune response granting survival of the parasite and of the host.

Santos TA, Portes Jde A, Damasceno-Sá JC, Caldas LA, Souza Wd, Damatta RA, Seabra SH.

PLoS One. 2011;6(11):e27867. doi: 10.1371/journal.pone.0027867. Epub 2011 Nov 29.

19.

Specific antibody-dependent killing of Toxoplasma gondii by normal macrophages.

Anderson SE Jr, Bautista SC, Remington JS.

Clin Exp Immunol. 1976 Dec;26(3):375-80.

20.

A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages.

Shemon AN, Sluyter R, Fernando SL, Clarke AL, Dao-Ung LP, Skarratt KK, Saunders BM, Tan KS, Gu BJ, Fuller SJ, Britton WJ, Petrou S, Wiley JS.

J Biol Chem. 2006 Jan 27;281(4):2079-86. Epub 2005 Nov 1.

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