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Items: 1 to 20 of 144

1.
2.

Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication.

Tani J, Shimamoto S, Mori K, Kato N, Moriishi K, Matsuura Y, Tokumitsu H, Tsuchiya M, Fujimoto T, Kato K, Miyoshi H, Masaki T, Kobayashi R.

Liver Int. 2013 Aug;33(7):1008-18. doi: 10.1111/liv.12151. Epub 2013 Mar 24.

PMID:
23522085
3.

Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase.

He Y, Nakao H, Tan SL, Polyak SJ, Neddermann P, Vijaysri S, Jacobs BL, Katze MG.

J Virol. 2002 Sep;76(18):9207-17.

4.

Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.

Wang J, Tong W, Zhang X, Chen L, Yi Z, Pan T, Hu Y, Xiang L, Yuan Z.

FEBS Lett. 2006 Aug 7;580(18):4392-400. Epub 2006 Jul 17.

5.

Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis.

Jiang X, Kanda T, Wu S, Nakamoto S, Wakita T, Shirasawa H, Yokosuka O.

PLoS One. 2014 Nov 19;9(11):e113499. doi: 10.1371/journal.pone.0113499. eCollection 2014.

7.

Kushenin induces the apoptosis of HCV-infected cells by blocking the PI3K-Akt-mTOR pathway via inhibiting NS5A.

Zhou Y, Chen N, Liu X, Lin S, Luo W, Liu M.

Exp Cell Res. 2016 Jul 1;345(1):108-14. doi: 10.1016/j.yexcr.2016.05.002. Epub 2016 May 26.

PMID:
27237092
8.

Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.

George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH.

J Biol Chem. 2012 Feb 10;287(7):5042-58. doi: 10.1074/jbc.M111.308916. Epub 2011 Dec 19.

9.

Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis.

Park CY, Choi SH, Kang SM, Kang JI, Ahn BY, Kim H, Jung G, Choi KY, Hwang SB.

J Hepatol. 2009 Nov;51(5):853-64. doi: 10.1016/j.jhep.2009.06.026. Epub 2009 Aug 12.

PMID:
19726098
10.

Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity.

Muraoka T, Ichikawa T, Taura N, Miyaaki H, Takeshita S, Akiyama M, Miuma S, Ozawa E, Isomoto H, Takeshima F, Nakao K.

Mol Med Rep. 2012 Feb;5(2):331-5. doi: 10.3892/mmr.2011.662. Epub 2011 Nov 3.

PMID:
22052332
11.

Suppressor of cytokine signaling 3 suppresses hepatitis C virus replication in an mTOR-dependent manner.

Shao RX, Zhang L, Peng LF, Sun E, Chung WJ, Jang JY, Tsai WL, Hyppolite G, Chung RT.

J Virol. 2010 Jun;84(12):6060-9. doi: 10.1128/JVI.02484-09. Epub 2010 Apr 7.

12.

A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication.

Okamoto T, Omori H, Kaname Y, Abe T, Nishimura Y, Suzuki T, Miyamura T, Yoshimori T, Moriishi K, Matsuura Y.

J Virol. 2008 Apr;82(7):3480-9. doi: 10.1128/JVI.02253-07. Epub 2008 Jan 23.

13.

The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade.

Street A, Macdonald A, Crowder K, Harris M.

J Biol Chem. 2004 Mar 26;279(13):12232-41. Epub 2004 Jan 5.

14.

Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions.

Goonawardane N, Gebhardt A, Bartlett C, Pichlmair A, Harris M.

J Virol. 2017 Aug 10;91(17). pii: e00805-17. doi: 10.1128/JVI.00805-17. Print 2017 Sep 1.

16.

Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway.

Guo H, Zhou T, Jiang D, Cuconati A, Xiao GH, Block TM, Guo JT.

J Virol. 2007 Sep;81(18):10072-80. Epub 2007 Jul 3.

17.

Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases.

Lee KY, Chen YH, Hsu SC, Yu MJ.

PLoS One. 2016 Nov 22;11(11):e0166763. doi: 10.1371/journal.pone.0166763. eCollection 2016.

18.

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

Huang Y, Staschke K, De Francesco R, Tan SL.

Virology. 2007 Jul 20;364(1):1-9. Epub 2007 Apr 2. Review.

19.

Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.

Parvaiz F, Manzoor S, Iqbal J, Sarkar-Dutta M, Imran M, Waris G.

World J Gastroenterol. 2015 Nov 21;21(43):12361-9. doi: 10.3748/wjg.v21.i43.12361.

20.

Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagation.

Lim YS, Hwang SB.

J Biol Chem. 2011 Apr 1;286(13):11290-8. doi: 10.1074/jbc.M110.194472. Epub 2011 Feb 5.

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